Results 11 to 20 of about 889,250 (400)

Deep exploration of the TCR CDR3β repertoire specific for viral CD4 T-cell epitopes inside the circulating T-cell repertoire [PDF]

Frontiers in Immunology
IntroductionThis study provides an in-depth analysis of the diversity of the CD4 TCR CDR3β repertoire specific to influenza A (HA) and Epstein-Barr virus (EBNA) epitopes.MethodsEpitope-specific CD4 T cells from 13 healthy donors were enriched using a ...
Gautier Lhomme, Rémi Giraudet, Valéria Porcheddu, Evelyne Correia, Robert Olaso, Stephane Hua, Bernard Maillere   +6 more
doaj   +2 more sources

Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment

Journal for ImmunoTherapy of Cancer, 2023
Background High-risk human papillomavirus (HPV) is a primary cause of an increasing number of oropharyngeal squamous cell carcinomas (OPSCCs). The viral etiology of these cancers provides the opportunity for antigen-directed therapies that are restricted
Christine McInnis, Lakshmi Srinivasan, Anthony J Coyle, Shilpa Bhatia, Glenn J Hanna, Ann Marie Egloff, Brinda Vijaykumar, Qiaomu Tian, Yanbo Sun, Del Leistritz-Edwards, Charles T Quinn, Ravi Uppaluri, Daniel C Pregibon   +12 more
doaj   +1 more source

SOLUTION REPERTOIRE

DS 110: Proceedings of the 23rd International Conference on Engineering and Product Design Education (EPDE 2021), 2021
Research about design cognition acknowledges the importance of knowledge about exiting solutions. Designers tend to employ solution oriented thinking strategies; they generate idea’s starting from initial solutions - called primary generators; they are known to rely on episodic knowledge and precedent throughout the design process; and they iterate ...
Turnhout, Koen van, Smits, Aletta
openaire   +2 more sources

Not a First Language but One Repertoire: Translanguaging as a Decolonizing Project

RELC Journal : A Journal of Language Teaching and Research in Southeast Asia, 2022
Translanguaging has opened up spaces to recognize the dynamic multilingualism of students in classrooms taught in dominant languages, and problematized concepts such as ‘additive bilingualism’.
Li Wei, Ofelia García
semanticscholar   +1 more source

Idiotope-Driven T-Cell/B-Cell Collaboration-Based T-Cell Epitope Prediction Using B-Cell Receptor Repertoire Sequences in Infectious Diseases

Viruses, 2023
T-cell recognition of antigen epitopes is a crucial step for the induction of adaptive immune responses, and the identification of such T-cell epitopes is, therefore, important for understanding diverse immune responses and controlling T-cell immunity. A
Yukio Nakamura, Meng Ling Moi, Takashi Shiina, Tadasu Shin-I, Ryuji Suzuki   +4 more
doaj   +1 more source

A cell atlas of human thymic development defines T cell repertoire formation

Science, 2020
Thymus development, cell by cell The human thymus is the organ responsible for the maturation of many types of T cells, which are immune cells that protect us from infection.
Jong-Eun Park, R. Botting, Cecilia Domínguez Conde, Dorin-Mirel Popescu, M. Lavaert, Daniel J. Kunz, Issac Goh, Emily Stephenson, Roberta Ragazzini, E. Tuck, A. Wilbrey-Clark, Kenny Roberts, Veronika R. Kedlian, J. Ferdinand, Xiaoling He, S. Webb, Daniel Maunder, N. Vandamme, Krishnaa T. A. Mahbubani, K. Polański, L. Mamanova, L. Bolt, D. Crossland, F. de Rita, A. Fuller, A. Filby, G. Reynolds, D. Dixon, K. Saeb‐Parsy, S. Lisgo, D. Henderson, R. Vento-Tormo, O. Bayraktar, R. Barker, K. Meyer, Y. Saeys, P. Bonfanti, S. Behjati, M. Clatworthy, T. Taghon, M. Haniffa, S. Teichmann   +41 more
semanticscholar   +1 more source

Modern Hopfield Networks and Attention for Immune Repertoire Classification [PDF]

bioRxiv, 2020
A central mechanism in machine learning is to identify, store, and recognize patterns. How to learn, access, and retrieve such patterns is crucial in Hopfield networks and the more recent transformer architectures. We show that the attention mechanism of
Michael Widrich, Bernhard Schäfl, Milena Pavlović, Hubert Ramsauer, Lukas Gruber, Markus Holzleitner, Johannes Brandstetter, G. K. Sandve, V. Greiff, Sepp Hochreiter, G. Klambauer   +10 more
semanticscholar   +1 more source

Perturbations in the T cell receptor β repertoire during malaria infection in children: A preliminary study

Frontiers in Immunology, 2022
The changes occurring in the T cell repertoire during clinical malaria infection in children remain unknown. In this study, we undertook the first detailed comparative study of the T cell repertoire in African children with and without clinical malaria ...
Augustina Frimpong, Augustina Frimpong, Augustina Frimpong, Michael Fokuo Ofori, Michael Fokuo Ofori, Abdoelnaser M. Degoot, Kwadwo Asamoah Kusi, Kwadwo Asamoah Kusi, Buri Gershom, Jacob Quartey, Eric Kyei-Baafour, Nhi Nguyen, Wilfred Ndifon, Wilfred Ndifon   +13 more
doaj   +1 more source

Longitudinal analysis reveals age-related changes in the T cell receptor repertoire of human T cell subsets

Journal of Clinical Investigation, 2022
A diverse T cell receptor (TCR) repertoire is essential for protection against a variety of pathogens, and TCR repertoire size is believed to decline with age.
Xiaoping Sun, Thomas Nguyen, A. Achour, Annette Ko, Jeffrey Cifello, Chen Ling, Jay Sharma, T. Hiroi, Yongqing Zhang, C. Chia, William H Wood III, Wells W. Wu, L. Zukley, Je-Nie Phue, K. Becker, Rong‐Fong Shen, L. Ferrucci, N. Weng   +17 more
semanticscholar   +1 more source

Mapping what we know

Stridon, 2022
This article offers an outline of the literary translation flow from Turkish to Arabic between 1923 and 2005 based on a catalogue of translated literary works that were published in this period that was compiled for the purposes of this research.
Sare Rabia Öztürk
doaj   +1 more source