Results 51 to 60 of about 136,304 (310)
Efforts of the Communist Party of Lithuania to liquidate the partisan movement
Genocidas ir Rezistencija, 1998 The Central Committee of the All–Union Communist Party of the Soviet Union, which repeatedly discussed the activities of the LSSR’s party organisation in the post–war years, demanded the “immediate fulfilment of its most pressing task – the liquidation ...
Liudas Truska
doaj +1 more source
Computational modeling to elucidate molecular mechanisms of epigenetic memory
, 2015 How do mammalian cells that share the same genome exist in notably distinct phenotypes, exhibiting differences in morphology, gene expression patterns, and epigenetic chromatin statuses?
Alsing +68 more
core +1 more source
Drosophila miR2 Primarily Targets the m7GpppN Cap Structure for Translational Repression [PDF]
Molecular Cell, 2009 Understanding the molecular mechanism(s) of how miRNAs repress mRNA translation is a fundamental challenge in RNA biology. Here we use a validated cell-free system from Drosophila embryos to investigate how miR2 inhibits translation initiation. By screening a library of chemical m7GpppN cap structure analogs, we identified defined modifications of the ...
Zdanowicz, Agnieszka +7 more
openaire +3 more sources
Structure and dynamics of the quaternary hunchback mRNA translation repression complex
Nucleic Acids Research, 2021 Abstract A key regulatory process during Drosophila development is the localized suppression of the hunchback mRNA translation at the posterior, which gives rise to a hunchback gradient governing the formation of the anterior-posterior body axis.
Jakub Macošek +16 more
openaire +5 more sources
Pecular files od USSR NKVD-MVD as sourse of news time history.
Genocidas ir Rezistencija, 1998 This article presents the documents contained in Stalin’s ‘Special folder’ files, which reflect the post–war situation in Lithuania. The documents relating to Lithuania can be broken down into the following categories: the activities of the repressive ...
Mindaugas Pocius
doaj +1 more source
Antagonistic and cooperative AGO2-PUM interactions in regulating mRNAs. [PDF]
, 2018 Approximately 1500 RNA-binding proteins (RBPs) profoundly impact mammalian cellular function by controlling distinct sets of transcripts, often using sequence-specific binding to 3' untranslated regions (UTRs) to regulate mRNA stability and translation ...
Estep, Jason A +4 more
core +3 more sources
p53 Targets Chromatin Structure Alteration to Repress α-Fetoprotein Gene Expression [PDF]
Journal of Biological Chemistry, 2001 Many of the functions ascribed to p53 tumor suppressor protein are mediated through transcription regulation. We have shown that p53 represses hepatic-specific alpha-fetoprotein (AFP) gene expression by direct interaction with a composite HNF-3/p53 DNA binding element.
S K, Ogden +5 more
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Soviet Occupation Actions to Demoralise and Break up Lithuanian Resistance in the Summer of 1945
Genocidas ir Rezistencija, 1998 In the summer of 1945, the Russian occupiers were not planning to change their tactics in suppressing military resistance in Lithuania. The most important means of suppression was, as before, the military force of the NKVD and NKGB.
Kęstutis Kasparas
doaj +1 more source
The Democratic Biopolitics of PrEP [PDF]
, 2019 PrEP (Pre-Exposure Prophylaxis) is a relatively new drug-based HIV prevention technique and an important means to lower the HIV risk of gay men who are especially vulnerable to HIV.
Adam D Galinsky +84 more
core +5 more sources