Results 81 to 90 of about 261,257 (360)

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

Clinical Pharmacology &Therapeutics, EarlyView.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Remodeling of left ventricle in hypertensive patients with renal addition arteries: associations with renin level and glomerular filtration rate

Лечащий Врач, 2021
The article is devoted to analysis of relationship of left ventricular remodeling, plasma renin level, glomerular filtration rate in patients with arterial hypertension and renal additional arteries.
Yu. P. Red’ko, N. N. Gladkikh, A. V. Yagoda   +2 more
doaj  

Показатели вариабельности ритма сердца, активности ренина и содержания альдостерона в плазме крови при ренопаренхиматозной артериальной гипертензии

Архивъ внутренней медицины, 2011
In the pathogenesis of renal arterial hypertension an important role of the renin-angiotensin-aldosterone (RAAS) is confirmed. In addition to the humoral effects of the RAAS and blood pressure actively controls the vegetative nervous system (VNS ...
Н. Ю. Боровкова, Н. Н. Боровков, Е. О. Обухова, Ю. А. Хорькина, М. П. Нистратова, Б. Н. Сиднев, М. Ю. Серопян   +6 more
doaj   +1 more source

Significant correlation of angiotensin converting enzyme and glycoprotein IIIa genes polymorphisms with unexplained recurrent pregnancy loss in north of Iran [PDF]

, 2016
Background: Spontaneous abortion is considered as the most complex problem during pregnancy. Thrombophilia is resumed as a cause of recurrent pregnancy loss (RPL). Glycoprotein IIIa (GPIIIa) gene is involved in thrombosis and abortion.
Farazmandfar, T., Fazelnia, S., Hashemi-Soteh, S.M.B.   +2 more
core   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, EarlyView.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Association of insertion deletion polymorphism of the ACE gene with factors of circulating rennin-angiotensin-aldosterone system and endothelial function of skin microvassals in preeclampsia

Бюллетень сибирской медицины, 2011
The association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) gene polymorphism with plasma ACE, renin activity and endothelial function of skin microvassals were studied.
O. V. Radkov, M. N. Kalinkin, V. V. Zavarin   +2 more
doaj   +1 more source

Dipeptidyl peptidase 3, a marker of the antagonist pathway of the renin–angiotensin–aldosterone system in patients with heart failure [PDF]

, 2021
Eva M. Boorsma, Jozine M. ter Maaten, Kevin Damman, Dirk J. van Veldhuisen, Kenneth Dickstein, Stefan D. Anker, Gerasimos Filippatos, Chim C. Lang, Marco Metra, Karine Santos, Adriaan A. Voors   +10 more
openalex   +1 more source

Alterations in vascular function in primary aldosteronism - a cardiovascular magnetic resonance imaging study [PDF]

, 2014
Introduction: Excess aldosterone is associated with increased cardiovascular risk. Aldosterone has a permissive effect on vascular fibrosis. Cardiovascular magnetic resonance imaging (CMR) allows study of vascular function by measuring aortic ...
A McCurley, A Rudolph, A Tomaschitz, B Fink, B Strauch, B Strauch, C Catena, C Delles, C Delles, CB Stehr, D Rizzoni, DA Calhoun, E M Freel, E P McQuarrie, EM Freel, G Bernini, GE Callera, GF Mitchell, GP Rossi, JM Connell, JW Funder, K Gaddam, L U Zimmerli, LU Zimmerli, MJ van Trijp, MR Robinson, NC Edwards, OJ Rider, OJ Rider, P B Mark, P Milliez, P Rerkpattanapipat, PB Mark, R Holaj, R Rocha, RB Stacey, S Boyle, S Laurent, T Indra, WJ Rogers, YH Lin   +40 more
core   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Plasminogen Deficiency and Amiloride Mitigate Angiotensin II–Induced Hypertension in Type 1 Diabetic Mice Suggesting Effects Through the Epithelial Sodium Channel

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Diabetic nephropathy is a common diabetes mellitus complication associated with hypertension, proteinuria, and excretion of urinary plasmin that activates the epithelial sodium channel, ENaC, in vitro. Here we hypothesized that the deletion of
Henrik Andersen, Maria Høj Hansen, Kristian B. Buhl, Mette Stæhr, Ulla G. Friis, Camilla Enggaard, Shanya Supramaniyam, Ida K. Lund, Per Svenningsen, Pernille B. L. Hansen, Boye L. Jensen   +10 more
doaj   +1 more source