Results 51 to 60 of about 817,676 (313)

Human papillomavirus 16 L2 inhibits the transcriptional activation function, but not the DNA replication function, of HPV-16 E2 [PDF]

, 2005
In this study we analysed the outcome of the interaction between HPV-16 L2 and E2 on the transactivation and DNA replication functions of E2. When E2 was expressed on its own, it transactivated a number of E2-responsive promoters but co-expression of L2 ...
Morgan, I.M., Cordano, P., Taylor, E.R., Everett, R., R. Everett, A. Okoye, M.S. Campo, P. Cordano, E.R. Taylor, Campo, M.S., I.M. Morgan, Okoye, A.   +11 more
core   +1 more source

Eukaryotic RNA binding protein hnRNPH1 suppresses influenza A virus replication through interaction with virus NS1 protein

Emerging Microbes and Infections
The NS1 protein of influenza A virus (IAV) is a multi-functional protein which can antagonize host immune system and facilitate viral replication by interacting with host factors.
Jinyu Wang, Yang Zhang, Lishan Sun, Zihan Wang, Cui Hao, Wei Wang   +5 more
doaj   +1 more source

Unravelling the structure of viral replication complexes at super-resolution [PDF]

, 2013
This work was supported by Biotechnology and Biomedical Sciences Research Council grant BB/H018719/1During infection, many RNA viruses produce characteristic inclusion bodies that contain both viral and host components.
Karl J. Oparka, Tilsner, Jens, Jens eTilsner, Johannes Liesche, Johannes eLiesche, Olga Linnik, Liesche, Johannes, Olga eLinnik, Karl eOparka, Oparka, Karl J, Jens Tilsner, Oparka, Karl J., Linnik, Olga   +12 more
core   +1 more source

Differential Binding of Replication Proteins across the Human c-myc Replicator [PDF]

Molecular and Cellular Biology, 2006
The binding of the prereplication complex proteins Orc1, Orc2, Mcm3, Mcm7, and Cdc6 and the novel DNA unwinding element (DUE) binding protein DUE-B to the endogenous human c-myc replicator was studied by chromatin immunoprecipitation. In G(1)-arrested HeLa cells, Mcm3, Mcm7, and DUE-B were prominent near the DUE, while Orc1 and Orc2 were least abundant
Maloy, Ghosh, Michael, Kemp, Guoqi, Liu, Marion, Ritzi, Aloys, Schepers, Michael, Leffak   +5 more
openaire   +2 more sources

Inhibition of HIV-1 replication by small interfering RNAs directed against Glioma Pathogenesis Related Protein (GliPR) expression [PDF]

, 2010
Background: Previously, we showed that glioma pathogenesis related protein (GliPR) is induced in CEM T cells upon HIV-1 infection in vitro. To examine whether GliPR plays a role as HIV dependency factor (HDF), we tested the effect of GliPR suppression by
Scheuring Urban J, Oliver G Ottmann, Dietrich, Ursula, Capalbo Gianni, Scheuring, Urban J., Ursula Dietrich, Ottmann, Oliver G., Dietrich Ursula, Gianni Capalbo, Urban J Scheuring, Hoelzer, Dieter (Prof. Dr.), Müller-Kuller Thea, Hoelzer Dieter, Ottmann Oliver G, Dieter Hoelzer, Thea Müller-Kuller, Capalbo, Gianni, Müller-Kuller, Thea   +17 more
core   +1 more source

NDRG1 facilitates lytic replication of Kaposi's sarcoma-associated herpesvirus by maintaining the stability of the KSHV helicase.

PLoS Pathogens, 2021
The presumed DNA helicase encoded by ORF44 of Kaposi's sarcoma-associated herpesvirus (KSHV) plays a crucial role in unwinding viral double-stranded DNA and initiating DNA replication during lytic reactivation.
Lianghui Dong, Jiazhen Dong, Min Xiang, Ping Lei, Zixian Li, Fang Zhang, Xiaoyi Sun, Danping Niu, Lei Bai, Ke Lan   +9 more
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

GEMC1, a novel factor required for chromosomal DNA replication [PDF]

, 2009
In eukaryotic cells DNA replication begins from multiple origins. During the process of initiation, the DNA replication fork is established at each origin. In lower eukaryotes many factors required for chromosomal DNA replication have been identified.
Balestrini, A.
core  

The Toxoplasma gondii Plastid replication and Repair Enzyme complex, PREX [PDF]

, 2009
A plastid-like organelle, the apicoplast, is essential to the majority of medically and veterinary important apicomplexan protozoa including Toxoplasma gondii and Plasmodium.
Chen, C-Y., Henriquez, F L, Roberts, C. W., Chen, C.Y., Barrett, M.P., Chen, C-Y, Barrett, M. P., Roberts, C W, Henriquez, F. L., Doerig, C., Roberts, C.W., Roberts, Craig, Mukhopadhyay, A, Chen, C.-Y., Mukhopadhyay, A., Henriquez, F.L., Barrett, M P, Doerig, C   +17 more
core   +1 more source

Yeast Srs2 Helicase Promotes Redistribution of Single-Stranded DNA-Bound RPA and Rad52 in Homologous Recombination Regulation

Cell Reports, 2017
Srs2 is a super-family 1 helicase that promotes genome stability by dismantling toxic DNA recombination intermediates. However, the mechanisms by which Srs2 remodels or resolves recombination intermediates remain poorly understood.
Luisina De Tullio, Kyle Kaniecki, Youngho Kwon, J. Brooks Crickard, Patrick Sung, Eric C. Greene   +5 more
doaj   +1 more source