Results 1 to 10 of about 205,704 (259)

Deep exploration of the TCR CDR3β repertoire specific for viral CD4 T-cell epitopes inside the circulating T-cell repertoire [PDF]

Frontiers in Immunology
IntroductionThis study provides an in-depth analysis of the diversity of the CD4 TCR CDR3β repertoire specific to influenza A (HA) and Epstein-Barr virus (EBNA) epitopes.MethodsEpitope-specific CD4 T cells from 13 healthy donors were enriched using a ...
Gautier Lhomme, Rémi Giraudet, Valéria Porcheddu, Evelyne Correia, Robert Olaso, Stephane Hua, Bernard Maillere   +6 more
doaj   +2 more sources

Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment

Journal for ImmunoTherapy of Cancer, 2023
Background High-risk human papillomavirus (HPV) is a primary cause of an increasing number of oropharyngeal squamous cell carcinomas (OPSCCs). The viral etiology of these cancers provides the opportunity for antigen-directed therapies that are restricted
Christine McInnis, Lakshmi Srinivasan, Anthony J Coyle, Shilpa Bhatia, Glenn J Hanna, Ann Marie Egloff, Brinda Vijaykumar, Qiaomu Tian, Yanbo Sun, Del Leistritz-Edwards, Charles T Quinn, Ravi Uppaluri, Daniel C Pregibon   +12 more
doaj   +1 more source

SOLUTION REPERTOIRE

DS 110: Proceedings of the 23rd International Conference on Engineering and Product Design Education (EPDE 2021), 2021
Research about design cognition acknowledges the importance of knowledge about exiting solutions. Designers tend to employ solution oriented thinking strategies; they generate idea’s starting from initial solutions - called primary generators; they are known to rely on episodic knowledge and precedent throughout the design process; and they iterate ...
Turnhout, Koen van, Smits, Aletta
openaire   +2 more sources

Idiotope-Driven T-Cell/B-Cell Collaboration-Based T-Cell Epitope Prediction Using B-Cell Receptor Repertoire Sequences in Infectious Diseases

Viruses, 2023
T-cell recognition of antigen epitopes is a crucial step for the induction of adaptive immune responses, and the identification of such T-cell epitopes is, therefore, important for understanding diverse immune responses and controlling T-cell immunity. A
Yukio Nakamura, Meng Ling Moi, Takashi Shiina, Tadasu Shin-I, Ryuji Suzuki   +4 more
doaj   +1 more source

Perturbations in the T cell receptor β repertoire during malaria infection in children: A preliminary study

Frontiers in Immunology, 2022
The changes occurring in the T cell repertoire during clinical malaria infection in children remain unknown. In this study, we undertook the first detailed comparative study of the T cell repertoire in African children with and without clinical malaria ...
Augustina Frimpong, Augustina Frimpong, Augustina Frimpong, Michael Fokuo Ofori, Michael Fokuo Ofori, Abdoelnaser M. Degoot, Kwadwo Asamoah Kusi, Kwadwo Asamoah Kusi, Buri Gershom, Jacob Quartey, Eric Kyei-Baafour, Nhi Nguyen, Wilfred Ndifon, Wilfred Ndifon   +13 more
doaj   +1 more source

Mapping what we know

Stridon, 2022
This article offers an outline of the literary translation flow from Turkish to Arabic between 1923 and 2005 based on a catalogue of translated literary works that were published in this period that was compiled for the purposes of this research.
Sare Rabia Öztürk
doaj   +1 more source

Repertoire

Victorian Literature and Culture, 2023
This keywords entry proposes that critical infrastructure studies allows us to better understand the cultural lives of nineteenth-century theatrical repertoires and asks: How would conceptualizing theatrical repertoire as an imaginative infrastructure help us understand its cultural legacies in our own day?
  +4 more sources

Ligao City’s Folklore: A Repertoire of Culture and Tradition, An Anthology of Indigenous Healing

Journal of Education, Management and Development Studies, 2022
The study is centered on the narratives on indigenous healing practices of Ligao City, Albay province, Philippines. It gathered genres, documented repertoire, validated text authenticity, translated texts into vernacular, and classified the typology of ...
Anacito Dematera
doaj   +1 more source

Pandemic, Epidemic, Endemic: B Cell Repertoire Analysis Reveals Unique Anti-Viral Responses to SARS-CoV-2, Ebola and Respiratory Syncytial Virus

Frontiers in Immunology, 2022
Immunoglobulin gene heterogeneity reflects the diversity and focus of the humoral immune response towards different infections, enabling inference of B cell development processes.
Alexander Stewart, Emma Sinclair, Joseph Chi-Fung Ng, Joselli Silva O’Hare, Joselli Silva O’Hare, Audrey Page, Ilaria Serangeli, Christian Margreitter, Federica Orsenigo, Federica Orsenigo, Katherine Longman, Cecile Frampas, Catia Costa, Holly-May Lewis, Nora Kasar, Bryan Wu, David Kipling, Peter JM Openshaw, Christopher Chiu, J Kenneth Baillie, Janet T. Scott, Malcolm G. Semple, Melanie J. Bailey, Franca Fraternali, Deborah K. Dunn-Walters   +24 more
doaj   +1 more source

Different Somatic Hypermutation Levels among Antibody Subclasses Disclosed by a New Next-Generation Sequencing-Based Antibody Repertoire Analysis

Frontiers in Immunology, 2017
A diverse antibody repertoire is primarily generated by the rearrangement of V, D, and J genes and subsequent somatic hypermutation (SHM). Class-switch recombination (CSR) produces various isotypes and subclasses with different functional properties ...
Kazutaka Kitaura, Hiroshi Yamashita, Hitomi Ayabe, Tadasu Shini, Tadasu Shini, Takaji Matsutani, Ryuji Suzuki, Ryuji Suzuki   +7 more
doaj   +1 more source