Results 231 to 240 of about 483,350 (345)

C-repeat binding factor proteins integrate cold signaling into the SVP-mediated flowering pathway in Arabidopsis. [PDF]

Plant Physiol
Wang Z, Guo Z, Gao Y, Hong Y, Zhu JK, Wang Z.   +5 more
europepmc   +1 more source

Human Alu RNA is a modular transacting repressor of mRNA transcription during heat shock.

Molecules and Cells, 2008
Peter D. Mariner, Ryan D. Walters, Celso A. Espinoza, L. F. Drullinger, Stacey D. Wagner, Jennifer F. Kugel, J. Goodrich   +6 more
semanticscholar   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

SWEET tea: transcriptional regulation of sugar transporters in stress and development. [PDF]

J Exp Bot
Zhang X, Liesche J.
europepmc   +1 more source

Transcription Repressor HANABA TARANU Controls Flower Development by Integrating the Actions of Multiple Hormones, Floral Organ Specification Genes, and GATA3 Family Genes in Arabidopsis[W]

The Plant Cell, 2013
Xiaolan Zhang, Yun Zhou, Lian Ding, Zhigang Wu, Renyi Liu, E. Meyerowitz   +5 more
semanticscholar   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

More than a defense: salicylic acid's secret role in fruit color. [PDF]

Plant Cell
Prakash V.
europepmc   +1 more source

Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor.

Cell, 1997
P. Aza‐Blanc, F. Ramirez-Weber, M. Laget, Carol Schwartz, T. Kornberg   +4 more
semanticscholar   +1 more source

N4‐acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

Advanced Science, EarlyView.
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley   +1 more source