Atomically precise metal cluster enzymes for pathological tissue regeneration
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong +11 more
wiley +1 more source
Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu +5 more
wiley +1 more source
In-vivo Antioxidant Effects of Emodin on Ischemia-Reperfusion Injury of Rat's Skeletal Muscle. [PDF]
Yiğit D +7 more
europepmc +1 more source
NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu +13 more
wiley +1 more source
In Vivo Extracellular Recording Reveals Bidirectional Changes in Neuronal Activity in the Rat Spinal Dorsal Horn After Hindlimb Ischemia-Reperfusion. [PDF]
Uta D +5 more
europepmc +1 more source
Association of Hospital Volume With Outcomes of Pulmonary Embolism in the United States
ABSTRACT Background Pulmonary embolism (PE) remains a leading cause of mortality in the United States. While prior studies show improved outcomes at higher‐volume centers, the understanding of procedural utilization remains limited. Aims Therefore, this study aimed to evaluate the association of hospital PE volume and intervention utilization with ...
Zihan Gao +5 more
wiley +1 more source
Cardioprotective Effect of Aloin Against Ischemia/Reperfusion Injury: Experimental and Computational POM Approaches. [PDF]
Kadi M +12 more
europepmc +1 more source
ABSTRACT A 34‐year‐old man with no cardiovascular history presented with anterior ST‐elevation myocardial infarction and a large thrombotic occlusion of the mid left anterior descending artery. Following potent antithrombotic therapy and mechanical thrombus aspiration, angiography revealed vessel patency without residual significant stenosis, allowing ...
Domenico Simone Castiello +3 more
wiley +1 more source
Intravenous Atropine in Reducing Reperfusion Arrhythmias, Conduction Abnormalities, and Hypotension in Inferior ST-elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. [PDF]
Rashed MI +3 more
europepmc +1 more source

