Results 161 to 170 of about 705,796 (337)

Advances in Invertebrate Biohybrid Robotics: Leveraging Nature for Locomotion and Sensing in Engineered Systems

Advanced Intelligent Systems, EarlyView.
This review explores invertebrate biohybrid robots that integrate living organisms—such as insects, jellyfish, spiders, and sea slugs—into robotic systems for locomotion, sensing, and actuation. The advantages in efficiency and cost, discuss control, and power challenges are highlighted, and future considerations to guide the development of sustainable,
Charles J. Fraga, Matticus S. Brown, Nicole W. Xu   +2 more
wiley   +1 more source

Exploring Skill Generalization with an Extra Robotic Arm for Motor Augmentation

Advanced Intelligent Systems, EarlyView.
Extra robotic arms promise to augment human motor functions during multitasking. Herein, diaphragmatic‐controlled extra robotic arm (XRA) is investigated, demonstrating significant performance improvements—true functional augmentation—in trimanual tasks. However, limited generalization to tasks requiring fine motor skills is identified.
Daniel Leal Pinheiro, Giulia Dominijanni, Francesca Paola Maenza, Hugo Dirat, Solaiman Shokur, Silvestro Micera   +5 more
wiley   +1 more source

Regioselective C─H Functionalization by the Combination of Enzymatic and Chemocatalytic Reactions in Water

Angewandte Chemie, EarlyView.
H3CP contributes to sustainable synthesis by integrating regioselective enzymatic halogenation, Pd‐catalyzed Heck coupling, and enzymatic hydrolysis. TPGS‐705‐M micelles enable the Pd‐catalyzed step, allowing seamless compatibility with enzymatic reactions in one vessel under aqueous conditions.
Ran Zhu, Xuhua Mo, Tanja Gulder, Tobias A. M. Gulder   +3 more
wiley   +2 more sources

Comparison of the fetal and adult functional B cell repertoires by analysis of VH gene family expression.

, 1988
Hyun Do Jeong, Judy M. Teale
openalex   +1 more source

Integrative Genomic and Transcriptomic Analysis Reveals Targetable Vulnerabilities in Angioimmunoblastic T‐Cell Lymphoma

American Journal of Hematology, EarlyView.
ABSTRACT Nodal follicular helper T‐cell (TFH) lymphoma of the angioimmunoblastic (AITL) subtype has a dismal prognosis. Using whole‐exome sequencing (n = 124), transcriptomic (n = 78), and methylation (n = 40) analysis, we identified recurrent mutations in known epigenetic drivers (TET2, DNMT3A, IDH2R172) and novel ones (TET3, KMT2D).
Alyssa Bouska, Weiwei Zhang, Sunandini Sharma, Harald Holte, Rauf A. Shah, Waseem G. Lone, Mahfuza Afroz Soma, Ruimeng Yang, Xuxiang Liu, Syed Mehmood, Ravneet Singh Chawla, Luca Vincenzo Cappelli, Danilo Fiore, Qiang Gong, Tayla B. Heavican‐Foral, Jeffrey J. Cannatella, Catalina Amador, Aiza Arif, Lynette M. Smith, Soon Thye Lim, Choon Kiat Ong, Andrew L. Feldman, Ming‐Qing Du, Anamarija M. Perry, Laurence de Leval, Timothy C. Greiner, Kai Fu, Gunhild Trøen, Daniel Vodák, Sigve Nakken, Jan Delabie, David Weinstock, Stefano Pileri, Antonella Laginestra, KyeongJin Kim, Utpal Pajvani, Julie M. Vose, Dennis D. Weisenburger, Steven M. Horwitz, Sandeep Dave, Joseph Khoury, Giorgio Inghirami, Wing C. Chan, Javeed Iqbal   +43 more
wiley   +1 more source

Small Molecule‐Induced Alterations of Protein Polyubiquitination Revealed by Mass‐Spectrometric Ubiquitome Analysis

Angewandte Chemie, EarlyView.
To monitor small molecule‐induced changes in protein polyubiquitination in an unbiased manner, we employ enrichment through tandem ubiquitin binding entities coupled to LC‐MS/MS analysis (TUBE‐MS). By applying the workflow to PROTAC, p97‐ and deubiquitinase‐inhibitor treatment of cells, we demonstrate its broad applicability and reveal the induction of
Siska Führer, Kai Gallant, Farnusch Kaschani, Markus Kaiser, Petra Janning, Herbert Waldmann, Malte Gersch   +6 more
wiley   +2 more sources

Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans. [PDF]

, 1992
Ermanno Ciccone, Daniela Pende, O Viale, C Di Donato, G. Tripodi, Anna Maria Orengo, John Guardiola, Alessandro Moretta, Lorenzo Moretta   +8 more
openalex   +1 more source

Perspectives on the Current and Future State of Artificial Intelligence in Medical Genetics

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Artificial intelligence (AI) is rapidly transforming numerous aspects of daily life, including clinical practice and biomedical research. In light of this rapid transformation, and in the context of medical genetics, we assembled a group of leaders in the field to respond to the question about how AI is affecting, and especially how AI will ...
Benjamin D. Solomon, Morgan Cheatham, Thales A. C. de Guimarães, Dat Duong, Melissa A. Haendel, Tzung‐Chien Hsieh, Behnam Javanmardi, Britt Johnson, Peter Krawitz, Paul Kruszka, Tim Laurent, Ni‐Chung Lee, Kirsty McWalter, Michel Michaelides, Klaus Mohnike, Nikolas Pontikos, Maria J. Guillen Sacoto, Yousif J. Shwetar, Vincent D. Ustach, Rebekah L. Waikel, William Woof   +20 more
wiley   +1 more source

Conditional Stabilization of the Hypoxia‐Inducible Factor HIF1α— Photoswitchable Stapled Peptides Prevent Elongin BC–Mediated Degradation

Angewandte Chemie, EarlyView.
Visible‐light photoswitchable peptides enable the stabilization of the hydroxylated hypoxia transcription factor 1α (HIF1α—OH) by targeting the pVHL‐EloBC interaction. Significant differences in conformation, binding, and transcription of HIF‐targeted genes between the photostationary states (PSS) were demonstrated.
Van Tuan Trinh, Sabrina Fischer, Lei Zhang, Heiko Geisler, Belen Pardo, Robert Liefke, Frank Abendroth, Olalla Vázquez   +7 more
wiley   +2 more sources

Editorial: Immune system modeling and analysis

Frontiers in Immunology, 2014
Ramit eMehr
doaj   +1 more source