Based on the validity of instrumental variable assumptions, our Mendelian randomization analysis revealed that genetic predisposition to major depression was associated with an increased risk of arrhythmias and suggested potential bidirectional effects between major depression and atrioventricular block. ABSTRACT Major depression, bipolar disorder, and
Jingyang Su +3 more
wiley +1 more source
Impact of Renin-Angiotensin-Aldosterone System (RAAS) Gene Polymorphism in Essential Hypertension and Antihypertensive Drug Therapy: A Review. [PDF]
Adhikari A +5 more
europepmc +1 more source
Impaired aldosterone response to potassium and hyperkalemia in patients receiving a renin-angiotensin-aldosterone system inhibitor. [PDF]
Kim M, Lee HY, Kim H.
europepmc +1 more source
Abstract Background Chronic kidney disease (CKD) is a significant public health challenge in Australia, affecting ~10% of the adult population and contributing to substantial morbidity and mortality. Diabetes, hypertension, cardiovascular disease and CKD frequently co‐exist; therefore, a multidisciplinary approach is necessary to manage these ...
M. P. Schlaich +7 more
wiley +1 more source
Renal Function and the Role of the Renin-Angiotensin-Aldosterone System (RAAS) in Normal Pregnancy and Pre-Eclampsia. [PDF]
Tsikouras P +16 more
europepmc +1 more source
Associations of Long‐Term Blood Pressure Burden and Variability With Kidney Function Decline
ABSTRACT Long‐term blood pressure (BP) burden and visit‐to‐visit BP variability may better capture cumulative hemodynamic stress on the kidneys than single‐visit BP measurements, yet evidence linking these metrics with kidney function decline in the general population remains limited.
Sisi Xie +3 more
wiley +1 more source
Latent Intrarenal Renin-Angiotensin-Aldosterone System Activation Could Persist Until Early School-Aged in Children with a History of Low Birth Weight. [PDF]
Ishimori S +13 more
europepmc +1 more source
ABSTRACT Carotid–femoral pulse‐wave velocity (cfPWV) is a marker of central arterial stiffness and an established predictor of cardiovascular risk in hypertension. Although elevated lipoprotein(a) [Lp(a)] concentrations and peripheral arterial disease (PAD) are associated with atherosclerotic cardiovascular disease, their independent associations with ...
Bibombe P. Mwipatayi +8 more
wiley +1 more source
Effect of furosemide on comprehensive renin-angiotensin-aldosterone system activity of Thoroughbred horses. [PDF]
Lehman ML +3 more
europepmc +1 more source
A Clinical Prediction Model for Selective NT‐proBNP Testing in Hypertension
ABSTRACT N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) testing is recommended for pre‐heart failure (pre‐HF) screening. However, universal NT‐proBNP testing is infeasible and inefficient. We analyzed data from 4642 U.S. adults with hypertension in NHANES 1999–2004.
Anping Cai +6 more
wiley +1 more source

