Correction: Alpha-7 nicotinic acetylcholine receptor: targeting the interplay between inflammation, renin-angiotensin aldosterone system, and nervous system for the novel treatment of heart failure. [PDF]
Front PharmacolSwiderski J +6 more
europepmc +1 more source
Equine Veterinary Education, Volume 38, Issue 10, Page e676-e685, October 2026.Summary A 4‐year‐old, 6‐month pregnant, Welsh pony mare presented with severe acute clinical signs including depression, anorexia, pale mucous membranes, tachycardia with a grade 4/6 holosystolic murmur and moderate expiratory dyspnoea with diffuse wheezes. There was no evidence of placentitis or fetal distress.
M. F. David +4 more
wiley +1 more source
Before the Pressure Rises: Intrarenal Renin-Angiotensin-Aldosterone System Activation in Normotensive Autosomal Dominant Polycystic Kidney Disease. [PDF]
Kidney360Baker LW, Chebib FT.
europepmc +1 more source
ChemMedChem, Volume 21, Issue 17, 14 September 2026.A novel series of candidate AT1 receptor antagonists based on oxadiazolone‐triazole scaffolds was designed and synthesized. Most compounds reduced angiotensin II‐induced vascular contraction in an initial biological screening, with compound 7f emerging as the most active derivative.
Larissa F. L. Ferreira +5 more
wiley +1 more source
Perillyl alcohol attenuates hypoxia induced right ventricular dysfunction and remodeling by balancing the renin angiotensin aldosterone system in rats. [PDF]
Sci RepBai HJ +5 more
europepmc +1 more source
Progress in Synthesis and Pharmacology of Telmisartan
Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.Telmisartan is a benzimidazole derivative and a well‐known drug to treat hypertension. This review provides synthesis and understanding of telmisartan as an antihypertensive drug through two mechanisms of actions: RAAS inhibitor and PPARγ receptor. Effective repurposing of this drug for various diseases like chronic kidney illness, diabetes, fatty ...
Megha, Richa Srivastava, Ram Singh
wiley +1 more source
Is long-term disruption of the renin-angiotensin-aldosterone system associated with long COVID? A retrospective cohort study among healthcare workers. [PDF]
BMC Infect DisLange-Tal T +7 more
europepmc +1 more source
Revising NHE‐1: From Cardiac Homeostasis to Heart Failure and Future Drug Development
Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.ABSTRACT NHE‐1 is a Na+/H+ exchanger that receives phosphorylation signals, binds calmodulin and responds to neurohormonal input from angiotensin II, endothelin‐1, and adrenergic pathways. In cardiac myocytes, NHE‐1 maintains pH homeostasis and couples to Na+/Ca2+ exchange and mitochondrial ion handling. During heart disease sustained activation drives
Vasileios Bouratzis +8 more
wiley +1 more source
Correlation Between Activity Level of Renin-Angiotensin-Aldosterone System and Perfusion Index in Children with Postural Tachycardia Syndrome. [PDF]
Vasc Health Risk ManagZhang F, Pan J, Lin Z, Niu M.
europepmc +1 more source
Catheterization and Cardiovascular Interventions, Volume 108, Issue 3, Page 935-945, September 1, 2026.ABSTRACT Background Acute kidney injury (AKI) is associated with worse outcomes after percutaneous coronary intervention (PCI). Previous, smaller studies suggested nephroprotective effects of micro‐axial flow pump (mAFP) during PCI. This study aimed to compare renal outcomes of high‐risk PCI with mAFP or intraaortic balloon pump (IABP) support.
Elric Zweck +10 more
wiley +1 more source