Results 21 to 30 of about 2,272,622 (291)
Frontiers in Immunology, 2022 Liver transplantation is the ultimate method for treating end-stage liver disease. With the increasing prevalence of obesity, the number of patients with non-alcoholic fatty liver, a common cause of chronic liver disease, is on the rise and may become ...
S. Tang +5 more
semanticscholar +1 more source
Frontiers in Immunology, 2021 The resolution of the acute inflammatory response is governed by phagocytes actively clearing apoptotic cells and pathogens. Biosynthesis of the specialized pro-resolving mediators (SPMs) is pivotal in the resolution of inflammation via their roles in ...
Stephania Libreros +6 more
doaj +1 more source
PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons
Neural Regeneration Research, 2022 PANoptosis is a newly identified type of regulated cell death that consists of pyroptosis, apoptosis, and necroptosis, which simultaneously occur during the pathophysiological process of infectious and inflammatory diseases.
Weitao Yan +7 more
semanticscholar +1 more source
Biomedicines, 2021 Hepatocellular carcinoma has become a leading cause of cancer-associated mortality throughout the world, and is of great concern. Currently used chemotherapeutic drugs in the treatment of hepatocellular carcinoma lead to severe side effects, thus ...
Ana I. Álvarez-Mercado +8 more
doaj +1 more source
Targeting Ferroptosis: Pathological Mechanism and Treatment of Ischemia-Reperfusion Injury
Oxidative Medicine and Cellular Longevity, 2021 Ischemia-reperfusion (I/R) is a pathological process that occurs in many organs and diseases. Reperfusion, recovery of blood flow, and reoxygenation often lead to reperfusion injury. Drug therapy and early reperfusion therapy can reduce tissue injury and
Xinye Li +11 more
semanticscholar +1 more source
Frontiers in Pharmacology, 2021 Baicalin is a natural flavonoid glycoside that confers protection against myocardial ischemia/reperfusion (I/R) injury. However, its mechanism has not been fully understood.
Zhenyu Fan +4 more
semanticscholar +1 more source
Myocardial Ischemia-Reperfusion Injury: Therapeutics from a Mitochondria-Centric Perspective
The Cardiology, 2021 Coronary arterial disease is the most common cardiovascular disease. Myocardial ischemia-reperfusion injury caused by the initial interruption of organ blood flow and subsequent restoration of organ blood flow is an important clinical problem with ...
Manli Zhou +7 more
semanticscholar +1 more source
Cell Metabolism, 2021 Myocardial ischemia-reperfusion (MIR) injury is a major cause of adverse outcomes of revascularization after myocardial infarction. To identify the fundamental regulator of reperfusion injury, we performed metabolomics profiling in plasma of individuals ...
Xiao-Jing Zhang +33 more
semanticscholar +1 more source
Phytomedicine, 2022 BACKGROUND Mitophagy plays a critical role in cerebral ischemia/reperfusion by timely removal of dysfunctional mitochondria. In mammals, PINK1/Parkin is the most classic pathway mediating mitophagy.
Zhiguo Mao +7 more
semanticscholar +1 more source
Targeting Oxidative Stress and Inflammation to Prevent Ischemia-Reperfusion Injury
Frontiers in Molecular Neuroscience, 2020 The cerebral ischemia injury can result in neuronal death and/or functional impairment, which leads to further damage and dysfunction after recovery of blood supply.
Liquan Wu +6 more
semanticscholar +1 more source