Results 11 to 20 of about 505,216 (312)

The cholesterol esterification inhibitor avasimibe suppresses tumour proliferation and metastasis via the E2F-1 signalling pathway in prostate cancer

open access: yesCancer Cell International, 2021
Background New effective drugs for prostate cancer (PCa) treatment are urgently needed. Avasimibe was recently identified as a promising drug for anticancer therapies.
Kangping Xiong   +9 more
doaj   +1 more source

Immune‐related signature predicts the prognosis and immunotherapy benefit in bladder cancer

open access: yesCancer Medicine, 2020
Background There is no good prognostic model that could predict the prognosis of bladder cancer (BCa) and the benefit of immunotherapy. Methods Through the least absolute shrinkage and selection operator (LASSO) algorithm, we constructed a 13‐mRNA immune
Yejinpeng Wang   +8 more
doaj   +1 more source

Comparing Repository Types: Challenges and Barriers for Subject-Based Repositories, Research Repositories, National Repository Systems and Institutional Repositories in Serving Scholarly Communication [PDF]

open access: yesSSRN Electronic Journal, 2009
After two decades of repository development, some conclusions may be drawn as to which type of repository and what kind of service best supports digital scholarly communication. In this regard, four types of publication repository may be distinguished, namely the subject-based repository, research repository, national repository system, and ...
Armbruster, Chris, Romary, Laurent
openaire   +4 more sources

Repositories

open access: yes, 2020
Slidedeck on Data ...
Sefryn Penrose   +2 more
  +4 more sources

Integration of Open Educational Resources Using Semantic Platform

open access: yesIEEE Access, 2021
Universities around the world have been taking advantage of open educational resources (OERs) for publishing educational material. The teachers and students can access, the published material for teaching, learning and research through institutional ...
Cristal Galindo Duran   +1 more
doaj   +1 more source

Analysis of the Interaction Network of Hub miRNAs-Hub Genes, Being Involved in Idiopathic Pulmonary Fibers and Its Emerging Role in Non-small Cell Lung Cancer

open access: yesFrontiers in Genetics, 2020
Idiopathic pulmonary fibrosis (IPF) is a fibrotic interstitial lung disease with lesions confined to the lungs. To identify meaningful microRNA (miRNA) and gene modules related to the IPF progression, GSE32537 (RNA-sequencing data) and GSE32538 (miRNA ...
Dong Hu Yu   +10 more
doaj   +1 more source

Dual Inhibition of BMP and WNT Signals Promotes Pancreatic Differentiation from Human Pluripotent Stem Cells

open access: yesStem Cells International, 2019
Pathological or functional loss of pancreatic beta cells is the cause of diabetes. Understanding how signaling pathways regulate pancreatic lineage and searching for combinations of signal modulators to promote pancreatic differentiation will definitely ...
Mengtian Tan   +3 more
doaj   +1 more source

Questions of quality in repositories of open educational resources: a literature review [PDF]

open access: yesResearch in Learning Technology, 2014
Open educational resources (OER) are teaching and learning materials which are freely available and openly licensed. Repositories of OER (ROER) are platforms that host and facilitate access to these resources.
Javiera Atenas, Leo Havemann
doaj   +1 more source

PENSANDO SIMPLE: MODELADO DE ARQUITECTURA EMPRESARIAL

open access: yesRevista Ingeniería, Matemáticas y Ciencias de la Información, 2023
This article seeks to generate a reflection in a simple way from the experience in the IT industry, about businessarchitecture modeling understood as a design and planning process that allows companies to organize and structuretheir ...
Gian Piero D'Amico
doaj   +1 more source

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