Results 181 to 190 of about 80,731 (303)

Vasopressin and fluid retention after liver resection: Comparison with the renin-angiotensin-aldosterone system by surgical extent and liver function. [PDF]

World J Gastroenterol
Aoki Y, Kawano Y, Ga R, Endo K, Ueda J, Shimizu T, Yoshida H.   +6 more
europepmc   +1 more source

Leptin in Obesity‐Related Heart Failure: Pathophysiological Mechanisms and Therapeutic Implications

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Obesity‐associated adipose tissue dysfunction leads to hyperleptinemia and altered leptin signaling. Through Ob‐Rb/LepR‐mediated pathways, leptin may contribute to neurohormonal activation, endothelial dysfunction, inflammation, oxidative stress, and myocardial remodeling.
Xuemin Li, Weiguo Wang, Yibo Zhang, Pengfei Ding, Xuewen Li   +4 more
wiley   +1 more source

Dual Inhibition of the Renin-Angiotensin-Aldosterone System and Sodium-Glucose Cotransporter-2: Mechanistic and Clinical Evidence for Cardiorenal Protection. [PDF]

Biomedicines
Aazar RFM, Arzouni R, Nicolaou PA.
europepmc   +1 more source

Pharmacokinetic Drug–Drug Interaction Potential of Oral Anticancer Drugs

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1614-1627, June 2026.
Drug–drug interaction (DDI) management is critical for safe and effective use of oral anticancer drugs (OADs). Our study objectives were to (i) compile clinically relevant pharmacokinetic (PK) DDI mechanisms for OADs and (ii) assess the prevalence of PK potential DDIs (PDDIs) in patients with advanced solid cancers.
Fatimah Alhurayri, Islam R. Younis, Shadia I. Jalal, Theodore F. Logan, Rohan Maniar, Steven M. Bray, Sara K. Quinney, Zeruesenay Desta, Todd C. Skaar, James E. Tisdale, Tyler Shugg   +10 more
wiley   +1 more source

Correction: Alpha-7 nicotinic acetylcholine receptor: targeting the interplay between inflammation, renin-angiotensin aldosterone system, and nervous system for the novel treatment of heart failure. [PDF]

Front Pharmacol
Swiderski J, Gadanec LK, Hearth S, Rowlands BD, Murphy AJ, Apostolopoulos V, Zulli A.   +6 more
europepmc   +1 more source

Impact of Prior Angiotensin‐Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Use on Delirium Incidence in ICU Patients: A Retrospective Study

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims This investigation aimed at exploring the impact that the pre‐existing use of angiotensin‐converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) has on the incidence of delirium in patients within the intensive care unit (ICU).
Zhe Li, Shuo Liu, Qihai Wan, Yahui Niu, Yi Yu   +4 more
wiley   +1 more source

Revisiting renin-angiotensin-aldosterone system in aging: translational insights from bench to bedside and back. [PDF]

J Clin Invest
Cosarderelioglu C, Abadir PM.
europepmc   +1 more source

Multi‐Layered Genomic and Clinical Analysis Identifies Novel Variants, Co‐Occurring Single Nucleotide Polymorphism Pairs, and Clinical Determinants of Host‐Pathogen Interaction in COVID‐19 Severity

Journal of Medical Virology, Volume 98, Issue 6, June 2026.
ABSTRACT Host genetic factors may contribute to COVID‐19 severity. To identify genetic variants influencing COVID‐19 severity progression, whole‐exome sequencing was performed, followed by an exome‐wide association study on 191 hospitalized patients categorized into three severity groups.
Doris Repušić, Marina Korolija, Ana Livun, Tomo Svaguša, Robert Belužić, Vjekoslav Tomaić, Rosa Karlić, Kristian Vlahoviček   +7 more
wiley   +1 more source

Before the Pressure Rises: Intrarenal Renin-Angiotensin-Aldosterone System Activation in Normotensive Autosomal Dominant Polycystic Kidney Disease. [PDF]

Kidney360
Baker LW, Chebib FT.
europepmc   +1 more source

The Efficacy of Left Atrial Appendage Occlusion During Thoracoscopic Epicardial AF Ablation for Improving Rhythm and Cardiac Function in Patients With Heart Failure

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
Thoracoscopic epicardial AF ablation in heart failure improved LV systolic function irrespective of left atrial appendage occlusion (LAAO). Concomitant surgical LAAO was associated with fewer LPV reconnections without worsening postoperative diastolic function, while atrial tachyarrhythmia recurrence was similar between groups.
Seongjin Park, Dong Seop Jeong, Jiwon Kim, Myoung Jung Kim, Juwon Kim, Seung‐Jung Park, Kyoung‐Min Park, Young Keun On, Ju Youn Kim   +8 more
wiley   +1 more source