Results 11 to 20 of about 432,839 (343)
Targeting Oxidative Stress and Inflammation to Prevent Ischemia-Reperfusion Injury
Frontiers in Molecular Neuroscience, 2020 The cerebral ischemia injury can result in neuronal death and/or functional impairment, which leads to further damage and dysfunction after recovery of blood supply.
Liquan Wu +6 more
semanticscholar +1 more source
PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons
Neural Regeneration Research, 2022 PANoptosis is a newly identified type of regulated cell death that consists of pyroptosis, apoptosis, and necroptosis, which simultaneously occur during the pathophysiological process of infectious and inflammatory diseases.
Weitao Yan +7 more
semanticscholar +1 more source
Postconditioning: Reperfusion of “reperfusion injury” after hibernation [PDF]
Cardiovascular Research, 2006 The newly developed concept of postconditioning as a way of reducing reperfusion injury has been receiving much attention in the literature, both in basic science and clinical circles. Cardiovascular Research will be hosting a Spotlight Issue entitled “ Cardiac Protection by Pre- and Postconditioning ” in May of this year.
David, Garcia-Dorado +1 more
openaire +2 more sources
Free Radical Biology and Medicine, 1988 Several lines of evidence point to a major role of oxygen free radicals in the pathogenesis of cell death or dysfunction in a variety of disease processes. Recent studies from this as well as other laboratories have demonstrated that oxygen free radicals play a major role in the pathogenesis of post-ischemic reperfusion injury in the heart.
J T, Flaherty, M L, Weisfeldt
+5 more sources
Biomedicines, 2021 Hepatocellular carcinoma has become a leading cause of cancer-associated mortality throughout the world, and is of great concern. Currently used chemotherapeutic drugs in the treatment of hepatocellular carcinoma lead to severe side effects, thus ...
Ana I. Álvarez-Mercado +8 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Baicalin is a natural flavonoid glycoside that confers protection against myocardial ischemia/reperfusion (I/R) injury. However, its mechanism has not been fully understood.
Zhenyu Fan +4 more
semanticscholar +1 more source
BMC Cardiovascular Disorders, 2020 Background Left ventricular remodeling following ST-elevation myocardial infarction (STEMI) is associated with poor outcome, including heart failure (HF).
Damien Legallois +8 more
doaj +1 more source
Frontiers in Immunology, 2021 The resolution of the acute inflammatory response is governed by phagocytes actively clearing apoptotic cells and pathogens. Biosynthesis of the specialized pro-resolving mediators (SPMs) is pivotal in the resolution of inflammation via their roles in ...
Stephania Libreros +6 more
doaj +1 more source
Cerebral Edema in Patients with severe Hemispheric Syndrome: Incidence, Risk Factors, and Outcomes—Data from SITS-ISTR [PDF]
Journal of Stroke, 2023 Background and Purpose Cerebral edema (CED) in ischemic stroke can worsen prognosis and about 70% of patients who develop severe CED die if treated conservatively.
Irene Escudero-Martínez +11 more
doaj +1 more source
Targeting Ferroptosis: Pathological Mechanism and Treatment of Ischemia-Reperfusion Injury
Oxidative Medicine and Cellular Longevity, 2021 Ischemia-reperfusion (I/R) is a pathological process that occurs in many organs and diseases. Reperfusion, recovery of blood flow, and reoxygenation often lead to reperfusion injury. Drug therapy and early reperfusion therapy can reduce tissue injury and
Xinye Li +11 more
semanticscholar +1 more source