Results 251 to 260 of about 496,166 (395)

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

Genome sequence of bacteriophage AmiCi24 isolated using <i>Arthrobacter globiformis</i>. [PDF]

MicroPubl Biol
Baldwin P, Bennett M, Buonamici E, Isik H, Isik N, Li V, Mazakas M, Modi A, Muppoor N, Oliver K, Patel V, Tabak K, Weber L, Yu J, Farber M, Bogush M.   +15 more
europepmc   +1 more source

A Kruüppel-Associated Box-Zinc Finger Protein, NT2, Represses Cell-Type-Specific Promoter Activity of the α2(XI) Collagen Gene

, 2002
Kazuhiro Tanaka, Noriyuki Tsumaki, Christine A. Kozak, Yoshihiro Matsumoto, Fumihiko Nakatani, Yukihide Iwamoto, Yoshihiko Yamada   +6 more
openalex   +1 more source

Domestication of Tartary Buckwheat Shaped a Regulatory Module for Seedling Salt Tolerance by Targeting the Magnesium Transporter Gene FtMGT2

Advanced Science, EarlyView.
Domestication of Tartary buckwheat is selected for a salt tolerance mechanism involving the magnesium transporter FtMGT2. Its expression is controlled by the FtAGL16‐FtMYB15L module, which is stabilized under salt stress through a competitive interaction that blocks its degradation by the E3 ligase FtBRG1, ultimately boosting Na⁺ efflux and plant ...
Xiang Lu, Yuqi He, Wenfeng Weng, Zebin Liu, Yuanfen Gao, Yaliang Shi, Wei Li, Dili Lai, Mengyu Zhao, Rintu Jha, Hui Zhao, Guangsheng Li, Chaonan Guan, Shuai Shao, Jingjun Ruan, Sun Hee Woo, Yinan Ouyang, Muriel Quinet, Milen I. Georgiev, Alisdair R. Fernie, Congcong Hou, Kaixuan Zhang, Xu Liu, Meiliang Zhou   +23 more
wiley   +1 more source

Novel <i>Bacillus</i>-Infecting Phage <i>Bquatquinnuvirus eskimopiis</i> (Strains B450T and B450C), Founder of a New Genus, and the Properties of Its Endolysin. [PDF]

Int J Mol Sci
Kazantseva OA, Koposova ON, Shorokhova IA, Kulyabin VA, Shadrin AM.   +4 more
europepmc   +1 more source

Rice JASMONIC ACID OXIDASES control resting jasmonate metabolism to promote growth and repress basal immune responses [PDF]

Simon Y. A. Ndecky, Ludivine Malherbe, Claire Villette, Véronique Chalvon, Isabelle Meusnier, Dennisse Beltran-Valencia, Nicolas Baumberger, Michael Riemann, Thomas Kroj, Antony Champion, Thierry Heitz   +10 more
openalex   +1 more source

ROS1, a Repressor of Transcriptional Gene Silencing in Arabidopsis, Encodes a DNA Glycosylase/Lyase

Cell, 2002
Z. Gong, T. Morales-Ruiz, R. R. Ariza, T. Roldán-Arjona, Lisa David, Jian‐Kang Zhu   +5 more
semanticscholar   +1 more source

Notch2 Directs aTreg Cell Fate toward Immunoregulation or Inflammatory Pyroptosis

Advanced Science, EarlyView.
Schematic illustration showing that the Notch2 intracellular domain (NICD2) facilitates pyroptosis resistance in activated Tregs through the RREB1/Foxo1 signaling pathway. In addition, Notch2‐mediated pyroptosis resistance in activated Tregs promotes immunoregulatory capacity, thereby attenuating Th2‐driven inflammatory responses in allergic rhinitis ...
Yue‐Long Qiao, Shan Xu, You Zou, Rui Yang, Han Zheng, Jia‐Yu Liu, Hui‐Ming Fan, Yuan‐Yuan Zhang, Yong‐Gang Kong, Wo‐Er Jiao, Shi‐Ming Chen   +10 more
wiley   +1 more source

Tracking Copper sensing operon Repressor (CsoR) oligomerization in solution using Electron Paramagnetic Resonance spectroscopy. [PDF]

Protein Sci
Igbaria-Jaber Y, Mandato A, Hofmann L, Shenberger Y, Gevorkyan-Airapetov L, Sapir L, Saxena S, Ruthstein S.   +7 more
europepmc   +1 more source

Adenovirus E1A represses the cyclic AMP-induced transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) in hepatoma cells.

, 1992
Dhananjaya V. Kalvakolanu, Jing Liu, R. W. Hanson, Marian L. Harter, Ganes C. Sen   +4 more
openalex   +1 more source