Results 11 to 20 of about 382,913 (294)

Ischemia/reperfusion-activated ferroptosis in the early stage triggers excessive inflammation to aggregate lung injury in rats

open access: yesFrontiers in Medicine, 2023
ObjectiveLung ischemia/reperfusion injury (LIRI) is a clinical syndrome of acute lung injury that occurs after lung transplantation or remote organ ischemia.
Xiujie Liu   +15 more
doaj   +1 more source

TRPM4 Participates in Aldosterone-Salt-Induced Electrical Atrial Remodeling in Mice

open access: yesCells, 2021
Aldosterone plays a major role in atrial structural and electrical remodeling, in particular through Ca2+-transient perturbations and shortening of the action potential.
Christophe Simard   +6 more
doaj   +1 more source

Kinetic and mechanistic diversity of intestinal immune homeostasis characterized by rapid removal of gut bacteria

open access: yesGut Microbes, 2023
Symbiotic microbiota critically contribute to host immune homeostasis in effector cell-specific manner. For exclusion of microbial component, germ-free animals have been the gold standard method.
Da-Jung Jung   +6 more
doaj   +1 more source

Early activation and recruitment of invariant natural killer T cells during liver ischemia-reperfusion: the major role of the alarmin interleukin-33

open access: yesFrontiers in Immunology, 2023
Over the past thirty years, the complexity of the αβ-T cell compartment has been enriched by the identification of innate-like T cells (ITCs), which are composed mainly of invariant natural killer T (iNKT) cells and mucosal-associated invariant T (MAIT ...
Aurélie Robin   +11 more
doaj   +1 more source

Unconventional immune cells in the gut mucosal barrier: regulation by symbiotic microbiota

open access: yesExperimental and Molecular Medicine, 2023
The mammalian gut is the most densely colonized organ by microbial species, which are in constant contact with the host throughout life. Hosts have developed multifaceted cellular and molecular mechanisms to distinguish and respond to benign and ...
Ji-Sun Yoo, Sungwhan F. Oh
doaj   +1 more source

Postconditioning: Reperfusion of “reperfusion injury” after hibernation [PDF]

open access: yesCardiovascular Research, 2006
The newly developed concept of postconditioning as a way of reducing reperfusion injury has been receiving much attention in the literature, both in basic science and clinical circles. Cardiovascular Research will be hosting a Spotlight Issue entitled “ Cardiac Protection by Pre- and Postconditioning ” in May of this year.
David, Garcia-Dorado   +1 more
openaire   +2 more sources

Reperfusion injury

open access: yesFree Radical Biology and Medicine, 1988
Several lines of evidence point to a major role of oxygen free radicals in the pathogenesis of cell death or dysfunction in a variety of disease processes. Recent studies from this as well as other laboratories have demonstrated that oxygen free radicals play a major role in the pathogenesis of post-ischemic reperfusion injury in the heart.
J T, Flaherty, M L, Weisfeldt
  +5 more sources

Serum neprilysin levels are associated with myocardial stunning after ST-elevation myocardial infarction

open access: yesBMC Cardiovascular Disorders, 2020
Background Left ventricular remodeling following ST-elevation myocardial infarction (STEMI) is associated with poor outcome, including heart failure (HF).
Damien Legallois   +8 more
doaj   +1 more source

A New E-Series Resolvin: RvE4 Stereochemistry and Function in Efferocytosis of Inflammation-Resolution

open access: yesFrontiers in Immunology, 2021
The resolution of the acute inflammatory response is governed by phagocytes actively clearing apoptotic cells and pathogens. Biosynthesis of the specialized pro-resolving mediators (SPMs) is pivotal in the resolution of inflammation via their roles in ...
Stephania Libreros   +6 more
doaj   +1 more source

Insights into Growth Factors in Liver Carcinogenesis and Regeneration: An Ongoing Debate on Minimizing Cancer Recurrence after Liver Resection

open access: yesBiomedicines, 2021
Hepatocellular carcinoma has become a leading cause of cancer-associated mortality throughout the world, and is of great concern. Currently used chemotherapeutic drugs in the treatment of hepatocellular carcinoma lead to severe side effects, thus ...
Ana I. Álvarez-Mercado   +8 more
doaj   +1 more source

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