Results 41 to 50 of about 7,567,038 (395)

Simultaneous imaging of a lacZ-marked tumor and microvasculature morphology in vivo by dual-wavelength photoacoustic microscopy [PDF]

, 2008
Photoacoustic molecular imaging, combined with the reporter-gene technique, can provide a valuable tool for cancer research. The expression of the lacZ reporter gene can be imaged using photoacoustic imaging following the injection of X-gal, a ...
Li, Li, Maslov, Konstantin, Wang, Lihong V., Zemp, Roger J., Zhang, Hao F.   +4 more
core   +2 more sources

The use of the NIS reporter gene for optimizing oncolytic virotherapy

Expert Opinion on Biological Therapy, 2015
Introduction: Oncolytic viruses are experimental cancer therapies being translated to the clinic. They are unique in their ability to amplify within the body, therefore requiring careful monitoring of viral replication and biodistribution.
A. Miller, S. Russell
semanticscholar   +1 more source

Studying Membrane Biogenesis with a Luciferase-Based Reporter Gene Assay [PDF]

, 2008
To study the coordination of different lipid synthesis pathways during membrane biogenesis it is useful to work with an experimental system where membrane biogenesis occurs rapidly and in an inducible manner.
Nohturfft, A, Zhang, S
core   +2 more sources

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

BMC Developmental Biology, 2001
BackgroundSeveral Cre reporter strains of mice have been described, in which a lacZ gene is turned on in cells expressing Cre recombinase, as well as their daughter cells, following Cre-mediated excision of a loxP-flanked transcriptional "stop" sequence.
S. Srinivas, Tomoko Watanabe, Chyuan-Sheng Lin, C. William, Y. Tanabe, T. Jessell, F. Costantini   +6 more
semanticscholar   +1 more source

A Novel MitoTimer Reporter Gene for Mitochondrial Content, Structure, Stress, and Damage in Vivo*

Journal of Biological Chemistry, 2014
Background: Mitochondrial health is difficult to assess in vivo. Results: We have generated a reporter gene, MitoTimer, which targets mitochondria, and fluoresces green and shifts to red when oxidized, for assessment of mitochondrial content, structure ...
R. Laker, Peng Xu, K. Ryall, A. Sujkowski, Brandon M. Kenwood, Kristopher H Chain, Mei Zhang, M. Royal, Kyle L. Hoehn, M. Driscoll, P. Adler, R. Wessells, J. Saucerman, Zhen Yan   +13 more
semanticscholar   +1 more source

Mutational analysis of the gene start sequences of pneumonia virus of mice [PDF]

, 2007
The transcriptional start sequence of pneumonia virus of mice is more variable than that of the other pneumoviruses, with five different nine-base gene start (GS) sequences found in the PVM genome.
Dibben, Oliver, Easton, A. J. (Andrew J.)   +1 more
core   +1 more source

The Human Sodium Iodide Symporter as a Reporter Gene for Studying Middle East Respiratory Syndrome Coronavirus Pathogenesis

mSphere, 2018
Single photon emission computed tomography (SPECT) is frequently used in oncology and cardiology to evaluate disease progression and/or treatment efficacy.
Svetlana Chefer, Jurgen Seidel, Adam S. Cockrell, Boyd Yount, Jeffrey Solomon, Katie R. Hagen, David X. Liu, Louis M. Huzella, Mia R. Kumar, Elena Postnikova, J. Kyle Bohannon, Matthew G. Lackemeyer, Kurt Cooper, Ariel Endlich-Frazier, Heema Sharma, David Thomasson, Christopher Bartos, Philip J. Sayre, Amy Sims, Julie Dyall, Michael R. Holbrook, Peter B. Jahrling, Ralph S. Baric, Reed F. Johnson   +23 more
doaj   +1 more source

Specific Bacterial Pathogen Phytosensing Is Enabled by a Synthetic Promoter-Transcription Factor System in Potato

Frontiers in Plant Science, 2022
Phytosensors are genetically engineered plant-based sensors that feature synthetic promoters fused to reporter genes to sense and report the presence of specific biotic and abiotic stressors on plants.
Ramona Persad-Russell, Ramona Persad-Russell, Mitra Mazarei, Mitra Mazarei, Tayler Marie Schimel, Tayler Marie Schimel, Lana Howe, Lana Howe, Manuel J. Schmid, Manuel J. Schmid, Tayebeh Kakeshpour, Tayebeh Kakeshpour, Caitlin N. Barnes, Caitlin N. Barnes, Holly Brabazon, Holly Brabazon, Erin M. Seaberry, Erin M. Seaberry, D. Nikki Reuter, D. Nikki Reuter, Scott C. Lenaghan, Scott C. Lenaghan, C. Neal Stewart, C. Neal Stewart   +23 more
doaj   +1 more source

Optimisations and challenges involved in the creation of various bioluminescent and fluorescent influenza a virus strains for in vitro and in vivo applications [PDF]

, 2015
Bioluminescent and fluorescent influenza A viruses offer new opportunities to study influenza virus replication, tropism and pathogenesis. To date, several influenza A reporter viruses have been described.
Bestebroer, T.M. (Theo), Bárcena, M. (Montserrat), Fouchier, R.A.M. (Ron), Graaf, M.T. (Marieke) de, Gultyaev, A.P. (Alexander), Herfst, S. (Sander), Koster, A.J. (Abraham J.), Kremers, G.J. (Gert-Jan), Rimmelzwaan, G.F. (Guus), Scott, D.P. (Dana P.), Short, K.R. (Kirsty), Sorell, E.M. (Erin M.), Spronken, M.I. (Monique), Vaes, V.P. (Vincent P.), Van Der Hoeven, B. (Barbara)   +14 more
core   +1 more source

A Sensitive Sensor Cell Line for the Detection of Oxidative Stress Responses in Cultured Human Keratinocytes

Sensors, 2014
In the progress of allergic and irritant contact dermatitis, chemicals that cause the generation of reactive oxygen species trigger a heat shock response in keratinocytes.
Ute Hofmann, Melanie Priem, Christine Bartzsch, Thomas Winckler, Karl-Heinz Feller   +4 more
doaj   +1 more source