Results 31 to 40 of about 2,176,828 (392)
Frontiers in Cardiovascular Medicine, 2021 Myocardial ischemia/reperfusion injury is a common clinical problem and can result in severe cardiac dysfunction. Previous studies have demonstrated the protection of electroacupuncture against myocardial ischemia/reperfusion injury. However, the role of
Nisha Wang +9 more
doaj +1 more source
Inhibition of NAADP signalling on reperfusion protects the heart by preventing lethal calcium oscillations via two-pore channel 1 and opening of the mitochondrial permeability transition pore [PDF]
, 2015 Aims In the heart, a period of ischaemia followed by reperfusion evokes powerful cytosolic Ca2+ oscillations that can cause lethal cell injury. These signals represent attractive cardioprotective targets, but the underlying mechanisms of genesis are ill ...
A. Ganesan +13 more
core +1 more source
The pathological role of ferroptosis in ischemia/reperfusion-related injury
Zoological Research, 2020 Ischemia/reperfusion (I/R) is a pathological process that occurs in numerous organs throughout the human body, and it is frequently associated with severe cellular damage and death.
Hong-fa Yan +3 more
semanticscholar +1 more source
Nature Communications, 2018 Proinflammatory eicosanoids (prostaglandins and leukotrienes) and specialized pro-resolving mediators (SPM) are temporally regulated during infections.
Oliver Werz +7 more
doaj +1 more source
Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury. [PDF]
, 2020 ObjectivesCerebral ischemia/reperfusion (IR) drives oxidative stress and injurious metabolic processes that lead to redox imbalance, inflammation, and tissue damage. However, the key mediators of reperfusion injury remain unclear, and therefore, there is
Cabrales, Pedro +5 more
core
Transient limb ischemia induces remote ischemic preconditioning in vivo [PDF]
, 2002 Background-Ischemic preconditioning reduces local tissue injury caused by subsequent ischemia-reperfusion (IR), but may also have a salutary effect on IR injury of tissues remote from those undergoing preconditioning.
Hoschtitzky, JA +9 more
core +1 more source
Postconditioning: Reperfusion of “reperfusion injury” after hibernation [PDF]
Cardiovascular Research, 2006 The newly developed concept of postconditioning as a way of reducing reperfusion injury has been receiving much attention in the literature, both in basic science and clinical circles. Cardiovascular Research will be hosting a Spotlight Issue entitled “ Cardiac Protection by Pre- and Postconditioning ” in May of this year.
Hans Michael Piper, David Garcia-Dorado
openaire +3 more sources
Protection by 20-5,14-HEDGE Against Surgically-Induced Ischemia Reperfusion Lung Injury in Rats [PDF]
, 2012 Background We previously reported that the cytochrome P450 product 20-hydroxyeicosatetraenoic acid has prosurvival effects in pulmonary artery endothelial cells and ex vivo pulmonary arteries.
Ali, Irshad +6 more
core +2 more sources
Ischemia-Reperfusion Injury in Stroke [PDF]
Interventional Neurology, 2012 Despite ongoing advances in stroke imaging and treatment, ischemic and hemorrhagic stroke continue to debilitate patients with devastating outcomes at both the personal and societal levels. While the ultimate goal of therapy in ischemic stroke is geared towards restoration of blood flow, even when mitigation of initial tissue hypoxia is successful ...
Nour, May +2 more
openaire +5 more sources
Lipid Mediator Informatics and Proteomics in Inflammation-Resolution
The Scientific World Journal, 2006 Lipid mediator informatics is an emerging area denoted to the identification of bioactive lipid mediators (LMs) and their biosynthetic profiles and pathways.
Yan Lu +3 more
doaj +1 more source