Comparison between screening for primary aldosteronism with and without drug adjustment
Blood PressureObjective Few studies have evaluated the performance of non-drug-adjusted primary aldosteronism (PA) screening. Therefore, we aimed to examine the consistency between PA screening results with and without drug adjustment and to explore the effectiveness ...
Yanlong Hua, Qing He
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Frontiers in Pharmacology, 2019 The aim of this study was to characterize the role of local RAS (renin–angiotensin system) in the inflammatory response of normal (N) and diabetic (D) mice with periodontal disease (PD).
Sandra Helena Penha Oliveira +11 more
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Effects of empagliflozin on cardiorespiratory fitness and significant interaction of loop diuretics [PDF]
, 2018 The effects of empagliflozin on cardiorespiratory fitness in patients with type 2 diabetes mellitus (T2DM) and heart failure with reduced ejection fraction (HFrEF) are unknown.
Abbate +14 more
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RENIN ANGIOTENSIN SYSTEM IN THE CONTEXT OF RENIN, PRORENIN, AND THE (PRO)RENIN RECEPTOR
Reviews in Agricultural Science, 2013 Since the discovery of renin by Tigerstedt in 1898, the complex roles of the components of the renin angiotensin system (RAS)have been extensively studied. RAS is involved in maintaining the homeostasis of body fluids and thus regulates the blood pressure.Renin is the key regulatory enzyme of RAS that catalyzes its only substrate angiotensinogen into ...
Tsutomu Nakagawa +4 more
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Protein Kinase G Is Involved in Acute but Not in Long-Term Regulation of Renin Secretion
Frontiers in Pharmacology, 2019 Pharmacological inhibition of the renin–angiotensin–aldosterone system (RAAS) is, in combination with diuretics, the first-choice treatment for hypertension, although 10–20% of patients do not respond adequately.
Andrea Schramm +5 more
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Aldosterone status associates with insulin resistance in patients with heart failure-data from the ALOFT study [PDF]
, 2009 <b>Background</b>: Aldosterone plays a key role in the pathophysiology of heart failure. In around 50% of such patients, aldosterone 'escapes' from inhibition by drugs that interrupt the renin-angiotensin axis; such patients have a worse ...
Connell, J.M.C. +8 more
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Effect of Accessory Renal Arteries on Essential Hypertension and Related Mechanisms
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground This case‐control study aimed to determine whether there were differences between patients with essential hypertension with accessory renal arteries (ARAs) and those without ARAs.
Fengyuan Wu +9 more
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Neuro-hormonal effects of physical activity in the elderly. [PDF]
, 2013 Thanks to diagnostic and therapeutic advances, the elderly population is continuously increasing in the western countries. Accordingly, the prevalence of most chronic age-related diseases will increase considerably in the next decades, thus it will be ...
Allocca, E +12 more
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THE LIBERATION OF RENIN BY PERFUSION OF KIDNEYS FOLLOWING REDUCTION OF PULSE PRESSURE [PDF]
, 1940 K. G. Kohlstaedt, Irvine H. Page
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Diagnosis and management of primary aldosteronism
Archives of Endocrinology and MetabolismPrimary aldosteronism (PA) is the most common form of secondary hypertension (HTN), with an estimated prevalence of 4% of hypertensive patients in primary care and around 10% of referred patients. Patients with PA have higher cardiovascular morbidity and
Leticia A. P. Vilela, Madson Q. Almeida
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