Results 161 to 170 of about 17,321,273 (254)

The Renin-Angiotensin-Aldosterone System (RAAS): Beyond Cardiovascular Regulation. [PDF]

Vet Sci
Valentini A, Heilmann RM, Kühne A, Biagini L, De Bellis D, Rossi G.   +5 more
europepmc   +1 more source

Maternal protein restriction programs the ageing kidney: Proteomic signatures of early‐life origin renal and metabolic dysfunction

The Journal of Physiology, EarlyView.
Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires, Matheus Naia Fioretto, Marcel Rodrigues Ferreira, Isabelle Tenori Ribeiro, Luísa Annibal Barata, Flávia Alessandra Maciel, Lucas Sobrinho Lemos, Renato Mattos, Luiz Marcos Frediane Portela, Patrick Vieira de Souza, Luisa Correia Gomes, Gustavo Monezzi Cordeiro, Wellerson Rodrigo Scarano, Patrícia Aline Boer, Jose Antonio Rocha Gontijo, Luis Antonio Justulin   +15 more
wiley   +1 more source

Beyond the Heart‐Lung Axis: A Review of the Crosstalk Between the Hemodynamic, Neurohormonal, and Immune Systems in Pulmonary Hypertension

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Pulmonary hypertension is driven by dynamic crosstalk beyond the physical connection between the heart and lung, involving neurohormonal systems, immune pathways, and peripheral organs. This review highlights how multisystem signaling contributes to disease progression and may reveal new diagnostic and therapeutic targets.
Alejandro A. Vega, Juliet M. Alfaro, David S. Pinto, Maryam Emamimeybodi, Soban Umar   +4 more
wiley   +1 more source

The Renin-Angiotensin-Aldosterone System in Cardiac Surgery and Angiotensin II Therapy for Vasoplegia. [PDF]

Anesth Analg
Zarbock A, Vincent JL, De Backer D, Bellomo R, Legrand M, Khanna AK, Ostermann M, Kotfis K, Filippo A, Wieruszewski PM, Leone M, Girardis M, Ferrer R, Kotani Y, Pickkers P, De Pascale G, Tissieres P, Landoni G.   +17 more
europepmc   +1 more source

Axial Connectivity of the Lung Microbiome: A Review of Interorgan Crosstalk

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
The human microbiome mediates immune homeostasis and metabolic signaling across organs. Beyond the gut‐lung axis, crosstalk between the lung and other organ systems is less recognized. This review assesses the axial connectivity of the lung microbiome across the gut, brain, skin, heart, kidney, and liver.
Mathangi Palanivel, Jayanth Kumar Narayana, Sanjay H. Chotirmall   +2 more
wiley   +1 more source

Causal Effects of Renin-Angiotensin-Aldosterone System Inhibition on Renal Function in Patients With Chronic Kidney Disease: A Quasi-Experimental Study. [PDF]

Clin Transl Sci
Oh TR, Park J, Choi HS, Rhee H, Kang G.
europepmc   +1 more source

SGLT2i in heart failure: Cardiorenal mechanisms, clinical evidence and translational perspectives

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
SGLT2 inhibitors improve heart failure outcomes through integrated cardiorenal mechanisms. In the kidney, they reduce glucose and sodium reabsorption, promoting natriuresis, osmotic diuresis and renal protection. In the heart, they enhance myocardial energetics, reduce inflammation, oxidative stress, fibrosis and adverse remodelling, resulting in fewer
Jelica Grujic‐Milanovic, Jovana Rajkovic, Radmila Novakovic, Javad Sharifi‐Rad, Daniela Calina   +4 more
wiley   +1 more source

Vasopressin and fluid retention after liver resection: Comparison with the renin-angiotensin-aldosterone system by surgical extent and liver function. [PDF]

World J Gastroenterol
Aoki Y, Kawano Y, Ga R, Endo K, Ueda J, Shimizu T, Yoshida H.   +6 more
europepmc   +1 more source

Radiotherapy‐Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments

MedComm, Volume 7, Issue 10, October 2026.
Radiotherapy for malignancies frequently injures the organs’ systems through oxidative stress, fibrosis, inflammation, and vascular damage. This review systematically maps the epidemiology, pathogenesis, and emerging therapies to propose a mechanism‑network‑targeted framework for integrated, personalized care in radiation oncology.
Xiaowen Ma, Xiaoxuan Zhang, Pujun Zhao, Jiaxin Yang, Zhihao Li, Xiaoyang Han, Yixuan Wang, Zhenzhen Cui, Nian Liu, Min Li   +9 more
wiley   +1 more source

Renin-angiotensin-aldosterone system inhibition exacerbates anemia in sickle cell disease.

Blood
Eskandari N, Pappano E, Ruiz MA, Mahmud N, Ren G, Ivy Z, Gaitonde S, Gordeuk VR, Gladwin MT, Malik P, Quinn CT, Saraf SL.   +11 more
europepmc   +1 more source