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Ischemia and reperfusion injury in kidney transplantation : relevant mechanisms in injury and repair [PDF]
Journal of Clinical Medicine, 2020 Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation.
Berger, Stefan P. +7 more
core +3 more sources
PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons
Neural Regeneration Research, 2023 PANoptosis is a newly identified type of regulated cell death that consists of pyroptosis, apoptosis, and necroptosis, which simultaneously occur during the pathophysiological process of infectious and inflammatory diseases.
Wei-Tao Yan +7 more
doaj +2 more sources
Current Mechanistic Concepts in Ischemia and Reperfusion Injury
Cellular Physiology and Biochemistry, 2018 Ischemia-reperfusion injury is associated with serious clinical manifestations, including myocardial hibernation, acute heart failure, cerebral dysfunction, gastrointestinal dysfunction, systemic inflammatory response syndrome, and multiple organ ...
Meng-Yu Wu +7 more
doaj +2 more sources
Frontiers in Medicine, 2023 ObjectiveLung ischemia/reperfusion injury (LIRI) is a clinical syndrome of acute lung injury that occurs after lung transplantation or remote organ ischemia.
Xiujie Liu +15 more
doaj +1 more source
Circulation, 2023 Background: Myocardial ischemia-reperfusion (I/R) injury causes cardiac dysfunction to myocardial cell loss and fibrosis. Prevention of cell death is important to protect cardiac function after I/R injury.
Wenbin Cai +9 more
semanticscholar +1 more source
Gut Microbes, 2023 Symbiotic microbiota critically contribute to host immune homeostasis in effector cell-specific manner. For exclusion of microbial component, germ-free animals have been the gold standard method.
Da-Jung Jung +6 more
doaj +1 more source
Frontiers in Immunology, 2022 Liver transplantation is the ultimate method for treating end-stage liver disease. With the increasing prevalence of obesity, the number of patients with non-alcoholic fatty liver, a common cause of chronic liver disease, is on the rise and may become ...
S. Tang +5 more
semanticscholar +1 more source
Unconventional immune cells in the gut mucosal barrier: regulation by symbiotic microbiota
Experimental and Molecular Medicine, 2023 The mammalian gut is the most densely colonized organ by microbial species, which are in constant contact with the host throughout life. Hosts have developed multifaceted cellular and molecular mechanisms to distinguish and respond to benign and ...
Ji-Sun Yoo, Sungwhan F. Oh
doaj +1 more source
Targeting Ferroptosis: Pathological Mechanism and Treatment of Ischemia-Reperfusion Injury
Oxidative Medicine and Cellular Longevity, 2021 Ischemia-reperfusion (I/R) is a pathological process that occurs in many organs and diseases. Reperfusion, recovery of blood flow, and reoxygenation often lead to reperfusion injury. Drug therapy and early reperfusion therapy can reduce tissue injury and
Xinye Li +11 more
semanticscholar +1 more source
Biomedicines, 2021 Hepatocellular carcinoma has become a leading cause of cancer-associated mortality throughout the world, and is of great concern. Currently used chemotherapeutic drugs in the treatment of hepatocellular carcinoma lead to severe side effects, thus ...
Ana I. Álvarez-Mercado +8 more
doaj +1 more source