Results 41 to 50 of about 3,159,718 (373)
Is There a Replication Crisis in Finance?
Social Science Research Network, 2021 Several papers argue that financial economics faces a replication crisis because the majority of studies cannot be replicated or are the result of multiple testing of too many factors. We develop and estimate a Bayesian model of factor replication, which
Theis Ingerslev Jensen +2 more
semanticscholar +1 more source
Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication. [PDF]
, 2017 A key goal of diabetes research is to develop treatments to safely promote human ß-cell replication. It has recently become appreciated that activation of γ-aminobutyric acid receptors (GABA-Rs) on ß-cells can promote their survival and replication.
Dang, Hoa +3 more
core +1 more source
A quantitative model of the initiation of DNA replication in Saccharomyces cerevisiae predicts the effects of system perturbations. [PDF]
, 2012 BackgroundEukaryotic cell proliferation involves DNA replication, a tightly regulated process mediated by a multitude of protein factors. In budding yeast, the initiation of replication is facilitated by the heterohexameric origin recognition complex ...
DaSilva, Lance F +6 more
core +3 more sources
bioRxiv, 2020 The sudden emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the end of 2019 from the Chinese province of Hubei and its subsequent pandemic spread highlight the importance of understanding the full molecular details of ...
N. Ogando +11 more
semanticscholar +1 more source
Checkpoint-Dependent Regulation of Origin Firing and Replication Fork Movement in Response to DNA Damage in Fission Yeast [PDF]
, 2009 To elucidate the checkpoint mechanism responsible for slowing passage through S phase when fission yeast cells are treated with the DNA-damaging agent methyl methanesulfonate (MMS), we carried out two-dimensional gel analyses of replication intermediates
Huberman, Joel A., Kumar, Sanjay
core +3 more sources
ACM Computing Surveys, 2005 Data replication is a key technology in distributed systems that enables higher availability and performance. This article surveys optimistic replication algorithms. They allow replica contents to diverge in the short term to support concurrent work practices and tolerate failures in low-quality communication links. The importance of such techniques is
Saito, Yasushi, Shapiro, Marc
openaire +3 more sources
Causality and replication in concurrent processes [PDF]
, 2003 The replication operator was introduced by Milner for obtaining a simplified description of recursive processes. The standard interleaving semantics denotes the replication of a process P, written !P, a shorthand for its unbound parallel composition ...
A. Kiehn +15 more
core +1 more source
Drf1-dependent Kinase Interacts with Claspin through a Conserved Protein Motif [PDF]
, 2010 The Dbf4/Drf1-dependent kinase (DDK) is required for the initiation of DNA replication in eukaryotes. Another protein, Claspin, mediates the activation of a cellular checkpoint response to stalled replication forks and is also a regulator of replication.
Aparicio +48 more
core +3 more sources
mBio, 2021 Although combination antiretroviral (ARV) therapy is highly effective in controlling the progression of HIV disease, drug resistance can be a major obstacle. Recent findings suggest that resistance can develop without ARV target gene mutations.
Yuta Hikichi +7 more
doaj +1 more source
Cyclin E/CDK2: DNA Replication, Replication Stress and Genomic Instability
Frontiers in Cell and Developmental Biology, 2021 DNA replication must be precisely controlled in order to maintain genome stability. Transition through cell cycle phases is regulated by a family of Cyclin-Dependent Kinases (CDKs) in association with respective cyclin regulatory subunits. In normal cell
Rafaela Fagundes, L. K. Teixeira
semanticscholar +1 more source