Results 1 to 10 of about 2,272,622 (291)
Lipid Mediator Informatics and Proteomics in Inflammation-Resolution
The Scientific World Journal, 2006 Lipid mediator informatics is an emerging area denoted to the identification of bioactive lipid mediators (LMs) and their biosynthetic profiles and pathways.
Yan Lu +3 more
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Ischemia-reperfusion injury: molecular mechanisms and therapeutic targets
Signal Transduction and Targeted TherapyIschemia-reperfusion (I/R) injury paradoxically occurs during reperfusion following ischemia, exacerbating the initial tissue damage. The limited understanding of the intricate mechanisms underlying I/R injury hinders the development of effective ...
Meng Zhang +9 more
semanticscholar +1 more source
The Scientific World Journal, 2002 It is well appreciated that lipid-derived mediators play key roles in inflammation and many other physiologic responses where multicellular processes are involved.
Charles N. Serhan, Nan Chiang
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Clinical Cardiology, 1990 AbstractThis article reviews the early and late morphologic changes associated with reperfusion of ischemic myocardium. If instituted within minutes of coronary artery occlusion, all reversibly injured myocardium is salvaged. Once some irreversibly injured myocardium is present, the usually bland region of coagulation necrosis is transformed into an ...
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Postconditioning: Reperfusion of “reperfusion injury” after hibernation [PDF]
Cardiovascular Research, 2006 The newly developed concept of postconditioning as a way of reducing reperfusion injury has been receiving much attention in the literature, both in basic science and clinical circles. Cardiovascular Research will be hosting a Spotlight Issue entitled “ Cardiac Protection by Pre- and Postconditioning ” in May of this year.
David, Garcia-Dorado +1 more
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MicroRNA-670 aggravates cerebral ischemia/reperfusion injury via the Yap pathway
Neural Regeneration Research, 2021 Apoptosis is an important programmed cell death process involved in ischemia/reperfusion injury. MicroRNAs are considered to play an important role in the molecular mechanism underlying the regulation of cerebral ischemia and reperfusion injury. However,
Shi-Jia Yu +4 more
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Global MicroRNA Expression Profiling of Mouse Livers following Ischemia-Reperfusion Injury at Different Stages. [PDF]
PLoS ONE, 2016 Hepatic ischemia-reperfusion injury is a dynamic process consisting of two stages: ischemia and reperfusion, and triggers a cascade of physiological and biochemical events.
Weisheng Zheng +11 more
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Biology Open, 2017 The removal of mRNA transcript poly(A) tails by 3′→5′ exonucleases is the rate-limiting step in mRNA decay in eukaryotes. Known cellular deadenylases are the CCR4-NOT and PAN complexes, and poly(A)-specific ribonuclease (PARN).
Taylor E. Miller +1 more
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Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats [PDF]
Acta Cirúrgica Brasileira, 2017 Purpose: To investigate the effects of cyclosporine A on renal ischemia-reperfusion injury during transient hyperglycemia in rats. Methods: In a model of ischemia-reperfusion-induced renal injury and transiently induced hyperglycemia by intraperitoneal
Sylvio Valença de Lemos Neto +9 more
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Low-dose pro-resolving mediators temporally reset the resolution response to microbial inflammation
Molecular MedicineBackground Specialized pro-resolving mediators (SPMs) promote resolution of inflammation, clear infections and stimulate tissue regeneration. These include resolvins, protectins, and maresins.
Charles N. Serhan +2 more
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