Plasma Angiotensin II Is Increased in Critical Coronavirus Disease 2019
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) employs angiotensin-converting enzyme 2 (ACE2) as its receptor for cell entrance, and studies have suggested that upon viral binding, ACE2 catalytic activity could be inhibited; therefore ...
Rafael L. Camargo +20 more
doaj +1 more source
“Nomen not est omen”: the (pro)renin receptor and receptor-mediated endocytosis in the proximal tubule—a new (pro)renin-independent role forATP6ap2 [PDF]
Jörg Peters
openalex +1 more source
Angiotensin II: a new therapeutic option for vasodilatory shock
Rachel L Bussard,1 Laurence W Busse2,3 1Critical Care Pharmacy Specialist, Department of Pharmacy, Emory St Joseph’s Hospital, Atlanta, GA, USA; 2Department of Critical Care, Emory St Joseph’s Hospital, Atlanta, GA, USA; 3Division of ...
Bussard RL, Busse LW
doaj
Aldosterone status associates with insulin resistance in patients with heart failure-data from the ALOFT study [PDF]
<b>Background</b>: Aldosterone plays a key role in the pathophysiology of heart failure. In around 50% of such patients, aldosterone 'escapes' from inhibition by drugs that interrupt the renin-angiotensin axis; such patients have a worse ...
Connell, J.M.C. +8 more
core +1 more source
To explore the clinical features of coexisting primary aldosteronism (PA) and renal artery stenosis (RAS), we retrospectively analyzed records from 71 patients with PA with RAS and a control group of 121 patients with PA without RAS. Aldosterone-to-renin
Lin Zhao +8 more
doaj +1 more source
Background: The renin angiotensin aldosterone system (RAAS) plays a vital role in regulating glucose metabolism and blood pressure, electrolyte and fluid homeostasis.
Zohreh Rahimi +2 more
doaj
The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management [PDF]
Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia,
Raj, Satish R
core +1 more source
The effect of a multidisciplinary weight loss program on renal circadian rhythm in obese adolescents
Adolescent obesity is a serious health problem associated with many comorbidities. Obesity-related alterations in circadian rhythm have been described for nocturnal blood pressure and for metabolic functions.
Bruneel, Elke +8 more
core +1 more source
Differential renal effects of candesartan at high-and ultra-high doses in diabetic mice: potential role of ACE2/AT2R/Mas [PDF]
High doses of Ang II receptor (AT1R) blockers (ARBs) are renoprotective in diabetes. Underlying mechanisms remain unclear. We evaluated whether high/ultra-high doses of candesartan (ARB) up-regulate angiotensin-converting enzyme 2 (ACE2)/Ang II type 2 ...
Antunes, Tayze +10 more
core +1 more source
Effect of active vitamin D on renin in renal tubular epithelial cells under high glucose conditions
Objective To explore the effect of active vitamin D on renin, (pro) renin receptor (PRR) and NF-κB in rat renal tubular epithelial (NRK-52E) cells in high glucose conditions and elucidate the role of NF-κB.
Yi-qing He +4 more
doaj +1 more source

