Results 311 to 320 of about 334,121 (353)

Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles

Advanced Science, EarlyView.
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang, Shiying Zhang, Irene Shuping Zhao, Xueqi Gan, Yang Zhang   +4 more
wiley   +1 more source

Engineered transcription activator-like effector dimer proteins confer DNA loop-dependent gene repression comparable to Lac repressor. [PDF]

Nucleic Acids Res
Becker NA, Peters JP, Lewis E, Daby CL, Clark K, Maher LJ.   +5 more
europepmc   +1 more source

Aryl hydrocarbon receptor repressor ( AHRR ) methylation predicts risk of vascular disease: A cohort study of the general population. [PDF]

Int J Surg
Skov-Jeppesen SM, Kobylecki CJ, Jacobsen KK, Bojesen SE.   +3 more
europepmc   +1 more source

The Bitter Taste of Brazil's Temporary Import Ban on Robusta Coffee

Agribusiness, EarlyView.
ABSTRACT Brazil, a leading Robusta coffee producer and exporter, faced a significant drought in 2016–2017, which drastically reduced production and depleted stocks. Consequently, Brazil temporarily permitted the import of one million 60‐kg bags of Robusta coffee in the spring 2017. An import ban was imposed shortly afterward due to lobbying by domestic
Hanifi Otgun, John Beghin, Fernando Maximiliano   +2 more
wiley   +1 more source

Tuning and functionalization of logic gates for time resolved programming of bacterial populations. [PDF]

Nucleic Acids Res
Bäcker LE, Broux K, Weckx L, Khanal S, Aertsen A.   +4 more
europepmc   +1 more source

Phage parasites targeting phage homologous recombinases provide antiviral immunity. [PDF]

Nat Commun
Debiasi-Anders G, Qiao C, Salim A, Li N, Mir-Sanchis I.   +4 more
europepmc   +1 more source

Absence of CDK12 in oocyte leads to female infertility. [PDF]

Cell Death Dis
Jansova D, Sedmikova V, Berro FJ, Aleshkina D, Dvoran M, Kubelka M, Rezacova J, Rutarova J, Kohoutek J, Susor A.   +9 more
europepmc   +1 more source

Mutations leading to ceftolozane/tazobactam and imipenem/cilastatin/relebactam resistance during <i>in vivo</i> exposure to ceftazidime/avibactam in <i>Pseudomonas aeruginosa</i>. [PDF]

Microbiol Spectr
Rapsinski GJ, Rokes AB, Van Tyne D, Cooper VS.   +3 more
europepmc   +1 more source

Design and Characterization of a Transcriptional Repression Toolkit for Plants. [PDF]

ACS Synth Biol
Markel K, Sabety J, Wijesinghe S, Shih PM.   +3 more
europepmc   +1 more source

Insect wings arose with a genetic circuit that extends the useful range of a BMP morphogen

Huang A, Cocconi L, Nicholls-Mindlin B, Alexandre C, Salbreux G, Vincent J.   +5 more
europepmc   +1 more source