Results 111 to 120 of about 52,295 (246)

Beyond the circulating renin angiotensin aldosterone system

Frontiers in Endocrinology, 2014
Walmor eDe Mello
doaj   +1 more source

Aldosterone, aldosterone receptor blockers and chronic kidney disease

Zdravniški Vestnik, 2011
Chronic kidney disease (CKD) is a worldwide public health problem and an important risk factor for cardiovascular events, morbidity and mortality. The renin-angiotensin-aldosteron system (RAAS) drugs, angiotensin-converting enzyme inhibitors and/or ...
Sebastjan Bevc
doaj  

Transcriptome Analysis Reveals Distinct Molecular Signatures Between Erosive and Non‐Erosive Oral Lichen Planus

Oral Diseases, EarlyView.
ABSTRACT Objectives To identify molecular mechanisms distinguishing the erosive subtype of oral lichen planus (EOLP) from the non‐erosive subtype (NEOLP) through transcriptomic analysis. Methods We analysed bulk RNA‐seq data from 30 buccal mucosa samples (13 EOLP, 17 NEOLP) using differential expression, Gene Set Enrichment Analysis (GSEA ...
Kisung Sheen, Chaerim Song, Kanghyun Kwon, Seoyeon Kim, Hye‐Ji Park, Man S. Kim   +5 more
wiley   +1 more source

Influence of menstrual cycle phase on inflammatory and vascular responses to acute passive heating in healthy young women

Experimental Physiology, EarlyView.
Abstract The aim of this study was to determine whether inflammatory and vascular responses to passive heating differ between the early follicular phase (EFP) and the mid‐luteal phase (MLP) of the menstrual cycle. Ten healthy, naturally menstruating females (26 ± 3 years of age; body mass index 21.4 ± 1.9 kg/m2) were assessed during EFP and MLP ...
Yunuo Su, Emma O'Donnell, Stephen J. Bailey, Christof A. Leicht   +3 more
wiley   +1 more source

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

Experimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu, Xingyu Qiu, Nan Xu, Gensheng Zhang, Enyin Lai, Liang Zhao   +5 more
wiley   +1 more source

Contributions of vascular ageing to late‐onset Alzheimer's disease

Experimental Physiology, EarlyView.
Abstract Late‐onset Alzheimer's disease (LOAD) is an age‐related disease that is strongly associated with vascular risk factors and cerebrovascular impairments. As such, changes in the vasculature with advancing age likely contribute to LOAD, but the mechanisms underlying these contributions remain incompletely understood.
Skylyn J. Ferguson, Young Deanna Choi, Ashley E. Walker   +2 more
wiley   +1 more source

Toward endotype-guided renin-angiotensin-aldosterone system modulation in septic shock. [PDF]

Crit Care
Khanna AK, Annoni F, Picod A.
europepmc   +1 more source

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

Experimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou, Paschalis Karakasis, Panagiotis Theofilis, Konstantinos Pamporis, Panayotis K. Vlachakis, Anastasios Apostolos, Nikolaos Ktenopoulos, Barbara Fyntanidou, Efstratios Karagiannidis, Dimitrios Patoulias, Antonios P Antoniadis, Nikolaos Fragakis   +11 more
wiley   +1 more source

Effects of reducing sedentary behaviour on heart rate variability and cardio‐metabolic biomarkers in desk workers with untreated high blood pressure

Experimental Physiology, EarlyView.
Abstract Lower sedentary behaviour (SB) has been associated with reduced cardiovascular disease and mortality. Yet, few trials have evaluated cardiovascular mechanisms of benefit. We examined the effects of a SB reduction intervention on heart rate variability (HRV) and cardio‐metabolic biomarkers.
Abdullah Bandar Alansare, Matthew F. Muldoon, Subashan Perera, Kimberly A. Huber, Molly B. Conroy, John M. Jakicic, Bethany Barone Gibbs   +6 more
wiley   +1 more source

Renin-Angiotensin-Aldosterone System in Preeclampsia: Pathophysiological Insights and Links to Vascular Dementia. [PDF]

Arterioscler Thromb Vasc Biol
Lutshumba J, Mirsky E, Bullens KA, Smith EG, Ndashaala EL, Finch R.   +5 more
europepmc   +1 more source