Results 191 to 200 of about 261,257 (360)

Characteristics, therapeutic pathway and the economic burden of patients with drug‐resistant epilepsy: A real‐world analysis following the introduction of cenobamate in Italy

Epilepsia, EarlyView.
Abstract Objectives Drug‐resistant epilepsy (DRE) remains a major clinical challenge, affecting approximately one‐third of patients with epilepsy. Cenobamate, a novel antiseizure medication (ASM) approved in Italy in 2022, has shown promise in clinical trials. However, real‐world data on its use, especially economic evaluations, remain limited.
Valentina Perrone, Chiara Veronesi, Maria Cappuccilli, Margherita Andretta, Marcello Bacca, Antonietta Barbieri, Fausto Bartolini, Alessandro Brega, Maria Rosaria Cillo, Francesco Colasuonno, Stefania Dell'Orco, Fulvio Ferrante, Stefano Grego, Antonella Lavalle, Daniela Mancini, Maurizio Pastorello, Romina Pagliaro, Cataldo Procacci, Camilla Scandolara, Patrizia Schiavone, Loredana Ubertazzo, Paola Valpondi, Adriano Vercellone, Alberto Zucchi, Maria Ciappetta, Domenico Lucatelli, Andrea Cinti Luciani, Luca Degli Esposti   +27 more
wiley   +1 more source

Renal PIEZO2 is an essential regulator of renin. [PDF]

Cell
Hill RZ, Nelson JW, Gyarmati G, Medrano S, Shirvan S, McCormick JA, Burquez S, Ahmed J, Eng DG, Wysocki J, Dubin AE, Servin-Vences MR, Lakshmanan A, Gomez RA, Sequeira-Lopez MLS, Shankland SJ, Batlle D, Miner JH, Peti-Peterdi J, Patapoutian A.   +19 more
europepmc   +1 more source

Ocular renin-angiotensin system with special reference in the anterior part of the eye

, 2015
Mervi Holappa
openalex   +1 more source

Relationship between angiotensinogen, alpha-1-protease inhibitor elastase complex, antithrombin III and C-reactive protein in septic ARDS [PDF]

, 1990
Hilgenfeldt, U., Jochum, Marianne, Kellermann, W., Kienapfel, G.   +3 more
core   +1 more source

Persistent headache after aneurysmal subarachnoid hemorrhage: Prevalence, characteristics, and migraine history as a prognostic factor

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Persistent headache (PH) after an aneurysmal subarachnoid hemorrhage (aSAH) and the influence of migraine history (MH) on its evolution and prognosis is poorly understood. Our study aims are to (1) determine the prevalence, characteristics, and prognostic factors of PH after aSAH; and (2) study the impact of personal MH ...
Laura Gómez‐Dabó, Víctor J. Gallardo, Daniel Campos‐Fernández, Marc Rodrigo‐Gisbert, Maider Iza‐Achutegui, Anna Sánchez, Fuat Arikan, Estevo Santamarina, Edoardo Caronna, Patricia Pozo‐Rosich   +9 more
wiley   +1 more source

Structure-Based Design and In Silico Evaluation of a Lipophilic Cyclooctanoyl- Derivative as a Renin Inhibitor: Lessons from Withdrawn Aliskiren. [PDF]

Int J Mol Sci
Pavlos D, Petsas E, Chatzipieris FP, Mavromoustakos T, Chasapis CT.   +4 more
europepmc   +1 more source

Multiple databases analyzed the prognosis prediction of renin secretion pathway-related genes in renal clear cell carcinoma and immunotherapy

Hubo Li, Xinghua Bao, Yonggui Xiao, Fenghong Cao, Xiaoyan Han, Yansheng Zhao, Shaosan Kang   +6 more
openalex   +1 more source

Aggressive blood pressure reduction and renin–angiotensin system blockade in chronic kidney disease: time for re-evaluation? [PDF]

, 2013
Pantelis Sarafidis, Luís M. Ruilope
openalex   +1 more source

Sacubitril/Valsartan Attenuates Inflammation and Fibrosis Associated With Decreased Integrin α8 and Inhibits Hepatocarcinogenesis in a Rat Model of Metabolic Dysfunction‐Associated Steatohepatitis

Hepatology Research, EarlyView.
Sacubitril/Valsartan (Sac/Val) alleviates fibrosis and inflammation in metabolic dysfunction‐associated steatohepatitis (MASH). Its anti‐fibrotic effect is linked to the suppression of Integrin alpha 8 (Itga8), a protein crucial for hepatic stellate cell (HSC) activation and collagen production.
Hayato Kawamura, Aya Naiki‐Ito, Xiaochen Kuang, Akihiro Murakami, Masayuki Komura, Takanori Suzuki, Hiroyuki Kato, Yuko Nagayasu, Kentaro Matsuura, Kei Fujiwara, Hiromi Kataoka, Satoru Takahashi   +11 more
wiley   +1 more source

Quarterly injectable hormonal contraceptive does not increase the activity of the renin-angiotensin-aldosterone system in women without cardiovascular risk factors. [PDF]

Rev Bras Ginecol Obstet
de Oliveira AM, Dos Santos PA, Souza PES, do Sacramento MS, Souza CF, Ladeia AMT, Petto J.   +6 more
europepmc   +1 more source