Results 101 to 110 of about 217,588 (352)

Evaluating Molecular Mechanism of Hypotensive Peptides Interactions with Renin and Angiotensin Converting Enzyme

open access: yesPLoS ONE, 2014
Our previous study showed that three rapeseed protein-derived peptides (TF, LY and RALP) inhibited the in vitro activities of angiotensin converting enzyme (ACE) and renin.
Rong He, R. Aluko, Xingrong Ju
semanticscholar   +1 more source

Socio‐economic status and the effect of guideline‐directed medical therapy in the STRONG‐HF study

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Acute heart failure (AHF) impacts millions globally, with outcomes varying based on socio‐economic status (SES). Methods SES measured by annual household income, years of education and medical insurance coverage. Each patient's income and education level relative to the median or mean, respectively, in the country was calculated, and ...
Albertino Damasceno   +29 more
wiley   +1 more source

Guideline‐directed medical therapy in patients undergoing transcatheter edge‐to‐edge repair for secondary mitral regurgitation

open access: yesEuropean Journal of Heart Failure, Volume 24, Issue 11, Page 2152-2161, November 2022., 2022
Triple guideline‐directed medical therapy (GDMT) prescription was associated with a lower 2‐year mortality compared to non‐triple GDMT prescription (A). Such association was observed in patients with concomitant comorbidities (B). CI, confidence interval; CKD, chronic kidney disease; CMP, cardiomyopathy; HR, hazard ratio; MRA, mineralocorticoid ...
Satoshi Higuchi   +36 more
wiley   +1 more source

Renin-angiotensin-aldosteron system: evolution of views from renin discovery to nowadays. Perspectives of therapeutic block

open access: yesТерапевтический архив, 2011
Recent revolution in the knowledge about structure, physiological and pathophysiological effects of renin-angiotensin-aldosteron system (RAAS) took place recently when it was discovered that local synthesis of all the RAAS components occurs in target ...
Marina Vladimirovna Shestakova   +1 more
doaj  

Efficacy and safety of dual blockade of the renin-angiotensin system: meta-analysis of randomised trials

open access: yesBritish medical journal, 2013
Objective To compare the long term efficacy and adverse events of dual blockade of the renin-angiotensin system with monotherapy. Design Systematic review and meta-analysis.
Harikrishna Makani   +4 more
semanticscholar   +1 more source

Use of guideline‐recommended medical therapy in patients with heart failure and chronic kidney disease: from physician's prescriptions to patient's dispensations, medication adherence and persistence

open access: yesEuropean Journal of Heart Failure, Volume 24, Issue 11, Page 2185-2195, November 2022., 2022
Patients with heart failure and chronic kidney disease are less likely to receive and persist on guideline‐recommended medical therapies. Aim Half of heart failure (HF) patients have chronic kidney disease (CKD) complicating their pharmacological management.
Roemer J. Janse   +9 more
wiley   +1 more source

The Renin-Angiotensin Aldosterone System: Pathophysiological Role and Pharmacologic Inhibition

open access: yesJournal of Managed Care Pharmacy, 2007
BACKGROUND: The renin-angiotensin aldosterone system (RAAS) is a hormonal cascade that functions in the homeostatic control of arterial pressure, tissue perfusion, and extracellular volume.
S. Atlas
semanticscholar   +1 more source

Serum Renin and Renin Substrate Levels in Scleroderma

open access: yesExperimental Biology and Medicine, 1975
Scleroderma is a disease of mesenchymal tissues characterized by fibrosis and vascular changes which eventually lead to organ insufficiency. Two clinical forms have been recognized, localized and systemic scleroderma. The localized form only affects the skin and the lesions have a tendency to resolve spontaneously. Systemic scleroderma is a progressive,
Anne B. Gould, Raul Fleischmajer
openaire   +3 more sources

Duration of sodium zirconium cyclosilicate treatment and continuation of RAASi therapy after a hyperkalaemia episode

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Renin–angiotensin–aldosterone system inhibitors (RAASi) are foundational in the management of heart failure (HF) and chronic kidney disease (CKD) but increase the risk of hyperkalaemia. To facilitate continuation of RAASi therapy, guidelines suggest managing hyperkalaemia using newer potassium binders such as sodium zirconium ...
Charles V. Pollack Jr.   +9 more
wiley   +1 more source

Evolution of tricuspid regurgitation after transcatheter edge‐to‐edge mitral valve repair for secondary mitral regurgitation and its impact on mortality

open access: yesEuropean Journal of Heart Failure, Volume 24, Issue 11, Page 2175-2184, November 2022., 2022
Aim To evaluate short‐term changes in tricuspid regurgitation (TR) after transcatheter edge‐to‐edge mitral valve repair (M‐TEER) in secondary mitral regurgitation (SMR), their predictors and impact on mortality. Methods and results This is a retrospective analysis of SMR patients undergoing successful M‐TEER (post‐procedural mitral regurgitation ≤2 ...
Marianna Adamo   +41 more
wiley   +1 more source

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