Results 11 to 20 of about 2,272,622 (291)

Current Mechanistic Concepts in Ischemia and Reperfusion Injury

open access: yesCellular Physiology and Biochemistry, 2018
Ischemia-reperfusion injury is associated with serious clinical manifestations, including myocardial hibernation, acute heart failure, cerebral dysfunction, gastrointestinal dysfunction, systemic inflammatory response syndrome, and multiple organ ...
Meng-Yu Wu   +7 more
doaj   +2 more sources

Ischemia/reperfusion-activated ferroptosis in the early stage triggers excessive inflammation to aggregate lung injury in rats

open access: yesFrontiers in Medicine, 2023
ObjectiveLung ischemia/reperfusion injury (LIRI) is a clinical syndrome of acute lung injury that occurs after lung transplantation or remote organ ischemia.
Xiujie Liu   +15 more
doaj   +1 more source

Alox15/15-HpETE Aggravates Myocardial Ischemia-Reperfusion Injury by Promoting Cardiomyocyte Ferroptosis

open access: yesCirculation, 2023
Background: Myocardial ischemia-reperfusion (I/R) injury causes cardiac dysfunction to myocardial cell loss and fibrosis. Prevention of cell death is important to protect cardiac function after I/R injury.
Wenbin Cai   +9 more
semanticscholar   +1 more source

Kinetic and mechanistic diversity of intestinal immune homeostasis characterized by rapid removal of gut bacteria

open access: yesGut Microbes, 2023
Symbiotic microbiota critically contribute to host immune homeostasis in effector cell-specific manner. For exclusion of microbial component, germ-free animals have been the gold standard method.
Da-Jung Jung   +6 more
doaj   +1 more source

Abnormalities of glucose and lipid metabolism in myocardial ischemia-reperfusion injury.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023
Myocardial ischemia-reperfusion injury is a common condition in cardiovascular diseases, and the mechanism of its occurrence involves multiple complex metabolic pathways and signaling pathways.
Hao Tian   +3 more
semanticscholar   +1 more source

Reperfusion injury

open access: yesFree Radical Biology and Medicine, 1988
Several lines of evidence point to a major role of oxygen free radicals in the pathogenesis of cell death or dysfunction in a variety of disease processes. Recent studies from this as well as other laboratories have demonstrated that oxygen free radicals play a major role in the pathogenesis of post-ischemic reperfusion injury in the heart.
J T, Flaherty, M L, Weisfeldt
  +5 more sources

Mechanistic Insight and Clinical Implications of Ischemia/Reperfusion Injury Post Liver Transplantation

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2023
Ischemia/reperfusion injury is an inevitable process during liver transplantation and can lead to a high incidence of early allograft dysfunction and graft failure.
Jiang Liu, Kwan Man
semanticscholar   +1 more source

Myocardial Reperfusion Injury

open access: yesNew England Journal of Medicine, 2007
Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration of coronary blood flow after an ischemic episode. This review focuses on the mechanisms of the injury, on attempts to protect the heart against it, and on promising new approaches to cardioprotection during percutaneous coronary intervention.
Derek M, Yellon, Derek J, Hausenloy
  +11 more sources

Unconventional immune cells in the gut mucosal barrier: regulation by symbiotic microbiota

open access: yesExperimental and Molecular Medicine, 2023
The mammalian gut is the most densely colonized organ by microbial species, which are in constant contact with the host throughout life. Hosts have developed multifaceted cellular and molecular mechanisms to distinguish and respond to benign and ...
Ji-Sun Yoo, Sungwhan F. Oh
doaj   +1 more source

Myocardial ischemia/reperfusion injury: Mechanisms of injury and implications for management (Review)

open access: yesExperimental and Therapeutic Medicine, 2022
Myocardial infarction is one of the primary causes of mortality in patients with coronary heart disease worldwide. Early treatment of acute myocardial infarction restores blood supply of ischemic myocardium and decreases the mortality risk. However, when
Jianfeng He   +6 more
semanticscholar   +1 more source

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