Results 111 to 120 of about 3,459,561 (335)

Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy.

, 2010
Rats harboring the human angiotensinogen and human renin genes develop preeclamptic features in pregnancy. The preeclamptic rats exhibit a deeper trophoblast invasion associated with a reduced resistance index by uterine Doppler.
Muller, DN, Cartwright, JE, Pijnenborg, R, Pijnenborg, R., Stefan Verlohren, Luft, F.C., Mueller, D.N., Lydia Hering, Morton, J., Davidge, ST, Dechend, R, Geusens, N, Robert Pijnenborg, Herse, F, Judith E. Cartwright, Herse, F., Florian Herse, Ralf Dechend, Dudenhausen, J.W., Nele Geusens, Cartwright, J.E., Geusens, N., Verhaegen, I., Jude Morton, Morton, J, Hering, L, Iris Verhaegen, Dominik N. Muller, Dechend, R., Sandra T. Davidge, Joachim W. Dudenhausen, Hering, L., Davidge, S.T., Verlohren, S, Verhaegen, I, Dudenhausen, JW, Friedrich C. Luft, Verlohren, S., Luft, FC   +38 more
core   +1 more source

Repurposing of renin inhibitors as SARS-COV-2 main protease inhibitors: A computational study. [PDF]

Virology, 2021
Refaey RH, El-Ashrey MK, Nissan YM.
europepmc   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Aliskiren ยาใหม่ในกลุ่ม Renin Inhibitors

, 2008
Aliskirenเป็นยาตัวแรกในกลุ่ม renin inhibitors ที่ได้รับการรับรองจากคณะกรรมการอาหารและยาประเทศสหรัฐอเมริกา เดือนมีนาคม ปี พ.ศ. 2550 ใช้สำหรับรักษาโรคความดันโลหิตสูงระดับอ่อนถึงปานกลาง โดยอาจใช้แบบเดี่ยว หรือใช้ร่วมกับยาลดความดันโลหิตสูงกลุ่มอื่น ๆ ...
ชนะกิจ, ธีราพร
core  

Renin-Angiotensin-aldosterone system inhibitors in heart failure

, 2013
Heart failure (HF) is a very common condition that, despite advances in treatment, carries significant morbidity and mortality. Although there is good evidence for the treatment of HF with reduced ejection fraction (HFrEF), the treatment for HF with ...
Struthers, A D, Lang, C C; id_orcid, Shearer, F   +2 more
core   +1 more source

Direct Inhibition of Renin

, 2021
From the beginning of the history of renin angiotensin system (RAS) with the renal extracts in 1898 it still continues to be exciting. After angiotensin converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARBs), direct renin inhibitors
Uresin, Yagiz, Ozunal, Zeynep Gunes
core   +1 more source

Practical Strategy for Treating Chronic Kidney Disease (CKD)-Associated with Hypertension

International Journal of Nephrology and Renovascular Disease, 2020
Daisuke Nagata, Erika Hishida, Takahiro Masuda Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Tochigi, JapanCorrespondence: Daisuke Nagata Tel +81 285 58 7346Fax +81 285 44 4869Email nagatad@jichi.ac.jpAbstract: When ...
Nagata D, Hishida E, Masuda T
doaj  

Functional Bread From Bambara Groundnut and Orange Peel Attenuates Hyperglycemia and Oxidative Stress in a High‐Fat Diet/Streptozotocin‐Induced Type 2 Diabetes Rat Model

Food Chemistry International, EarlyView.
This study evaluated Bambara groundnut–wheat composite bread fortified with orange peel in diabetic rats. Diets significantly lowered blood glucose, inhibited α‐glucosidase and α‐amylase, and boosted antioxidant enzymes compared to controls. Results emphasize BG‐based functional foods' potential to help manage type 2 diabetes through regulation of ...
S. O. Oguntuase, O. W. Fasakin, I. S. Oyeleye, G. Oboh   +3 more
wiley   +1 more source

Inhibitors of the renin-angiotensin system

, 1993
Inhibition of the renin-angiotensin system with angiotensin-converting enzyme inhibitors is well established as a treatment modality for hypertension and congestive heart failure.
Nussberger, J., Brunner, H. R., Waeber, B.   +2 more
core  

Infused Tiger Nut and Almond Nut Crunchy Snacks Enhanced the Nutritional Value and Antioxidant Activity in High‐Fat Diet Fed Rat

Food Chemistry International, EarlyView.
Crunches were produced from formulations of almond nuts and tiger nuts (AN–TN) for the plausible management of commodity disease of obese condition. The produced AN–TN crunches showed high consumers acceptability, phenolic, and amylopectin contents. In addition, formulated percentages of AN–TN crunches when fed to high‐fat diet (HFD) fed rats led to ...
Olufunke Florence Ajeigbe, Ayokunle Olubode Ademosun, Ganiyu Oboh, Oluwatobi Emmauel Allen, Bolaji Lawrence Awe   +4 more
wiley   +1 more source