Results 251 to 260 of about 264,694 (307)

Lac Repressor

Angewandte Chemie International Edition in English, 1971
AbstractRepressors are proteins that interact with inducers and operators to regulate the synthesis of enzymes in the cell. Lac repressor ensures that sufficient β‐galactosidase is available to the bacterium Escherichia coli, depending upon the amount of lactose present in the culture medium. It has proved possible to isolate lac repressor from E.coli.
Benno Müller-Hill
exaly   +3 more sources

Co‐repressors 2000

The FASEB Journal, 2000
ABSTRACT In the last 5 years, many co‐repressors have been identified in eukaryotes that function in a wide range of species, from yeast to Drosophila and humans. Co‐repressors are coregulators that are recruited by DNA‐bound transcriptional silencers and play essential ...
Burke, Les J., Baniahmad, Aria
openaire   +5 more sources

Repressors of photomorphogenesis

2002
The internal programs of plant development are informed in a profound way by environmental light conditions. This review summarizes the contribution of repressor proteins to the light-signaling machinery during seedling development, and discusses the integration of repressors with other, positively acting, light-signaling pathways and auxin and ...
Tae-Houn, Kim, Byung-Hoon, Kim, Albrecht G, von Arnim   +2 more
openaire   +2 more sources

A mechanism for repressor action

Journal of Molecular Biology, 1969
Abstract Deletion mutants have been isolated in which the three structural genes of the lac operon, z , y and a , and the lac operator are fused to the trp operon. In most of these strains, the rate of lac operon expression is greatly increased by the derepression of the trp operon.
W S, Reznikoff, J H, Miller, J G, Scaife, J R, Beckwith   +3 more
openaire   +2 more sources

Toti“potent” repressors

BioEssays, 2006
AbstractA fascinating property of germ cells is their ability to maintain totipotency throughout development. At fertilization, this totipotency is unleashed and the egg generates all the cell types needed to make a brand new organism. Occasionally, germ cells differentiate precociously in the embryo or in the gonads and form teratomas, tumors ...
Christopher M, Gallo, Geraldine, Seydoux
openaire   +2 more sources

Studies of a thermolabile repressor

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1965
Abstract From physiological and genetic evidence, it is concluded that the repressor for β-galactosidase (EC 3.2.1.23) synthesis in a mutant bacterium, E-103, is thermolabile. The apparent inactivation of repressor is first order and irreversible; however, paradoxically, only a characteristic fraction can be inactivated at a given temperature ...
T, Horiuchi, A, Novick
openaire   +2 more sources

Translational repressors in Drosophila

Trends in Genetics, 2002
Translational regulation is an important aspect of gene regulation, particularly during early development of the fruit fly embryo when transcriptional mechanisms are untenable. Study of pattern formation and dosage compensation has identified several repressors that bind discrete sites in the untranslated portions of target mRNAs.
Kellie A, Dean, Aneel K, Aggarwal, Robin P, Wharton   +2 more
openaire   +2 more sources

Crystallization of the Arc repressor

Journal of Molecular Biology, 1985
Arc, a repressor from Salmonella phage P22 has been crystallized from ammonium phosphate at pH 8.0. The crystals form in space group P212121 with a = 90.26 A, b = 52.88 A and c = 47.58 A. The crystals diffract to 2.2 A resolution.
S R, Jordan, C O, Pabo, A K, Vershon, R T, Sauer   +3 more
openaire   +2 more sources

Repressors of healthy ageing

Nature Reviews Genetics, 2020
RNA interference screening in Caenorhabditis elegans has identified two repressive epigenetic regulators of age-related behavioural performance that are conserved in mammals.
openaire   +2 more sources