Results 1 to 10 of about 141,530 (342)

The renin angiotensin aldosterone system. [PDF]

Pflugers Arch
AbstractIn this review, we will cover (i) the proteolytic cascade of the RAAS, (ii) its regulation by multiple feedback-controlled parameters, and (iii) the major effects of the RAAS. For the effects of the RAAS, we focus on the role of the RAAS in the regulation of volume homeostasis and vascular tone, as major determinants of arterial blood pressure.
Triebel H, Castrop H.
europepmc   +6 more sources

Hypertension: Renin-Angiotensin-Aldosterone System Alterations [PDF]

Circulation Research, 2015
Blockers of the renin-angiotensin-aldosterone system (RAAS), that is, renin inhibitors, angiotensin (Ang)-converting enzyme (ACE) inhibitors, Ang II type 1 receptor antagonists, and mineralocorticoid receptor antagonists, are a cornerstone in the ...
Danser, A.H.J. (Jan), Esch, J.H.M. (Joep) van, Meiracker, A.H. (Anton) van den, Riet, L. (Luuk) te, Roks, A.J.M. (Anton)   +4 more
core   +4 more sources

Quarterly injectable hormonal contraceptive does not increase the activity of the renin-angiotensin-aldosterone system in women without cardiovascular risk factors [PDF]

Revista Brasileira de Ginecologia e Obstetrícia
Objective: To test the hypothesis that the quarterly injectable contraceptive increases the activity of the renin-angiotensin-aldosterone system. Methods: This was a cross-sectional observational study that included eutrophic, irregularly active women ...
Alice Miranda de Oliveira, Priscilla Araújo dos Santos, Pedro Elias Santos Souza, Marvyn de Santana do Sacramento, Clóvis Figueiredo Souza Filho, Ana Marice Texeira Ladeia, Jefferson Petto   +6 more
doaj   +2 more sources

Updates on the Renin–Angiotensin–Aldosterone System and the Cardiovascular Continuum [PDF]

Biomedicines
The cardiovascular continuum describes how several cardiovascular risk factors contribute to the development of atherothrombosis, ischemic heart disease, and peripheral arteriopathy, leading to cardiac and renal failure and ultimately death.
Dana Pop, Alexandra Dădârlat-Pop, Raluca Tomoaia, Dumitru Zdrenghea, Bogdan Caloian   +4 more
doaj   +2 more sources

Genetic pathogenesis of essential arterial hypertension (the review) [PDF]

Саратовский научно-медицинский журнал, 2011
It is proved that genetic factors may be considered as fundamental in the development of essential arterial hypertension (AH). Important role in this process belongs to the genes whose products are involved in regulating blood pressure - adrenergic ...
Ruta A.V., Borodulin V.B., Svistunov А.А., Shevchenko O.V., Bychkov E.N.   +4 more
doaj   +3 more sources

Correlation of serum chloride concentrations with components of the renin‐angiotensin‐aldosterone system in a dog with congestive heart failure [PDF]

Journal of Veterinary Internal Medicine
A 7‐year‐old male castrated Cavalier King Charles Spaniel was hospitalized for 12 days for treatment of severe congestive heart failure secondary to myxomatous mitral valve disease.
Cailey Banken, Autumn N. Harris, Rachel Conway, Eduardo J. Benjamin, Robin Shoemaker, Darcy Adin   +5 more
doaj   +2 more sources

Early use of renin-angiotensin-aldosterone system inhibitors and stable renal function in familial focal segmental glomerulosclerosis with ACTN4 mutation: a case report and literature review. [PDF]

BMC Nephrol
Miyasako K, Maeoka Y, Adachi Y, Tamura R, Ishiuchi N, Nagano C, Nozu K, Masaki T.   +7 more
europepmc   +3 more sources

A perspective on small molecules targeting the renin-angiotensin-aldosterone system and their utility in cardiovascular diseases: exploring the structural insights for rational drug discovery and development. [PDF]

RSC Med Chem
Bansal N, Kathuria D, Babu AM, Dhiman S, Lakhanpal S, Prasad KN, Kumar R, Tyagi Y, Kumar B, Singh MP, Gaidhane AM.   +10 more
europepmc   +3 more sources

Assessment of the effects of antihypertensive drugs in patients suffering from hypertension in Kurdistan

Advanced Medical Journal, 2023
Background and objectives: Hypertension is an important cardiovascular disease that carries a high rate of mortality and morbidity if not controlled. Significant complications of untreated hypertension include vascular atherosclerosis, chronic kidney ...
Mohammed Hasan Almeshhadani, Khasro Adel Faeq, Kamal Mohammed Nidhamy, Abdulsatar Kamil Faeq   +3 more
doaj   +1 more source

Clinical Determinants and Prognostic Implications of Renin and Aldosterone in Patients with Symptomatic Heart Failure [PDF]

, 2020
Aims Activation of the renin-angiotensin-aldosterone system plays an important role in the pathophysiology of heart failure (HF) and has been associated with poor prognosis.
Anker, Stefan D., Dickstein, Kenneth, Duarte, Kevin, Ferreira, Joao Pedro, Girerd, Nicolas, Kobayashi, Masatake, Lamiral, Zohra, Lang, Chim C., Metra, Macro, Ng, Leong L., Preud'homme, Gregoire, Rossignol, Patrick, Samani, Nilesh J., Stienen, Susan, ter Maaten, Jozine M., van Veldhuisen, Dirk J., Voors, Adriaan A., Zannad, Faiez   +17 more
core   +5 more sources