Results 211 to 220 of about 52,295 (246)
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Pathologic hypofunction of the renin-angiotensin-aldosterone system
Postgraduate Medicine, 1976The literature now contains reports of many cases of aldosterone deficiency. Usually, the presenting features are persistent hyperkalemia and tendencies to serious urinary sodium loss and hypotension. A classification of defects leading to pathologic hypofunction of the renin-angiotensin-aldosterone system (RAAS hypofunction) is presented, with ...
J N, Priest, M, Ahmed, F Q, Nuttall
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Drugs targeting the renin–angiotensin–aldosterone system
Nature Reviews Drug Discovery, 2002Effective antihypertensive therapy has made a major contribution to the reductions in the morbidity and mortality of cardiovascular disease that have been achieved since the 1960s. However, blood-pressure control with conventional drugs has not succeeded in reducing cardiovascular disease risks to levels seen in normotensive persons. Drugs that inhibit
Mohammad Amin, Zaman +2 more
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Renin-Angiotensin-Aldosterone System
Abstract Renin-angiotensin-aldosterone systems exist in various tissues throughout the body, including the kidneys, adrenal gland, cardiovascular system, and nervous system, where it may be involved in local regulation of vascular tone. Renin causes angiotensin to be cleaved into angiotensin I, which is then converted to angiotensin II ...Marwa El-Sabbahy, Karim Fikry
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Therapeutic inhibition of the renin angiotensin aldosterone system
Expert Opinion on Therapeutic Patents, 2009Inhibitors of the renin angiotensin aldosterone system (RAAS) represent some of the most widely prescribed, successful and well-tolerated therapeutics of recent times and are of proven worth in the management/prevention of cardiovascular disease and diabetic nephropathy. However, as knowledge has grown about the RAAS and its manifold alternate pathways,
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Novel aspects of the renin-angiotensin-aldosterone-system
Frontiers in Bioscience, 2008The renin-angiotensin-aldosterone system (RAAS) play a pivotal role in the progression of renal disease. The RAAS has become much more complex in recent years with the identification of novel peptides that exhibit biological activity. There are novel pathways of angiotensin II (ANG II) generation independent of angiotensin converting enzyme (ACE).
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The Interplay Between the Renin-Angiotensin-Aldosterone System and Parathyroid Hormone
Frontiers in Endocrinology, 2020Feng Xu, Ling-Qing Yuan, Xiao Lin
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