ABSTRACT Wild Laurus nobilis fruits, a well‐known dietary plant, have been documented to alleviate cardiopathy associated with pulmonary fibrosis, but the underlying mechanisms remain largely unspecified. This current study aimed to investigate the potential therapeutic effects of wild L.
Saber Jedidi +5 more
wiley +1 more source
The Emerging Role of Aldosterone Synthase Inhibitors in Overcoming Renin-Angiotensin-Aldosterone System Therapy Limitations: A Narrative Review. [PDF]
Patel SK +4 more
europepmc +1 more source
Abstract Background Although previous experimental studies showed that metabolic acidosis promoted muscle catabolism and impaired protein synthesis, few epidemiological studies reported an independent association between serum bicarbonate levels and muscle atrophy in patients with chronic kidney disease (CKD).
Nobuhisa Morimoto +13 more
wiley +1 more source
Renin-Angiotensin-Aldosterone System Profiling in Horses Before and After Exercise. [PDF]
Holbrook T +6 more
europepmc +1 more source
Current Status of Kidney Xenotransplantation in Basic Research
Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley +1 more source
Alpha-7 nicotinic acetylcholine receptor: targeting the interplay between inflammation, renin-angiotensin aldosterone system, and nervous system for the novel treatment of heart failure. [PDF]
Swiderski J +6 more
europepmc +1 more source
The Boruta‐XGBoost based risk prediction model, combined with SHAP interpretation, demonstrated high predictive accuracy and robust interpretability for forecasting hospital readmission or death during the vulnerable phase in elderly heart failure patients. This model can assist clinicians to identify high‐risk individuals, supporting clinical decision‐
Hao Luo +10 more
wiley +1 more source
Hypertension in obstructive sleep apnea: the hidden role of renin-angiotensin-aldosterone system dysregulation. [PDF]
Loh HH +11 more
europepmc +1 more source
ABSTRACT Aim Myocardial infarction (MI) is one of the leading causes of death worldwide. MI is associated with cardiac structural and functional alterations. Among these, cardiac fibrosis may be significantly influenced by mitochondrial dysfunction. We sought to evaluate whether the injection of functional mitochondria from healthy muscle could improve
María Cuesta‐Corral +13 more
wiley +1 more source
Renin-angiotensin aldosterone system inhibitors usage among hospitalized patients with acute kidney injury: a retrospective study. [PDF]
Xu L +5 more
europepmc +1 more source

