Results 21 to 30 of about 1,062,480 (303)

Cellular location and activity of Escherichia coli RecG proteins shed light on the function of its structurally unresolved C-terminus [PDF]

, 2014
RecG is a DNA translocase encoded by most species of bacteria. The Escherichia coli protein targets branched DNA substrates and drives the unwinding and rewinding of DNA strands.
Abd Wahab, Akeel A. Mahdi, Al-Deib, Amy L. Upton, Atkinson, Bachmann, Bernhardt, Bolt, Brendler, Briggs, Briggs, Buss, Christian J. Rudolph, Datsenko, David S. Milner, Gari, Geoffrey S. Briggs, Gregg, Gupta, Hong, Jaktaji, Jane I. Grove, Lau, Lecointe, Lesterlin, Lia, Lloyd, Lloyd, Lloyd, Machwe, Mahdi, Mahdi, Mahdi, Mahdi, Manosas, Marians, McGlynn, McGlynn, McGlynn, McGlynn, McGlynn, McGlynn, McGlynn, Michel, Parsons, Pomerantz, Ralf, Robert G. Lloyd, Rocha, Rudolph, Rudolph, Rudolph, Rudolph, Seigneur, Sharples, Shereda, Singleton, Sun, Trautinger, Tsaneva, Vincent, Waldminghaus, West, Whitby, Whitby, Whitby, Whitby, Zacharias, Zhang   +68 more
core   +2 more sources

Up-regulation of glycolipid transfer protein by bicyclol causes spontaneous restriction of hepatitis C virus replication

Acta Pharmaceutica Sinica B, 2019
Bicyclol is a synthetic drug for hepatoprotection in clinic since 2004. Preliminary clinical observations suggest that bicyclol might be active against hepatitis C virus (HCV) with unknown mechanism.
Meng-Hao Huang, Hu Li, Rong Xue, Jianrui Li, Lihua Wang, Junjun Cheng, Zhouyi Wu, Wenjing Li, Jinhua Chen, Xiaoqin Lv, Qiang Li, Pei Lan, Limin Zhao, Yongfeng Yang, Zonggen Peng, Jiandong Jiang   +15 more
doaj   +1 more source

c-Myc accelerates S-phase and requires WRN to avoid replication stress. [PDF]

PLoS ONE, 2009
c-Myc interacts with components of the pre-replication complex and directly regulates DNA replication [1]. However the consequences of this novel c-Myc function on cell cycle dynamics and replication-associated damage are unknown.
Kristin Robinson, Nichaya Asawachaicharn, Denise A Galloway, Carla Grandori   +3 more
doaj   +1 more source

mRNA Display Design of Fibronectin-based Intrabodies That Detect and Inhibit Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein [PDF]

, 2009
The nucleocapsid (N) protein of severe acute respiratory syndrome (SARS) coronavirus plays important roles in both viral replication and modulation of host cell processes.
Amstutz, C. Anders Olson, Cardinale, Cardinale, Carlson, Carter, Chakrabarti, Chang, Chen, Elaine Wong, Enjuanes, Hongyu Deng, Hosse, Hsiang-I. Liao, Ja, Kawe, Koide, Lipovsek, Liu, Luo, Maynard, Milligan, Nizak, Olson, Olson, Rajpal, Ralph S. Baric, Ren Sun, Richard W. Roberts, Roberts, Roberts, Rota, Saikatendu, Satija, Seungmin Hwang, Stocks, Surjit, Vascotto, Visintin, Yount, Yu   +40 more
core   +4 more sources

Inhibition of protein kinases C prevents murine cytomegalovirus replication

Journal of General Virology, 2005
For successful establishment of infection and initiation of the replication cycle, murine cytomegalovirus (MCMV) utilizes cellular structures and functions, including cell-membrane penetration, capsid dismantling and cytosolic transport of viral DNA into the nucleus. These early events of MCMV infections are dependent on cellular regulatory mechanisms,
Kučić, Natalia, Mahmutefendić Lučin, Hana, Lučin, Pero   +2 more
openaire   +3 more sources

Important roles of C-terminal residues in degradation of capsid protein of classical swine fever virus

Virology Journal, 2019
Background Capsid (C) protein plays an important role in the replication of classical swine fever virus (CSFV). The ubiquitin proteasome system (UPS) involves in replication of many viruses via modulation of viral proteins.
Yuming Chen, Erpeng Zhu, Shuangqi Fan, Hongxing Ding, Shengming Ma, Mengjiao Zhu, Shaofeng Deng, Jinding Chen, Mingqiu Zhao   +8 more
doaj   +1 more source

The V protein of canine distemper virus is required for virus replication in human epithelial cells. [PDF]

PLoS ONE, 2013
Canine distemper virus (CDV) becomes able to use human receptors through a single amino acid substitution in the H protein. In addition, CDV strains possessing an intact C protein replicate well in human epithelial H358 cells.
Noriyuki Otsuki, Yuichiro Nakatsu, Toru Kubota, Tsuyoshi Sekizuka, Fumio Seki, Kouji Sakai, Makoto Kuroda, Ryoji Yamaguchi, Makoto Takeda   +8 more
doaj   +1 more source

Inhibition of hepatitis C virus RNA replication by ISG15 does not require its conjugation to protein substrates by the HERC5 E3 ligase [PDF]

, 2015
Chronic infection of the liver by hepatitis C virus (HCV) induces a range of host factors including IFN-stimulated genes such as ISG15. ISG15 functions as an antiviral factor that limits virus replication. Previous studies have suggested that ISG15 could
Bamford, Connor G.G., Boutell, Chris, Domingues, Patricia, McLauchlan, John   +3 more
core   +2 more sources

Normal Replication of Vesicular Stomatitis Virus without C Proteins

Virology, 1996
The expression of two small basic proteins (C and C') encoded by a second open reading frame of the New Jersey serotype of vesicular stomatitis virus (VSV) P gene was reported previously (Spiropoulou and Nichol, J. Virol., 67, 3103-3110, 1993). Here we found that the Indiana serotype virus also expressed C and C' proteins from this reading frame.
KRETZSCHMAR, EVELYNE, PELUSO, RICHARD, SCHNELL, MATTHIAS J., WHITT, MICHAEL A., ROSE, JOHN K.   +4 more
openaire   +2 more sources

Inhibition of protein kinase C promotes dengue virus replication

Virology Journal, 2016
Dengue virus (DENV) is a member of the Flaviviridae family, transmitted to human via mosquito. DENV infection is common in tropical areas and occasionally causes life-threatening symptoms. DENV contains a relatively short positive-stranded RNA genome, which encodes ten viral proteins.
Noppakunmongkolchai, Warobon, Poyomtip, Teera, Jittawuttipoka, Thichakorn, Luplertlop, Natthanej, Sakuntabhai, Anavaj, Chimnaronk, Sarin, Jirawatnotai, Siwanon, Tohtong, Rutaiwan   +7 more
openaire   +3 more sources