Results 91 to 100 of about 163,477 (306)

Local renin-angiotensin system regulates left ventricular hypertrophy induced by swimming training independent of circulating renin: a pharmacological study

, 2009
Introduction. This study addressed the role of the local renin-angiotensin system (RAS) in the left ventriular hypertropy (LVH) induced by swimming training using pharmacological blockade. Materials and methods.
CERENCIO, Marcela, OLIVEIRA, Edilamar M., KRIEGER, Jose E., SASAKI, Mauricio S., BARAUNA, Valerio G.   +4 more
core   +1 more source

Analysis of the usefulness and benefits of ultrafiltration in cardiorenal syndrome: A systematic review

ESC Heart Failure, Volume 12, Issue 2, Page 1194-1202, April 2025.
Abstract Aims Cardiac decompensation in cardiorenal syndrome (CRS) results in systemic congestion usually treated with diuretics. When despite high doses of diuretics, response is poor, ultrafiltration (UF) appears to be a useful and safe technique.
Borja Guerrero Cervera, Raquel López‐Vilella, Víctor Donoso Trenado, María Peris‐Fernández, Paula Carmona, Amparo Soldevila, Sergi Tormo, Ramón Devesa, María Jesús Montero Hernández, Luis Martínez Dolz, Julio Hernández Jaras, Pilar Sánchez‐Pérez, Luis Almenar‐Bonet   +12 more
wiley   +1 more source

Bimodal dynamics of granular organelles in primary renin-expressing cells revealed using TIRF microscopy [PDF]

, 2017
Renin is the initiator and rate-limiting factor in the renin-angiotensin blood pressure regulation system. Although renin is not exclusively produced in the kidney, in nonmurine species the synthesis and secretion of the active circulatory enzyme is ...
Dun, Alison R., Buckley, Charlotte, Bellamy, Christopher, Peter, Audrey, Mullins, John J., Duncan, Rory R., Gross, Kenneth W.   +6 more
core   +1 more source

Diagnosis and management of primary aldosteronism

Archives of Endocrinology and Metabolism
Primary aldosteronism (PA) is the most common form of secondary hypertension (HTN), with an estimated prevalence of 4% of hypertensive patients in primary care and around 10% of referred patients. Patients with PA have higher cardiovascular morbidity and
Leticia A. P. Vilela, Madson Q. Almeida
doaj   +1 more source

Local Hematopoietic Renin-Angiotensin System in Myeloid Versus Lymphoid Hematological Neoplastic Disorders

, 2013
There is preliminary evidence that the local renin-angiotensin system (RAS) could affect neoplastic hematopoiesis. The aim of this study is to search messenger RNA (mRNA) expressions of the essential RAS elements in myeloid and lymphoid hematological ...
Sayinalp, Nilgun, Goker, Hakan, Ng, Ozden Hatirnaz, Aksu, Salih, Haznedaroglu, Ibrahim C., Buyukasik, Yahya, Tatonyan, Suzin Catal, Ozcebe, Osman I., ÖZCEBE, OSMAN İLHAMİ, Erbilgin, Yucel, Ozbek, Ugur, Uz, Burak, Sayitoglu, Muge   +12 more
core   +1 more source

eGFR slope as predictor of mortality in heart failure patients

ESC Heart Failure, Volume 12, Issue 2, Page 1217-1226, April 2025.
Abstract Aims Heart failure (HF) leads to an imbalance between heart and kidney function, resulting in poor outcomes. However, the prognostic significance of the estimated glomerular filtration rate (eGFR) trajectory in HF patients remains unclear. We analysed electronic health records (EHRs) of real‐world HF patients, assessing eGFR trajectories and ...
Sofie Verstreken, Monika Beles, Clara L. Oeste, Ana Moya, Imke Masuy, Riet Dierckx, Ward Heggermont, Jeroen Dauw, Dries Hens, Jozef Bartunek, Marc Vanderheyden   +10 more
wiley   +1 more source

The effects of the renin-angiotensin-aldosterone system gene polymorphisms on insulin resistance in hypertensive families

, 2014
Introduction: The hereditability of insulin resistance has been demonstrated in both familial and twin studies. The effects of renin-angiotensin-aldosterone system gene polymorphisms on insulin resistance remain inconclusive.
Hsiao, Chin-Fu;Sheu, Wayne W. H.;Hung, Yi-Jen;Lin, Ming-Wei;Curb, David;Ranadex, Koustubh;Quertermous, Thomas;Chen, Yue-Ming;Chen, Ida Yi-Der;Wu, Kwan-Dun, 吳寬墩   +1 more
core   +1 more source

Epidemiology of hospitalized heart failure in France based on national data over 10 years, 2012–2022

ESC Heart Failure, Volume 12, Issue 2, Page 1283-1294, April 2025.
Abstract Aims We aim to describe the incidence of HF hospitalization in France in the post‐pandemic era, the prevalence of HF cases and patients' characteristics, management and outcomes while focusing on sex, age and socio‐economic differences and to analyse time‐trends between 2012 and 2022.
Valérie Olié, Richard Isnard, Françoise Pousset, Clémence Grave, Jacques Blacher, Amélie Gabet   +5 more
wiley   +1 more source

Design of New Inhibitory ligands Based on Bioenformatic Pharmacophore Modeling in Renin Enzyme for Blood Pressure Control and Treatment [PDF]

پیاورد سلامت
Background and Aim: One of the ways to control high blood pressure is to deactivate the renin-angiotensinogen-aldosterone RAAS system. Renin, also known as angiotensinogenase,It is a type of enzyme that is produced in the afferent arterioles of the ...
Saeed Pirmoradi
doaj  

Left atrial function in uraemic patients: Four‐dimensional automatic left atrial quantitative technology study

ESC Heart Failure, Volume 12, Issue 2, Page 1316-1325, April 2025.
Abstract Objective This study aimed to evaluate the utility of left atrial volume and function in uraemic patients using four‐dimensional automatic left atrial quantification (4D auto LAQ) technology. Methods Thirty‐four undialysed uraemic patients (U‐ND group), 60 dialysed uraemic patients (U‐D group), and 32 healthy volunteers (N group) were enrolled
Bing Li, Meihua Chen, Xuning Huang
wiley   +1 more source