Results 171 to 180 of about 199,564 (290)

Myo‐Inositol Mitigates Oxidative Stress in Bovine Mammary Epithelial Cells via Activation of the SIRT5/Nrf2 Signaling Axis

Animal Research and One Health, EarlyView.
Myo‐inositol alleviates oxidative stress in dairy cow mammary epithelial cells via the Sirt5/Nrf2 pathway to promote mitochondrial fusion. This graphical abstract was created with BioRender.com. ABSTRACT High‐yielding dairy cows are susceptible to mammary gland oxidative stress due to prolonged intensive lactation, leading to redox imbalance.
Yufei Zhang, Yu Cao, Meng Zhang, Huijie Hu, He Ma, Junlong Bi, Juxiong Liu, Shoupeng Fu, Wenjin Guo   +8 more
wiley   +1 more source

Organ-protective effects of fullerenol and desflurane in a rat model of ischemia-reperfusion injury. [PDF]

Sci Rep
Kip G, Köksal Z, Yığman Z, Küçük A, Arslan M, Akarca Dizakar SÖ, Güneş I, Dursun AD, Şıvgın V.   +8 more
europepmc   +1 more source

Lateral intracerebroventricular injection of Apelin-13 inhibits apoptosis after cerebral ischemia/reperfusion injury

, 2015
Bo Bai, Xiao-ge Yan, Baohua Cheng, Xin Wang, Liangcai Ding, Haiqing Liu, Jing Chen   +6 more
openalex   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

A Multifunctional Nanoplatform for Treating Hepatic Ischemia-Reperfusion Injury by Modulating the Nrf2 and NF-κB Pathways. [PDF]

ACS Appl Mater Interfaces
Shuai L, Wang X, Wen X, Peng C, Dong T, Lai J, Yao L, Fan S, Zhao C, Zhang L, Zhang Y, Xiong X.   +11 more
europepmc   +1 more source

Cytokine pathways driving diverse tissue pathologies in rheumatoid arthritis

Arthritis &Rheumatology, Accepted Article.
Rheumatoid arthritis is a complex systemic disorder characterised primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease e.g. of the lung with potentially devastating clinical consequences.
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Ischaemia-Reperfusion Injury in Organ Transplantation: Role of Coenzyme Q10. [PDF]

J Clin Med
Mantle D, Cufflin N, Purcell TT, Hargreaves IP.   +3 more
europepmc   +1 more source

Bufalin Ameliorates Myocardial Ischemia/Reperfusion Injury by Suppressing Macrophage Pyroptosis via P62 Pathway [PDF]

Chang Li, Zhen Ma, Xiang Wei, Ying Wang, Jian Wu, Xuan Li, Xiaolei Sun, Zhiwen Ding, Cheng Yang, Yunzeng Zou   +9 more
openalex   +1 more source

A cooperative release of mitochondrial DNA from platelets and neutrophils drives an interferon signature in systemic sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis, André N. Tiaden, Simone Häner‐Massimi, Diego Kyburz, Cedric André, Anton Glück, Enrico Ferrero, Stuart Hawtin, Tobias Junt, Ulrich A. Walker   +9 more
wiley   +1 more source

USP43 promotes cerebral ischemia-reperfusion injury via activation of TAK1. [PDF]

Cell Biosci
Dong Y, Hu S, Zhang R, Zhang T, Feng Y, Sun W, Zhang P, Chen J, Zhao W.   +8 more
europepmc   +1 more source