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Reminiscences of Ervin G Erdös [PDF]

open access: yesScripta Medica, 2019
This article includes personal reminiscence of the great scientist Ervin G Erdös (1922-2019). Dr Erdös was born in Budapest, where he studied medicine. He finished his medical school in Munich, and obtained MD degree in 1952.
Igić Rajko
doaj  

Lack of direct evidence for a functional role of voltage-operated calcium channels in juxtaglomerular cells [PDF]

open access: yes, 1990
In this study we have examined the role of voltage-gated calcium channels in the regulation of calcium in juxtaglomerular cells. Using a combination of patch-clamp and single-cell calcium measurement we obtained evidence neither for voltage-operated ...
Chegini, S.   +3 more
core   +1 more source

A new common functional coding variant at the DDC gene change renal enzyme activity and modify renal dopamine function. [PDF]

open access: yes, 2019
The intra-renal dopamine (DA) system is highly expressed in the proximal tubule and contributes to Na+ and blood pressure homeostasis, as well as to the development of nephropathy.
Baker, Dewleen G   +15 more
core   +2 more sources

Aliskiren, enalapril, or aliskiren and enalapril in heart failure [PDF]

open access: yes, 2016
BACKGROUND Among patients with chronic heart failure, angiotensin-converting–enzyme (ACE) inhibitors reduce mortality and hospitalization, but the role of a renin inhibitor in such patients is unknown.
]   +15 more
core   +5 more sources

Aldosterone status associates with insulin resistance in patients with heart failure-data from the ALOFT study [PDF]

open access: yes, 2009
<b>Background</b>: Aldosterone plays a key role in the pathophysiology of heart failure. In around 50% of such patients, aldosterone 'escapes' from inhibition by drugs that interrupt the renin-angiotensin axis; such patients have a worse ...
Connell, J.M.C.   +8 more
core   +1 more source

Changes in renal WT-1 expression preceding hypertension development [PDF]

open access: yes, 2016
Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica   +8 more
core   +2 more sources

Renin-Angiotensin System [PDF]

open access: yesNew England Journal of Medicine, 1975
ALTHOUGH the names of Tigerstedt and Bergman1 are associated with the first description in 1898 of renin extracted from the kidney, it may come as a surprise that when Tigerstedt, who was the senior worker in the partnership and the Professor of Physiology in the Karolinska Institute, Stockholm, died, there was no mention of renin in the various ...
openaire   +3 more sources

Feeding pregnant ewes a high-salt diet or saltbush suppresses their offspring’s postnatal renin activity

open access: yesAnimal, 2009
If ewes consumed a high-salt diet or saltbush during the last 3 months of pregnancy and for 3 weeks after birth, we expected the renin activity of their lamb to be suppressed at birth and at 3 weeks of age.
M.A. Chadwick   +3 more
doaj   +1 more source

Kinetics of the inhibition of renin and angiotensin I-converting enzyme by cod (Gadus morhua) protein hydrolysates and their antihypertensive effects in spontaneously hypertensive rats

open access: yesFood & Nutrition Research, 2015
Background: Cod muscle has a balanced protein profile that contains potentially bioactive amino acid sequences. However, there is limited information on release of these peptides from the parent proteins and their ability to modulate mammalian blood ...
Abraham T. Girgih   +5 more
doaj   +1 more source

Pharmacological effects of raas blockade in ischemic nephropathy [PDF]

open access: yes, 2016
Background: The management of ischemic nephropathy due to atherosclerotic renal artery stenosis has become increasingly conservative in the modern era, with current guidelines recommending optimized medical therapy as the initial step.
Barbano, Biagio   +8 more
core   +1 more source

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