Results 11 to 20 of about 2,176,828 (392)

Baicalin Prevents Myocardial Ischemia/Reperfusion Injury Through Inhibiting ACSL4 Mediated Ferroptosis

open access: yesFrontiers in Pharmacology, 2021
Baicalin is a natural flavonoid glycoside that confers protection against myocardial ischemia/reperfusion (I/R) injury. However, its mechanism has not been fully understood.
Zhenyu Fan   +4 more
semanticscholar   +1 more source

A New E-Series Resolvin: RvE4 Stereochemistry and Function in Efferocytosis of Inflammation-Resolution

open access: yesFrontiers in Immunology, 2021
The resolution of the acute inflammatory response is governed by phagocytes actively clearing apoptotic cells and pathogens. Biosynthesis of the specialized pro-resolving mediators (SPMs) is pivotal in the resolution of inflammation via their roles in ...
Stephania Libreros   +6 more
doaj   +1 more source

Myocardial Ischemia-Reperfusion Injury: Therapeutics from a Mitochondria-Centric Perspective

open access: yesThe Cardiology, 2021
Coronary arterial disease is the most common cardiovascular disease. Myocardial ischemia-reperfusion injury caused by the initial interruption of organ blood flow and subsequent restoration of organ blood flow is an important clinical problem with ...
Manli Zhou   +7 more
semanticscholar   +1 more source

Targeting Oxidative Stress and Inflammation to Prevent Ischemia-Reperfusion Injury

open access: yesFrontiers in Molecular Neuroscience, 2020
The cerebral ischemia injury can result in neuronal death and/or functional impairment, which leads to further damage and dysfunction after recovery of blood supply.
Liquan Wu   +6 more
semanticscholar   +1 more source

Ischaemia-reperfusion injury [PDF]

open access: yesJournal of Vascular Surgery, 2000
Journal of Vascular Surgery 31 (2000) 1081-1082. doi:10.1067/mva.2000.105513 ; Received by publisher: 0000-01-01 ; Harvest Date: 2016-01-04 12:22:44 ; DOI:10.1067/mva.2000.105513 ; Page Range: 1081 ...
University of Florida, College of Medicine, Gainesville, Fla ( host institution )   +1 more
openaire   +3 more sources

Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]

open access: yes, 2002
Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Baron, A.   +5 more
core   +1 more source

The protective effect of M40401, a superoxide dismutase mimetic, on post-ischemic brain damage in Mongolian gerbils [PDF]

open access: yes, 2003
BACKGROUND: Overproduction of free radical species has been shown to occur in brain tissues after ischemia-reperfusion injury. However, most of free radical scavengers known to antagonize oxidative damage (e.g. superoxide dismutase, catalase), are unable
Granato, Teresa   +8 more
core   +2 more sources

Myocardial reperfusion injury [PDF]

open access: yesEuropean Heart Journal Supplements, 2002
Post-ischaemic reperfusion carries an injurious component that may partly counteract the beneficial effects of reflow; this component has been termed ‘reperfusion injury’. Principal mediators of this phenomenon are oxygen radicals and neutrophils. Oxygen radicals, generated in large amounts upon reflow, induce oxidative tissue damage and modulate ...
AMBROSIO, Giuseppe, TRITTO, Isabella
openaire   +2 more sources

Role of autophagy in hypoxia-reoxygenation-induced injury of rat alveolar epithelial cell type Ⅱ [PDF]

open access: yesJichu yixue yu linchuang, 2021
Objective To investigate the role of autophagy in the hypoxia-reoxygenation (H/R) model of rat alveolar epithelial cell type Ⅱ (AEC Ⅱ). Methods Cells were randomly divided into control group (C),hypoxia-reoxygenation group (H/R),solvent group
LIU Xiu-jie, WANG Xin-yun, SONG Zheng-yang, LOU Guo-qiang, HAO Mao-lin, QIAN Wei, WANG Wan-tie
doaj  

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

open access: yesNature, 2014
Ischaemia-reperfusion injury occurs when the blood supply to an organ is disrupted and then restored, and underlies many disorders, notably heart attack and stroke.
Edward T. Chouchani   +28 more
semanticscholar   +1 more source

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