Results 21 to 30 of about 432,839 (343)
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
Nature, 2014 Ischaemia-reperfusion injury occurs when the blood supply to an organ is disrupted and then restored, and underlies many disorders, notably heart attack and stroke.
Edward T. Chouchani +28 more
semanticscholar +1 more source
Turkish Journal of Vascular Surgery, 2023 Aim: Lower limb ischemia/reperfusion leads to distant organ dysfunction, notably affecting the lungs, resulting in respiratory failure and significant morbidity and mortality.
Mehmet Ceber +4 more
doaj +1 more source
Current Mechanistic Concepts in Ischemia and Reperfusion Injury
Cellular Physiology and Biochemistry, 2018 Ischemia-reperfusion injury is associated with serious clinical manifestations, including myocardial hibernation, acute heart failure, cerebral dysfunction, gastrointestinal dysfunction, systemic inflammatory response syndrome, and multiple organ ...
Meng-Yu Wu +7 more
semanticscholar +1 more source
Science Advances, 2020 Nanotherapeutics reverses reperfusion-induced injury in ischemic stroke. Rational design of potent antioxidative agent with high biocompatibility is urgently needed to treat ischemic reperfusion-induced ROS-mediated cerebrovascular and neural injury ...
Lizhen He +5 more
semanticscholar +1 more source
Cell Death and Differentiation, 2019 Ferroptosis is a recently identified form of regulated cell death defined by the iron-dependent accumulation of lipid reactive oxygen species. Ferroptosis has been studied in various diseases such as cancer, Parkinson’s disease, and stroke.
Yang Li +10 more
semanticscholar +1 more source
Mediator-lipidomics: databases and search algorithms for PUFA-derived mediators
Journal of Lipid Research, 2005 Lipid mediators (LMs) derived from PUFAs play important roles in health and disease. Databases and search algorithms are crucial, but currently unavailable, for accurate and prompt analysis of LMs via liquid chromatography-ultraviolet-tandem mass ...
Yan Lu +3 more
doaj +1 more source
Target temperature management in traumatic brain injury with a focus on adverse events, recognition, and prevention [PDF]
Acute and Critical Care, 2022 Traumatic brain injury (TBI) is a critical cause of disability and death worldwide. Many studies have been conducted aimed at achieving favorable neurologic outcomes by reducing secondary brain injury in TBI patients.
Kwang Wook Jo
doaj +1 more source
The Scientific World Journal, 2002 Inflammatory diseases of mucosal organs as diverse as the lung, kidney, and intestine, inevitably require the intimate interactions of neutrophils with columnar epithelia.
Sean P. Colgan +2 more
doaj +1 more source
Marital status and long-term cardiovascular risk in general population (Gubbio, Italy)
Scientific Reports, 2023 To investigate whether marital status is associated to long-term major fatal and non-fatal cardiovascular events in men and women from the Gubbio Population Study. The incidence of cardiovascular disease (CVD), including stroke and coronary heart disease
Xavier Humbert +8 more
doaj +1 more source
Receptor mechanism of infarct-limiting effect of adaptation to normobaric hypoxia
Бюллетень сибирской медицины, 2021 The aim of the study was to investigate the involvement of bradykinin, cannabinoid and vanilloid (TRPV1 channel) receptors in the implementation of the infarct-limiting effect of chronic normobaric hypoxia (CNH).Materials and methods.
N. V. Naryzhnaya +3 more
doaj +1 more source