Results 71 to 80 of about 505,216 (312)

Beyond Institutional Repositories [PDF]

International Journal of Digital Library Systems, 2009
The current system of so-called institutional repositories, even if it was a sensible response at an earlier stage, may not answer the needs of the scholarly community, scientific communication and accompanied stakeholders in a sustainable way. However, having a robust repository infrastructure is essential to academic work.
Romary, Laurent, Armbruster, Chris
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Moving data into and out of an institutional repository: Off the map and into the territory [PDF]

, 2007
Given the recent proliferation of institutional repositories, a key strategic question is how multiple institutions - repositories, archives, universities and others—can best work together to manage and preserve research data.
Bishop, Libby
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The Fast and the FRDR: Improving Metadata for Data Discovery in Canada

Publications, 2020
The Federated Research Data Repository (FRDR), developed through a partnership between the Canadian Association of Research Libraries’ Portage initiative and the Compute Canada Federation, improves research data discovery in Canada by providing a single ...
Clara Turp, Lee Wilson, Julienne Pascoe, Alex Garnett   +3 more
doaj   +1 more source

Centralized mouse repositories [PDF]

Mammalian Genome, 2012
Because the mouse is used so widely for biomedical research and the number of mouse models being generated is increasing rapidly, centralized repositories are essential if the valuable mouse strains and models that have been developed are to be securely preserved and fully exploited.
Donahue, Leah Rae, Hrabe de Angelis, Martin, Hagn, Michael, Franklin, Craig, Lloyd, K C Kent, Magnuson, Terry, McKerlie, Colin, Nakagata, Naomi, Obata, Yuichi, Read, Stuart, Wurst, Wolfgang, Hörlein, Andreas, Davisson, Muriel T   +12 more
openaire   +3 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Alive and kicking: a progress report on Open Access, institutional repositories, and health information [PDF]

, 2007
The Open Access movement has promoted two parallel strands of information dissemination - OA publishing, and self-archiving in OA repositories. But while the original focus was peer-reviewed scientific research papers, repositories have extended their ...

core   +1 more source

Taking the C out of CVMFS [PDF]

, 2012
The Cern Virtual Machine File System is most well known as a distribution mechanism for the WLCG VOs@@ experiment software; as a result, almost all the existing expertise is in installing clients mount the central Cern repositories. We report the results
Doherty, Thomas, Skipsey, Samuel, Turner, A G D   +2 more
core   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source