Results 251 to 260 of about 80,731 (303)

Targeting the Renin-angiotensin-aldosterone System (RAAS) for Cardiovascular Protection and Enhanced Oncological Outcomes: Review. [PDF]

open access: yesCurr Treat Options Oncol
Pawlonka J   +5 more
europepmc   +1 more source

Dysfunction of the renin-angiotensin-aldosterone system in human septic shock. [PDF]

open access: yesPeptides
Schaich CL   +5 more
europepmc   +1 more source

The Renin-Angiotensin-Aldosterone System and Heart Failure

Cardiology Clinics, 2014
The renin-angiotensin-aldosterone system (RAAS) plays a critical role in the pathophysiology of heart failure with reduced ejection fraction (HFrEF). Targeting components of the RAAS has produced significant improvements in morbidity and mortality. Angiotensin-converting enzyme (ACE) inhibitors remain first-line therapy for all patients with a reduced ...
Gabriel Sayer, Geetha Bhat
exaly   +3 more sources

The Renin-Angiotensin-Aldosterone System in Podocytes

Seminars in Nephrology, 2012
The renin-angiotensin-aldosterone system (RAAS) plays a critical role in kidney function and its inhibition reduces proteinuria and preserves kidney function in patients with chronic kidney disease. Recent studies have shown that podocytes generate many components of the RAAS and they express receptors of RAAS, including angiotensin II ...
Dirk Oliver, Wennmann   +2 more
openaire   +2 more sources

Obesity and the renin– angiotensin–aldosterone system

Expert Review of Endocrinology & Metabolism, 2006
The renin-angiotensin-aldosterone system (RAAS) is a key regulator of cardiovascular function. RAAS activity is upregulated in obesity despite concurrent renal sodium retention, which is a hallmark and principle determinant of obesity-associated hypertension.
Arya M, Sharma, Stefan, Engeli
openaire   +2 more sources

The renin-angiotensin-aldosterone system

Klinische Wochenschrift, 1978
"The present results indicate that there is a close relationship between the incretory function of the kidney, which is shown by the discharge of renin and similar materials, and the function of the adrenal cortex, especially the zona glomerulosa, which is the place of production of the sodium-retaining hormone aldosterone .
P, Vecsei, E, Hackenthal, D, Ganten
openaire   +4 more sources

Adrenomedullin and the renin–angiotensin–aldosterone system

Regulatory Peptides, 2003
Despite its positive inotropic effects and its propensity to stimulate the renin system, adrenomedullin (AM) is hypotensive as a result of dramatic reductions in peripheral resistance. Furthermore, it does not appear to increase aldosterone secretion in spite of often vigorous activation of circulating renin.
Christopher J, Charles   +5 more
openaire   +2 more sources

Renin-Angiotensin-Aldosteron-System und Fibrinolyse

Medizinische Klinik, 2000
Experimental, genetic and clinical evidence suggests that the renin-angiotensin-aldosterone system (RAAS) may participate in the pathogenesis of thromboembolic cardiovascular disorders such as coronary heart disease. This interrelationship may involve mechanisms other than changes in arterial blood pressure. In addition to various possible interactions,
K, Lottermoser   +3 more
openaire   +2 more sources

Hypertension and the Renin–Angiotensin–Aldosterone System

2018
Hypertension is defined as a systolic blood pressure > 140 mmHg or a diastolic blood pressure > 90 mmHg. Renin is a key enzyme of the renin-angiotensin-aldosterone system (RAAS), cleaving angiotensinogen to angiotensin I and, thereby, having an impact on the synthesis rate of the effector hormone of the RAAS, angiotensin II. The RAAS is a hormone
Kaschina, Elena   +2 more
openaire   +3 more sources

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