Results 21 to 30 of about 1,350,402 (318)

IFITM3 Reduces Retroviral Envelope Abundance and Function and Is Counteracted by glycoGag

open access: yesmBio, 2020
Interferon-induced transmembrane (IFITM) proteins are encoded by many vertebrate species and exhibit antiviral activities against a wide range of viruses.
Yadvinder S. Ahi   +6 more
doaj   +1 more source

Restriction of Influenza A Virus by SERINC5

open access: yesmBio, 2022
Serine incorporator 5 (Ser5), a transmembrane protein, has recently been identified as a host antiviral factor against human immunodeficiency virus (HIV)-1 and gammaretroviruses like murine leukemia viruses (MLVs). It is counteracted by HIV-1 Nef and MLV
Kin Kui Lai   +5 more
doaj   +1 more source

replication

open access: yes, 2022
Individual SPM and VOI files, for the replication sample.
David Coynel (13821943)
core   +1 more source

The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer

open access: yesNature Communications, 2022
Here the authors describe multiple structures of the replicative helicase MCM2-7 in complex with Dbf4-dependent kinase (DDK). These structures reveal why the kinase specifically recognizes the MCM2-7 double-hexamer over the single-hexamer and explain how
Almutasem Saleh   +9 more
doaj   +1 more source

Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins

open access: yesmBio, 2021
Viral envelope glycoproteins are an important structural component on the surfaces of enveloped viruses that direct virus binding and entry and also serve as targets for the host adaptive immune response.
Cheng Man Lun   +4 more
doaj   +1 more source

USF binding sequences from the HS4 insulator element impose early replication timing on a vertebrate replicator [PDF]

open access: yes, 2012
The nuclear genomes of vertebrates show a highly organized program of DNA replication where GC-rich isochores are replicated early in S-phase, while AT-rich isochores are late replicating.
Chilaka, S.   +20 more
core   +1 more source

Optimistic replication [PDF]

open access: yesACM Computing Surveys, 2005
Data replication is a key technology in distributed systems that enables higher availability and performance. This article surveys optimistic replication algorithms. They allow replica contents to diverge in the short term to support concurrent work practices and tolerate failures in low-quality communication links. The importance of such techniques is
Saito, Yasushi, Shapiro, Marc
openaire   +2 more sources

The dynamics of replication licensing in live Caenorhabditis elegans embryos [PDF]

open access: yes, 2012
Accurate DNA replication requires proper regulation of replication licensing, which entails loading MCM-2-7 onto replication origins. In this paper, we provide the first comprehensive view of replication licensing in vivo, using video microscopy of ...
Blow, J. Julian; id_orcid   +10 more
core   +1 more source

Efficient support of virus-like particle assembly by the HIV-1 packaging signal

open access: yeseLife, 2018
The principal structural component of a retrovirus particle is the Gag protein. Retroviral genomic RNAs contain a ‘packaging signal’ (‘Ψ') and are packaged in virus particles with very high selectivity.
Mauricio Comas-Garcia   +5 more
doaj   +1 more source

Genome organization of DNA replication timing and its link to chromatin and transcription [PDF]

open access: yes, 2008
The replication of the genome is a highly organized process. Not every sequence replicates at the same time, instead some genes replicate early, while others replicate later during S phase.
Schwaiger, Michaela
core   +1 more source

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