A new decentralized periodic replication strategy for dynamic data grids [PDF]
Data grids provide scalable infrastructure for storage resource and data files management, which support data-intensive applications that need to access to huge amount of data stored at distributed locations around the world.
Charrada, Faouzi Ben, Chettaoui, Hanene
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Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins
Viral envelope glycoproteins are an important structural component on the surfaces of enveloped viruses that direct virus binding and entry and also serve as targets for the host adaptive immune response.
Cheng Man Lun +4 more
doaj +1 more source
Replication fork collisions cause pathological chromosomal amplification in cells lacking RecG DNA translocase [PDF]
This is an open access article, shared under a Creative Commons licence. Copyright © 2009 The Authors.Duplication and transmission of chromosomes require precise control of chromosome replication and segregation.
Lloyd, RG +4 more
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Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation
The Rad53 DNA checkpoint protein kinase plays multiple roles in the budding yeast cell response to DNA replication stress. Key amongst these is its enigmatic role in safeguarding DNA replication forks.
Allison W McClure, John FX Diffley
doaj +1 more source
DNAReplication: a database of information and resources for the eukaryotic DNA replication community [PDF]
DNAReplication (at http://www.dnareplication.net) has been set up as a freely available single resource to facilitate access to information on eukaryotic DNA replication.
Cotterill, S +4 more
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IFITM3 Reduces Retroviral Envelope Abundance and Function and Is Counteracted by glycoGag
Interferon-induced transmembrane (IFITM) proteins are encoded by many vertebrate species and exhibit antiviral activities against a wide range of viruses.
Yadvinder S. Ahi +6 more
doaj +1 more source
Here the authors describe multiple structures of the replicative helicase MCM2-7 in complex with Dbf4-dependent kinase (DDK). These structures reveal why the kinase specifically recognizes the MCM2-7 double-hexamer over the single-hexamer and explain how
Almutasem Saleh +9 more
doaj +1 more source
USF binding sequences from the HS4 insulator element impose early replication timing on a vertebrate replicator [PDF]
The nuclear genomes of vertebrates show a highly organized program of DNA replication where GC-rich isochores are replicated early in S-phase, while AT-rich isochores are late replicating.
Chilaka, S. +20 more
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Efficient support of virus-like particle assembly by the HIV-1 packaging signal
The principal structural component of a retrovirus particle is the Gag protein. Retroviral genomic RNAs contain a ‘packaging signal’ (‘Ψ') and are packaged in virus particles with very high selectivity.
Mauricio Comas-Garcia +5 more
doaj +1 more source
The dynamics of replication licensing in live Caenorhabditis elegans embryos [PDF]
Accurate DNA replication requires proper regulation of replication licensing, which entails loading MCM-2-7 onto replication origins. In this paper, we provide the first comprehensive view of replication licensing in vivo, using video microscopy of ...
Blow, J. Julian; id_orcid +10 more
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