Results 81 to 90 of about 221,319 (346)
Терапевтический архив, 2011 Recent revolution in the knowledge about structure, physiological and pathophysiological effects of renin-angiotensin-aldosteron system (RAAS) took place recently when it was discovered that local synthesis of all the RAAS components occurs in target ...
Marina Vladimirovna Shestakova +1 more
doaj
Mineralocorticoid hypertension
Indian Journal of Endocrinology and Metabolism, 2011 Hypertension affects about 10 - 25% of the population and is an important risk factor for cardiovascular and renal disease. The renin-angiotensin system is frequently implicated in the pathophysiology of hypertension, be it primary or secondary.
Vishal Gupta
doaj +1 more source
Roles of the circulating renin-angiotensin-aldosterone system in human pregnancy.
American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 2014 This review describes the changes that occur in circulating renin-angiotensin-aldosterone system (RAAS) components in human pregnancy. These changes depend on endocrine secretions from the ovary and possibly the placenta and decidua.
E. Lumbers, K. Pringle
semanticscholar +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Vasoplegic syndrome (VS) is a common complication after cardiac surgery with cardiopulmonary bypass (CPB). The main pathophysiology mechanism of VS includes a systemic inflammatory response syndrome due to surgical trauma, release of pro‐inflammatory mediators caused by blood contact with foreign surfaces of heart‐lung machine (pump and tubing)
Matteo Lucchelli +3 more
wiley +1 more source
Collecting duct-specific knockout of renin attenuates angiotensin II-induced hypertension.
AJP - Renal Physiology, 2014 The physiological and pathophysiological significance of collecting duct (CD)-derived renin, particularly as it relates to blood pressure (BP) regulation, is unknown.
N. Ramkumar +5 more
semanticscholar +1 more source
Epigenetic Changes Related to Hypertension in Asian Adults: A Systematic Review
Chronic Diseases and Translational Medicine, EarlyView.PRISMA study flow diagram. ABSTRACT Background Elevated high blood pressure is controlled by complicated, little‐understood genetic and epigenetic pathways that are influenced by both heritable and environmental variables. Many adult systolic and diastolic blood pressure‐related genomic loci have been identified through previous genome‐wide association
Lilik Sukesi +7 more
wiley +1 more source
PLoS ONE, 2014 Our previous study showed that three rapeseed protein-derived peptides (TF, LY and RALP) inhibited the in vitro activities of angiotensin converting enzyme (ACE) and renin.
Rong He, R. Aluko, Xingrong Ju
semanticscholar +1 more source
Autopsy findings in cases of fatal COVID‐19 vaccine‐induced myocarditis
ESC Heart Failure, EarlyView.Abstract COVID‐19 vaccines have been linked to myocarditis, which, in some circumstances, can be fatal. This systematic review aims to investigate potential causal links between COVID‐19 vaccines and death from myocarditis using post‐mortem analysis.
Nicolas Hulscher +3 more
wiley +1 more source
Inhibition of renin and the (pro)renin receptor system
Blood Pressure, 2012 Renin is the rate-limiting step of the renin-angiotensin system (RAS) and can induce hypertension and cardiovascular diseases (CVDs) through the over-activated renin-angiotensin-converting enzyme (ACE)-angiotensin (Ang) II-Ang II type 1 receptor (AT(1)R) axis.
Robert D. Phillips +3 more
openaire +3 more sources
The Renin-Angiotensin Aldosterone System: Pathophysiological Role and Pharmacologic Inhibition
Journal of Managed Care Pharmacy, 2007 BACKGROUND: The renin-angiotensin aldosterone system (RAAS) is a hormonal cascade that functions in the homeostatic control of arterial pressure, tissue perfusion, and extracellular volume.
S. Atlas
semanticscholar +1 more source