Results 171 to 180 of about 80,731 (303)

Renin-angiotensin-aldosterone system in the elderly: rational use of aliskiren in managing hypertension

, 2009
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldThe overall purpose of hypertension treatment is 2-fold.
Andersen, Karl, Karl Andersen
core  

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1685-1695, June 2026.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

The Renin-Angiotensin-Aldosterone System (RAAS): Beyond Cardiovascular Regulation. [PDF]

Vet Sci
Valentini A, Heilmann RM, Kühne A, Biagini L, De Bellis D, Rossi G.   +5 more
europepmc   +1 more source

New‐Onset Acute Heart Failure With Reduced Ejection Fraction Associated With Severe Microcytic Anemia

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Graphical abstract summarizing a case of new‐onset HFrEF associated with profound microcytic anemia, highlighting severe anemia as a potential reversible trigger of acute cardiac decompensation. ABSTRACT Severe microcytic anemia may serve as a potentially reversible precipitating factor in heart failure with reduced ejection fraction (HFrEF). This case
Annabel Ricci, Cassandra Hunt, Chabelly Gomez, Gerson Santafe, Aimee Gonzalez, Martha Duarte   +5 more
wiley   +1 more source

Causal Effects of Renin-Angiotensin-Aldosterone System Inhibition on Renal Function in Patients With Chronic Kidney Disease: A Quasi-Experimental Study. [PDF]

Clin Transl Sci
Oh TR, Park J, Choi HS, Rhee H, Kang G.
europepmc   +1 more source

Beta Blocker Toxicity at Therapeutic Doses: A Look Into Carvedilol Use in the Elderly

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Beta‐blocker toxicity does not occur only in overdose situations. In vulnerable populations such as children and the elderly, therapeutic doses may produce cumulative toxic effects similar to those seen in acute overdose. These patients require monitoring that extends beyond basic laboratory investigations to preempt cumulative toxicity.
Samuel Amo‐Tachie
wiley   +1 more source

The Renin-Angiotensin-Aldosterone System in Cardiac Surgery and Angiotensin II Therapy for Vasoplegia. [PDF]

Anesth Analg
Zarbock A, Vincent JL, De Backer D, Bellomo R, Legrand M, Khanna AK, Ostermann M, Kotfis K, Filippo A, Wieruszewski PM, Leone M, Girardis M, Ferrer R, Kotani Y, Pickkers P, De Pascale G, Tissieres P, Landoni G.   +17 more
europepmc   +1 more source

Reverse Diagnostic Thinking for Aortic Coarctation Using the Renal Artery Bilateral Parvus et Tardus as a Clue: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT In young patients with hypertension or stroke, the presence of bilateral parvus et tardus waveforms in the renal arteries should prompt reverse tracing to rule out aortic coarctation. This simple ultrasound clue enables early, non‐invasive screening and prevents missed diagnoses.
Yan‐li Chen, Jin‐hua Wang
wiley   +1 more source

Effect of renin-angiotensin-aldosterone system inhibitor and statin medication on periodontal status of patients at risk of cardiovascular disease: a systematic review and meta-analysis. [PDF]

Saudi Dent J
Khalilurrahman ZA, Anjani SK, Sulijaya B, Haerani N, Lessang R, Harsas NA, Rahdewati H.   +6 more
europepmc   +1 more source

Synergistic Effects of Normal‐Range Serum Sodium and Potassium on Mortality: The Modifying Role of Inflammation From a NHANES Cohort Analysis

Chronic Diseases and Translational Medicine, Volume 12, Issue 2, Page 139-150, June 2026.
Nonlinear associations of serum sodium levels with cardiovascular (A) and all‐cause mortality (B)among 32,837 adults. Nonlinear associations of serum potassium levels with cardiovascular (C) and all‐cause mortality (D) among 32,837 adults. ABSTRACT Background This study aimed to investigate the associations of serum sodium and potassium levels within ...
Haofeng Zhang, Fudong He, Zhenger Fang, Guangjun Zheng, Biying Zhou, Xia Chen, Mingliang Liu, Guang Hao   +7 more
wiley   +1 more source