Results 261 to 270 of about 264,694 (307)

Construction of A Dimeric Repressor: Dissection of Subunit Interfaces in Lac Repressor

Biochemistry, 1994
Formation of the lactose repressor tetramer is postulated to involve two subunit interfaces, one primarily contributing to monomer-monomer assembly to dimer and the second to dimer-dimer association to tetramer. The latter interface requires a heptad repeat of three leucines at the C-terminus of lac repressor that is presumed to form an abbreviated ...
J, Chen, R, Surendran, J C, Lee, K S, Matthews   +3 more
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Interaction of effecting ligands with lac repressor and repressor-operator complex

Biochemistry, 1975
The equilibrium association constants for the binding of a wide variety of effecting ligands of the lac repressor were measured by equilibrium dialysis. Also, detailed investigations of the apparent rate of dissociation of repressor-operator comples as a function of ligand concentration were carried out for several inducers and anti-inducers.
M D, Barkley, A D, Riggs, A, Jobe, S, Burgeois   +3 more
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The Whole Lactose Repressor

Science, 1996
The lactose repressor turns the bacterial genes for lactose metabolism on and off. This system has served as a blueprint for the study of both eukaryotic and prokaryotic gene regulation for decades. In this issue of Science , the crystal structure of the whole lactose repressor in a complex with DNA and its inducer ...
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Beyond the Balance of Activator and Repressor

Science Signaling, 2011
Transcription factor binding site affinity has a counterintuitive effect on the regulation of gene expression in response to Hedgehog.
Jolma Arttu, Taipale Jussi, Jolma Arttu, Taipale Jussi   +3 more
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lac repressor-operator interaction. Analysis of the X86 repressor mutant

Journal of Molecular Biology, 1976
Abstract In vitro measurements show that the X86 repressor, which has an increased affinity for the lac operator as compared to wild-type repressor, also has an increased affinity for non-operator sites on Escherichia coli DNA. The rate constant of association of repressor and operator is decreased by E.
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Genetic Repressors

Scientific American, 1970
M, Ptashne, W, Gilbert
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Repressors

1976
S, Bourgeois, M, Pfahl
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Regulation of the lactose repressor

International Journal of Biochemistry, 1988
A E, Chakerian, K S, Matthews
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Growth-instability of repressor

Journal of Molecular Biology, 1968
S D, Barbour, C, Gross, A, Novick
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MYB Repressors as Regulators of Phenylpropanoid Metabolism in Plants

Trends in Plant Science, 2019
Dawei Ma, C Peter Constabel
exaly