Results 81 to 90 of about 86,752 (290)
Dipeptidyl peptidase 3, a marker of the antagonist pathway of the renin–angiotensin–aldosterone system in patients with heart failure [PDF]
, 2021 Eva M. Boorsma +10 more
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Laborbeurteilung des Renin-Angiotensin-Aldosteron-Systems
, 2021 The renin-angiotensin-aldosterone-system or RAAS is one of the most important, endogenous systems for maintaining homeostasis of electrolytes, body fluid level and blood pressure. Many diseases stemming from dysregulation in the RAAS become symptomatic by derailment of electrolytes or blood pressure.
openaire +2 more sources
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Excess adiposity and obesity are increasingly prevalent, with incidence rising in many parts of the world; both trigger a state of metabo‐inflammation in adipose tissue, creating a systemic milieu characterised by insulin resistance and pro‐inflammatory and fibrogenic states. Along with systemic inflammatory cues, perturbations in systemic and
Mirjana Grocic +2 more
wiley +1 more source
Fibroblast growth factor 23 is induced by an activated renin–angiotensin–aldosterone system in cardiac myocytes and promotes the pro-fibrotic crosstalk between cardiac myocytes and fibroblasts [PDF]
, 2018 Maren Leifheit‐Nestler +7 more
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The FEBS Journal, EarlyView.Angiotensin I‐converting enzyme (ACE) contains two catalytic domains (nACE and cACE) and is a key therapeutic target for hypertension and cardiovascular disease. Current ACE inhibitors (ACEi) nonselectively inhibit both domains, causing adverse effects. Selective inhibition requires an understanding of domain‐specific binding.
Kyle S. Gregory +3 more
wiley +1 more source
The behavior of renal-regulating hormones during hypogravic stress [PDF]
The regulation of fluid and electrolyte behavior during space flight is believed to be under control, in large part, of a group of hormones which have their major effects on renal excretion. The hormones studied include renin-angitensin, aldosterone, and
Leonard, J. I.
core +1 more source
RESPONSE OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM TO FUROSEMIDE AND ACUTE SALT LOADING IN THE FETAL LAMB [PDF]
, 1977 Sharon R Siegel +2 more
openalex +1 more source
Hepatology Research, EarlyView.Mineralocorticoid receptor antagonists are known to reduce proteinuria in chronic kidney disease, but their effectiveness in preventing bevacizumab‐related proteinuria has not been well established. In the present multi‐institutional retrospective study, we found that these agents significantly delay the onset of moderate or higher grade proteinuria ...
Tomoki Hori +17 more
wiley +1 more source
Resistant hypertension and renal denervation: Who's kidding whom? [PDF]
, 2014 Sever, P
core +1 more source
Internal Medicine Journal, EarlyView.Abstract Background Chronic kidney disease (CKD) is a significant public health challenge in Australia, affecting ~10% of the adult population and contributing to substantial morbidity and mortality. Diabetes, hypertension, cardiovascular disease and CKD frequently co‐exist; therefore, a multidisciplinary approach is necessary to manage these ...
M. P. Schlaich +7 more
wiley +1 more source