Results 251 to 260 of about 1,088,807 (293)

Replication Initiative: Dangerous Logic

Science, 2012
The comments voiced by some scientists in response to Brian Nosek's project to systematically replicate studies in social psychology (“Psychology's bold initiative,” S. Carpenter, News Focus, 30 March, p. [1558][1]) are deeply worrisome. Reluctance to replicate data in a given field of science because it might harm the field's public image among other ...
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A turnstile for initiation of DNA replication

Trends in Cell Biology, 1991
The progress of a cell through its growth cycle is a multifaceted process; so far we have seen only a glimpse of the complex interplay between the macromolecules performing and regulating the different steps involved. In most organisms, control mechanisms ensure that all chromosomal DNA sequences are replicated once, and only once, between two cell ...
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Replication Initiative: Prioritize Publication

Science, 2012
The Open Science Collaboration's new platform for publishing the results of replicated experiments is commendable and indeed bold (“Psychology's bold initiative,” S. Carpenter, News Focus, 30 March, p. [1558][1]). However, as convenient and efficient as this platform may prove to be, it should not distract us from the need to revise and extend more ...
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Replication initiation: Implications in genome integrity

DNA Repair, 2021
In every cell cycle, billions of nucleotides need to be duplicated within hours, with extraordinary precision and accuracy. The molecular mechanism by which cells regulate the replication event is very complicated, and the entire process begins way before the onset of S phase. During the G1 phase of the cell cycle, cells prepare by assembling essential
Yo-Chuen, Lin, Supriya G, Prasanth
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DNA Replication Initiation

2009
DNA replication is fundamental to cellular life on earth, and replication initiation provides the primary point of control over this process. Replication initiation in all organisms involves the interaction of initiator proteins with one or more origins of replication in the DNA, with subsequent regulated assembly of two replisome complexes at each ...
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Replication Initiative: Beware Misinterpretation

Science, 2012
Two new initiatives are exploring the reproducibility of findings within psychology (“Psychology's bold initiative,” S. Carpenter, News Focus, 30 March, p. [1558][1]). One approach provides an online outlet for replication attempts, regardless of success or failure.
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Initiation of Viral DNA Replication

1988
Publisher Summary This chapter focuses on the mechanisms involved in initiation of animal virus DNA replication. This step is of fundamental importance because it represents the central point of control of the replication process. Two of the best-characterized viruses, adenovirus and SV40, are discussed as examples of viruses that normally multiply ...
T J, Kelly, M S, Wold, J, Li
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Initiation of DNA Replication in the Archaea

2017
Organisms within the archaeal domain of life possess a simplified version of the eukaryotic DNA replication machinery. While some archaea possess a bacterial-like mode of DNA replication with single origins of replication per chromosome, the majority of species characterized to date possess chromosomes with multiple replication origins.
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Initiation of DNA replication in multicellular eukaryotes

Journal of Structural Biology, 2002
Three questions central to understanding the initiation of DNA replication in eukaryotes are: (1) Does DNA synthesis begin at a defined place? (2) What determines replication initiation sites? (3) What regulates an origin to fire only once per cell cycle?
Susan Gerbi
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Initiation of Chromosomal Replication

2014
The complex process of bacterial chromosomal replication can be divided into several stages: initiation, priming of chain starts, chain elongation, and termination. Since much of what is known about the initiation of bacterial chromosomal replication comes from studies of Escherichia coli, this chapter concentrates on initiation in that organism.
Johanna Eltz Camara, Elliott Crooke
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