Results 221 to 230 of about 308,170 (360)
Establishment and Maintenance of Repressed Chromatin States on Dosage-Compensated Sex Chromosomes. [PDF]
Eduful J, LeSarge L, Csankovszki G.
europepmc +1 more source
Checkpoint Blockade Rescues the Repressive Effect of Histone Deacetylases Inhibitors on γδ T Cell Function [PDF]
Sajad A. Bhat +2 more
openalex +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Epigenetic Biomarkers for Predicting Nucleoside Analog Drug Response and Resistance in Cancer. [PDF]
Kaszycki J, Lin JC, Kim M, Jung H.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
BCOR Mutations Deregulate Cell Cycle and Hypoxic Adaptation Pathways in Retinoblastoma. [PDF]
Zhang MG +8 more
europepmc +1 more source
Evolutionarily conserved repressive activity of WOX proteins mediates leaf blade outgrowth and floral organ development in plants [PDF]
Hao Lin +5 more
openalex +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source

