Results 141 to 150 of about 141,530 (342)
Effect of Melatonin on the Renin-Angiotensin-Aldosterone System in l-NAME-Induced Hypertension
Molecules, 2018 The renin-angiotensin-aldosterone system (RAAS) is a dominant player in several cardiovascular pathologies. This study investigated whether alterations induced by l-NAME, (NLG)-nitro-l-arginine methyl ester, a nitric oxide synthase inhibitor, and the ...
F. Simko +9 more
semanticscholar +1 more source
Diabetes, Obesity and Metabolism, EarlyView.Abstract Introduction Diabetic kidney disease (DKD) and diabetic nephropathy (DN) affect around 40% of diabetic patients but lack accurate risk prediction tools that include social determinants and demographic complexity. We developed and validated an ensemble machine learning model for three‐year DKD/DN risk prediction with deployment readiness ...
Ayla M. Tourkmani +5 more
wiley +1 more source
Pharmaceuticals, 2010 Patients with hypertension often manifest a dysregulated renin-angiotensin-aldosterone system (RAAS). Most of the available treatment approaches for hypertension are targeted towards the RAAS including direct renin inhibition, ACE inhibition, angiotensin
Peter P. Sayeski, Annet Kirabo
doaj +1 more source
FP624INTERACTION BETWEEN PARATHYROID HORMONE AND RENIN ANGIOTENSIN ALDOSTERONE SYSTEM IN HEMODIALYSIS PATIENTS [PDF]
, 2018 Keiji Kono +5 more
openalex +1 more source
Renin-angiotensin-aldosterone system activation in long-standing type 1 diabetes.
JCI Insight, 2018 BACKGROUND In type 1 diabetes (T1D), adjuvant treatment with inhibitors of the renin-angiotensin-aldosterone system (RAAS), which dilate the efferent arteriole, is associated with prevention of progressive albuminuria and renal dysfunction.
J. Lovshin +17 more
semanticscholar +1 more source
Diabetes, Obesity and Metabolism, EarlyView.Abstract Background Older adults with type 2 diabetes (T2DM) are less likely to receive sodium–glucose cotransporter‐2 (SGLT2) inhibitors, despite their proven cardio‐renal benefits and safety. Whether this age‐related gap is driven by frailty, sex, or other factors remains unclear.
Changyuan Yang +6 more
wiley +1 more source
Diabetic kidney disease, biomarkers, and finerenone
Diabetes, Obesity and Metabolism, EarlyView.Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley +1 more source
RESPONSE OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM TO FUROSEMIDE AND ACUTE SALT LOADING IN THE FETAL LAMB [PDF]
, 1977 Sharon R Siegel +2 more
openalex +1 more source
Diabetes, Obesity and Metabolism, EarlyView.Abstract Aims We investigated whether dipeptidyl peptidase‐4 inhibitor (DPP‐4i) use was associated with a higher risk of acute pancreatitis compared with sodium–glucose cotransporter 2 inhibitor (SGLT2i) use in antidiabetic medication‐naïve individuals.
Takashi Tatewaki +3 more
wiley +1 more source
International Journal of Nephrology and Renovascular Disease, 2012 Yoshiyuki Morishita1, Minami Watanabe1, Shiho Hanawa1, Osamu Iimura2, Sadao Tsunematsu3, Kenichi Ishibashi4, Eiji Kusano11Division of Nephrology, Department of Medicine, Jichi Medical University, Tochigi, Japan; 2Kumakura Clinic, Tochigi, Japan; 3Yuki ...
Morishita Y +6 more
doaj