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Ischemia-reperfusion syndrome

Khirurgiya. Zhurnal im. N.I. Pirogova, 2021
The ischemia-reperfusion syndrome complicates the course of a number of emergency conditions in various fields of clinical medicine, determines the course, prognosis and outcome of the disease. This review examines various aspects of the etiology, pathogenesis, and clinical manifestations of this syndrome. Particular attention is paid to its prevention
openaire   +2 more sources

Myocardial Reperfusion Injury

New England Journal of Medicine, 2007
Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration of coronary blood flow after an ischemic episode. This review focuses on the mechanisms of the injury, on attempts to protect the heart against it, and on promising new approaches to cardioprotection during percutaneous coronary intervention.
Derek M, Yellon, Derek J, Hausenloy
openaire   +5 more sources

Reperfusion therapy

Emergency Nurse, 2006
In this article Nick Castle explains that, with significant improvements being made to the emergency management of cardiac patients, emergency nurses should challenge and develop their clinical practice to ensure patients receive prompt and evidence based treatment.
openaire   +2 more sources

Pulmonary Reperfusion Syndrome

The Annals of Thoracic Surgery, 1979
"Reperfusion syndrome" of the lung may play a role in the pulmonary edema and hemorrhage that occur following pulmonary embolectomy, cardiopulmonary bypass, and shock. Bioenergetic, metabolic, and ultrastructural studies of canine lungs indicate that ventilated lung tissue could tolerate 5 hours of pulmonary arterial occlusion with minimal damage ...
D L, Modry, R C, Chiu
openaire   +2 more sources

Controlled Reperfusion Against Ischemia Reperfusion Injury

2018
Recanalization and reperfusion after an ischemic stroke sometimes could be harmful and deadly, and controlled perfusion may be a potential solution. This article summarized controlled perfusion literature, both animal and clinical, on heart, lung, kidney, and limbs and compared with brain controlled perfusion.
Weijian Jiang   +3 more
openaire   +1 more source

Myocardial Reperfusion Injury

Critical Care Nursing Clinics of North America, 1990
A review of the mechanism of ischemic-reperfusion injury, proposed interventions to prevent injury, and future directions have been presented to enhance the practitioner's knowledge of this new, exciting concept in myocardial injury. There is increasing evidence in the literature that reperfusion injury may occur in other organ systems and is ...
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Beyond Epicardial Reperfusion

New England Journal of Medicine, 2007
The pathogenesis of an acute myocardial infarction consists of the rupture of atherosclerotic plaque, followed by a sudden thrombotic coronary occlusion.
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Controlled perfusion decreases reperfusion injury after high-flow reperfusion

The Journal of Heart and Lung Transplantation, 2002
Some investigators have suggested that high pulmonary artery flow rates increase the risk of severe reperfusion injury after lung transplantation. We hypothesized that controlling the initial flow rate and pulmonary artery pressure would decrease the severity of lung dysfunction in the setting of high-flow reperfusion.Using our isolated, ventilated ...
Steven M, Fiser   +7 more
openaire   +2 more sources

Hyperoxia during reperfusion is a factor in reperfusion injury

Free Radical Biology and Medicine, 1989
Imposition of ischemia should result in accumulation of lactic acid with an attendant drop in pH. Subsequent reperfusion would result in hyperoxia, in the affected tissue, due to the Bohr Effect. O2- should therefore be produced in greater than normal amounts, due to this transient hyperoxia, and may contribute to reperfusion injury.
M L, Wolbarsht, I, Fridovich
openaire   +2 more sources

Early Reperfusion Phenomena

Seminars in Cardiothoracic and Vascular Anesthesia, 2006
Cycles of ischemia-reperfusion are ubiquitous in clinical cardiology. Depending on the duration and intensity of the ischemic episode as well as its repetition mode, several pathophysiologic syndromes have been identified, such as myocardial stunning, hibernation, and preconditioning.
openaire   +2 more sources

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