Results 91 to 100 of about 34,332 (263)
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
British Journal of Pharmacology, EarlyView.This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
Revista do Instituto de Medicina Tropical de São Paulo, 1984 Amostras de soros humanos coletadas nas cidades de Pelotas, Santiago e Uruguaiana, no Estado do Rio Grande do Sul, foram testadas para anticorpos inibidores da hemaglutinação contra reovírus.
Ivo Gomes de Mattos +2 more
doaj
Measles virus causes immunogenic cell death in human melanoma [PDF]
, 2011 Oncolytic viruses (OV) are promising treatments for cancer, with several currently undergoing testing in randomised clinical trials. Measles virus (MV) has not yet been tested in models of human melanoma.
Bond, Jacquelyn +14 more
core +1 more source
Cancer Science, EarlyView.OncoVV‑shHSP70, a vaccinia virus silencing HSP70, demonstrated potent antitumor efficacy in colorectal cancer cell lines, as well as in syngeneic, xenograft, and humanized mouse models. In cell lines, oncoVV‑shHSP70 promoted viral oncolysis and cytokine production through a self‑reinforcing cycle of ROS‑autophagy. In both CT26 and SW620‑humanized mouse
Rentao Yuan +8 more
wiley +1 more source
Journal of Clinical and Translational Science, 2018 OBJECTIVES/SPECIFIC AIMS: The overall goal is to determine if intestinal commensal bacteria play a role in enteric virus evolution. We will use reovirus, an enteric segmented virus, to investigate specific goals.
Matthew Lanahan +2 more
doaj +1 more source
The oncolytic efficacy and safety of avian reovirus and its dynamic distribution in infected mice
Experimental biology and medicine, 2019 Primary liver cancer is a major public health challenge that ranks as the third most common cause of cancer worldwide despite therapeutic improvement. Reovirus has been emerging as a potential anti-cancer agent and is undergoing multiple clinical trials,
R. Cai +7 more
semanticscholar +1 more source
Journal of Fish Diseases, Volume 48, Issue 4, April 2025.ABSTRACT Atlantic cod farming experiences renewed growth in Norway, and increased awareness is essential to address emerging diseases in this species. There are few reports on gill diseases in cod, and to date, no viral gill infections of cod have been documented. In this study, we collected samples from three sequential time points in summer 2023 from
Mona C. Gjessing +4 more
wiley +1 more source
Viruses, 2015 Viruses that specifically replicate in tumor over normal cells offer promising cancer therapies. Oncolytic viruses (OV) not only kill the tumor cells directly; they also promote anti-tumor immunotherapeutic responses.
Adil Mohamed +2 more
doaj +1 more source
Role of Myeloid Cells in Oncolytic Reovirus-Based Cancer Therapy
Viruses, 2021 Oncolytic reovirus preferentially targets and kills cancer cells via the process of oncolysis, and additionally drives clinically favorable antitumor T cell responses that form protective immunological memory against cancer relapse. This two-prong attack
Vishnupriyan Kumar +2 more
doaj +1 more source
Reovirus Receptors and Apoptosis
Virology, 2001 The mammalian reoviruses are a tractable experimental system for studies of viral replication and pathogenesis. Reovirus virions are nonenveloped, double-shelled particles containing a genome of 10 segments of doublestranded RNA (Nibert and Schiff, 2001).
Barton, Erik S. +4 more
openaire +2 more sources