Results 161 to 170 of about 52,295 (246)

Apiotrichum‐Centered Fungal Interaction Network Disturbance Correlates With Increased Arterial Stiffness

Aging Cell, Volume 25, Issue 8, August 2026.
Apiotrichum‐centered gut fungal network disturbance correlates with increased arterial stiffness. Five driver genera including Apiotrichum, Mycothermus, Flavocillium, Hyaloscypha, and Microscypha regulate the interaction shift. Thirty‐nine metabolites comprising organic acids, fatty acyls, and sucrose target vasoconstriction regulators CYP11B2, ROCK2 ...
Jiarui Chen, Jialin He, Bingqi Ye, Jialu Yang, Ludi Liu, Jingmeng Ju, Sinan Li, Benjie Li, Min Xia, Yan Liu   +9 more
wiley   +1 more source

Mitoquinone Prevents Cardiac Dysfunction by Normalizing Mitochondrial ROS and Calcium Handling in Acute Myocardial Infarction

Acta Physiologica, Volume 242, Issue 8, August 2026.
ABSTRACT Acute myocardial infarction (MI) is the leading cause of heart failure (HF). However, the role of mitochondrial ROS (ROSm) in early MI dysfunction remains unclear. This study aimed to evaluate the impact of MitoQ on cardiac function in cases of heart HF following MI.
Carolina Falcão Ximenes, Pietra Zava Lorencini, Carmen Castardeli, Marlon Ramos Rosado Machado, Katyana Kaline Silva Ferreira, Sara Bianca Oliveira Mendes, Anna Karolina Nascimento Costa, Mario Morais Silva, Sérgio Ricardo Aluotto Scalzo, Marcos Eliezeck, Silvia Guatimosim, Eduardo Hertel Ribeiro, Donald M. Bers, Aurélia Araujo Fernandes, Ivanita Stefanon   +14 more
wiley   +1 more source

Hypertension in obstructive sleep apnea: the hidden role of renin-angiotensin-aldosterone system dysregulation. [PDF]

Trop Med Health
Loh HH, Tay SP, Koa AJ, Yong MC, Said A, Chai CS, Malik NMA, Su AT, Tang BBC, Tan FHS, Azizan EA, Sukor N.   +11 more
europepmc   +1 more source

Apparent Bilateral Aldosterone Suppression During Adrenal Vein Sampling: An Artefact of the Liaison Chemiluminescence Immunoassay and Other Causes Revealed by Comparisons With Another Commercial Immunoassay and Mass Spectrometry

Clinical Endocrinology, Volume 105, Issue 2, Page 175-184, August 2026.
ABSTRACT Objective Subtyping of primary aldosteronism usually requires adrenal vein sampling (AVS). Interpretation can be compromised by apparent bilateral aldosterone suppression (ABAS), which we hypothesised reflects an artefact of the Liaison immunoassay of aldosterone.
Christina Pamporaki, Carmina T. Fuss, Ralph Kickuth, Lydia Kürzinger, Mirko Peitzsch, Sybille Fuld, Manuel Schulze, Jun Yang, Martin Reincke, Sven Gruber, Felix Beuschlein, Jacques W. M. Lenders, Graeme Eisenhofer   +12 more
wiley   +1 more source

Alpha-7 nicotinic acetylcholine receptor: targeting the interplay between inflammation, renin-angiotensin aldosterone system, and nervous system for the novel treatment of heart failure. [PDF]

Front Pharmacol
Swiderski J, Gadanec LK, Hearth S, Rowlands BD, Murphy AJ, Apostolopoulos V, Zulli A.   +6 more
europepmc   +1 more source

Exploring Risks of Adverse Drug Events From Single Drug to Three‐Drug Combination

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Use of three‐drug combinations is common and could increase the risk of adverse drug events (ADEs). Signals of ADEs from three‐drug combinations could be identified from real‐world data, and the risks of ADEs from single drug exposure to three‐drug combination exposure could be illustrated by a graphic model.
Yi Shi, Anna Sun, Chien‐Wei Chiang, Yuedi Yang, Katherine M. Hunold, Jing Xu, Mu Shan, Allison Lu, Massimiliano Russo, Jeffrey M. Caterino, Michael T. Eadon, Lang Li, Jing Su, Macarius Donneyong, Pengyue Zhang   +14 more
wiley   +1 more source

Renin-angiotensin aldosterone system inhibitors usage among hospitalized patients with acute kidney injury: a retrospective study. [PDF]

Ann Med
Xu L, Zhou Q, Tang L, Xu D, Yang L, Zheng X.   +5 more
europepmc   +1 more source

Underdiagnosed and Undertreated: Obesity and Its Cardiometabolic Burden in Swedish Clinical Practice—Insights From the AROS Database

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6787-6800, August 2026.
ABSTRACT Aims To quantify real‐world diagnosis and treatment of obesity in Sweden, describe cardiometabolic comorbidity burden across obesity classes, and compare long‐term cardiovascular outcomes with the general population. Materials and Methods This population‐based cohort study used the AROS (Analysis of Real‐world data of patients with Obesity in ...
Viveca Ritsinger, Magnus Sundbom, Jonatan Dereke, Åsa Ericsson, Thomas Cars, Maria K. Svensson, Anna Norhammar   +6 more
wiley   +1 more source

Prediabetes, Malignant Ventricular Hypertrophy and Stroke: The SPRINT Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6725-6734, August 2026.
ABSTRACT Aims Prediabetes and left ventricular hypertrophy (LVH) are common risk factors in adults with hypertension. Whether their coexistence, particularly in the presence of subclinical myocardial injury or stress (malignant LVH), confers a heightened stroke risk is unknown.
Arnaud D. Kaze, Stephen P. Juraschek, Jordana B. Cohen, Siddharth Singh, Chiadi E. Ndumele, Christie M. Ballantyne, Jarrett D. Berry, Justin B. Echouffo‐Tcheugui   +7 more
wiley   +1 more source