Results 11 to 20 of about 7,873,006 (309)
Reporter gene assay for membrane fusion of extracellular vesicles. [PDF]
J Extracell Vesicles, 2021 Extracellular vesicles (EVs) secreted by living cells are expected to deliver biological cargo molecules, including RNA and proteins, to the cytoplasm of recipient cells.
Somiya M, Kuroda S.
europepmc +2 more sources
Enrichment of transgene integrations by transient CRISPR activation of a silent reporter gene [PDF]
Molecular Therapy: Methods & Clinical Development, 2023 CRISPR-Cas-mediated site-specific integration of transgenes by homology-directed repair (HDR) is challenging, especially in primary cells, where inferior editing efficiency may impede the development of gene- and cellular therapies.
Nanna S. Mikkelsen +4 more
doaj +2 more sources
Reporter Gene-Based qRT-PCR Assay for Rho-Dependent Termination In Vivo [PDF]
Cells, 2023 In bacteria, the Rho protein mediates Rho-dependent termination (RDT) by identifying a non-specific cytosine-rich Rho utilization site on the newly synthesized RNA. As a result of RDT, downstream RNA transcription is reduced.
Monford Paul Abishek N +3 more
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Magnetic Resonance Reporter Gene Imaging
Theranostics, 2012 Molecular imaging has undergone an explosive advancement in recent years, due to the tremendous research efforts made to understand and visualize biological processes.
Sheen-Woo Lee, Sang-Hoon Lee, Sandip Biswal
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Molecular Therapy: Oncolytics, 2021 Bioluminescence reporter gene imaging is a robust, high-throughput imaging modality that is useful for tracking cells and monitoring biological processes, both in cell culture and in small animals.
Maxim A. Moroz +10 more
doaj +1 more source
Frontiers in Oncology, 2021 BackgroundMicroRNAs (miRs) have been shown to be closely associated with the occurrence and development of tumors and to have potential as diagnostic and therapeutic targets.
Guangcheng Bao +31 more
doaj +1 more source
Biosensors, 2023 Reporter genes are important tools in many biological disciplines. The discovery of novel reporter genes is relatively rare. However, known reporter genes are constantly applied to novel applications.
Céline S. M. Richard +4 more
doaj +1 more source
StORF-Reporter: finding genes between genes
Nucleic Acids Research, 2022 Abstract Large regions of prokaryotic genomes are currently without any annotation, in part due to well-established limitations of annotation tools. For example, it is routine for genes using alternative start codons to be misreported or completely omitted.
Nicholas J Dimonaco +4 more
openaire +4 more sources
Journal of Nuclear Medicine, 2008 Noninvasive molecular imaging of dynamic processes has benefited tremendously from the use of reporter genes. These genes encode for proteins that emit light, bind radiolabeled probes, or, as covered in this review, modulate MRI contrast. Reporter genes play a pivotal role in monitoring cell trafficking, gene replacement therapy, protein-protein ...
Assaf A, Gilad +5 more
openaire +2 more sources