Results 131 to 140 of about 3,459,561 (335)

Riligustilide Attenuated Renal Injury by the Blockade of Renin

Cellular Physiology and Biochemistry, 2018
Background/Aims: Nephropathy related with renin can be alleviated with ACE-inhibitors or AT1R blockers, whereas they might be ineffective after long-term administration because of a feedback production of enhanced renin.
Juan Kong, Li Han, Han Su, Yihan Hu, Xueshi Huang, Yan Lou   +5 more
doaj   +1 more source

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

Food Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima, István Dalmadi, Anna Jánosi, Krisztina Takács, Eszter Halmy   +4 more
wiley   +1 more source

The blockade of the renin-angiotensin system reverses tacrolimus related cardiovascular toxicity at the histopathological level

, 2007
Introduction. In this study, we investigate the toxic effects of tacrolimus (FK506) on the cardiovascular system at the histopathological level in a rat model and whether these effects can be reversed by the blockade of the renin-angiotensin system (RAS)
TUĞLULAR, ZÜBEYDE SERHAN
core   +1 more source

Prior Use of Renin-Angiotensin System Inhibitors and Risk of Renal Replacement Therapy in Critically Ill Elderly Patients With Sepsis: A Population-Based Cohort Study

Critical Care Explorations
OBJECTIVES:. We sought to estimate the association between chronic use of renin-angiotensin system inhibitors and acute kidney injury requiring renal replacement therapy in critically ill adult patients with sepsis. DESIGN:. Population-based cohort study
Victoria Otero Castro, MD, Damon C. Scales, MD, PhD, Federico Angriman, MD, MPH, PhD   +2 more
doaj   +1 more source

Mapping the Global Clinical Landscape of Pharmacological Therapies for Heart Failure With Preserved Ejection Fraction: An Analysis Based on ClinicalTrials.gov (2003–2025)

iMetaMed, EarlyView.
This study analyzed 236 heart failure with preserved ejection fraction (HFpEF) pharmacological trials registered on ClinicalTrials.gov from 2003 to 2025, revealing a post‐2016 surge (76.3%), U.S. dominance (58.5%), and prominence of SGLT2 inhibitors/novel therapies (each 13.1%).
Yucheng Hou, Jingwei Zhao, Yuqian Tang, Tan Liu, Zhiao Zhang, Ziheng Wang, Han Shen   +6 more
wiley   +1 more source

ACE‐inhibitory peptide Leu‐Tyr‐Ala in skeletal muscle actin exhibits anti‐aging effects through the inhibition of acn‐1 in Caenorhabditis elegans

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Inhibitors of angiotensin‐converting enzyme (ACE) are used in pharmaceuticals and functional foods. Captopril, a well‐known ACE inhibitor, extends the lifespan of the nematode Caenorhabditis elegans. Bioactive peptides derived from food sources are considered safe ACE inhibitors.
Issei Yokoyama, Minori Yamane, Kanaho Watanabe, Abdul Fatah, Yusuke Komiya, Jun Nagasao, Keizo Arihara   +6 more
wiley   +1 more source

Systematic review of the role of renin-angiotensin system inhibitors in late studies on Covid-19. A new challenge overcome?

, 2020
A role for the renin-angiotensin-aldosterone-system in Severe Acute Respiratory Syndrome-Coronavirus-2 infection and in the development of COronaVIrus Disease-19 disease has generated remarkable concerns among physicians and patients.
Battistoni, Allegra, Volpe, Massimo
core   +1 more source

Renin inhibitors are a new direction in the treatment of arterial hypertension

Терапевтический архив, 2010
The paper covers current problems in the treatment of arterial hypertension. Renin is an important and promising therapeutic target. The direct renin inhibitor aliskiren (Rasilez) is a promising current effective antihypertensive agent that has cardio ...
Yuriy Aleksandrovich Vasyuk, Irina Akhmedkhanovna Sadulaeva, Elena Nikolaevna Yushchuk, Ol'ga Sergeevna Trofimenko, Mikhail Vasil'evich Chirkov, Viktoriya Sergeevna Fedoseeva, Kirill Georgievich Kulikov, Yu A Vasyuk, I A Sadulayeva, E N Yushchuk, O S Trofimenko, M V Chirkov, V S Fedoseyeva, K G Kulikov   +13 more
doaj  

Experimental and Clinical Pharmacology: Renin inhibitors - mechanisms of action

, 2009
Renin inhibitors are antihypertensive drugs which block the first step in the renin ...
D. Campbell
semanticscholar   +1 more source

Atrial cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala, Monika Przewłocka‐Kosmala   +1 more
wiley   +1 more source