Results 311 to 320 of about 382,695 (354)
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Studies of a thermolabile repressor

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1965
Abstract From physiological and genetic evidence, it is concluded that the repressor for β-galactosidase (EC 3.2.1.23) synthesis in a mutant bacterium, E-103, is thermolabile. The apparent inactivation of repressor is first order and irreversible; however, paradoxically, only a characteristic fraction can be inactivated at a given temperature ...
Tadao Horiuchi, Aaron Novick
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Translational repressors in Drosophila

Trends in Genetics, 2002
Translational regulation is an important aspect of gene regulation, particularly during early development of the fruit fly embryo when transcriptional mechanisms are untenable. Study of pattern formation and dosage compensation has identified several repressors that bind discrete sites in the untranslated portions of target mRNAs.
Aneel K. Aggarwal   +2 more
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Repression and Repressors

European Psychologist, 1997
The present article reviews and evaluates the history of theory and research on the concept of repression and, its personality characteristic, the repressive coping style. The four-factor theory ( Eyseneck, 1997 ), a comprehensive cognitive theory of repressors, attempts to provide evidence for the avoidant or defensive cognitive processors allegedly ...
Michael W. Eysenck, Nazanin Derakshan
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The Repressor Within

Science Signaling, 2011
An internal promoter drives expression of a truncated transcription factor that acts as a dominant-negative repressor of Wnt-responsive genes.
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Crystallization of the Arc repressor

Journal of Molecular Biology, 1985
Arc, a repressor from Salmonella phage P22 has been crystallized from ammonium phosphate at pH 8.0. The crystals form in space group P212121 with a = 90.26 A, b = 52.88 A and c = 47.58 A. The crystals diffract to 2.2 A resolution.
Steven R. Jordan   +3 more
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Interaction of effecting ligands with lac repressor and repressor-operator complex

Biochemistry, 1975
The equilibrium association constants for the binding of a wide variety of effecting ligands of the lac repressor were measured by equilibrium dialysis. Also, detailed investigations of the apparent rate of dissociation of repressor-operator comples as a function of ligand concentration were carried out for several inducers and anti-inducers.
Arthur D. Riggs   +4 more
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Construction of A Dimeric Repressor: Dissection of Subunit Interfaces in Lac Repressor

Biochemistry, 1994
Formation of the lactose repressor tetramer is postulated to involve two subunit interfaces, one primarily contributing to monomer-monomer assembly to dimer and the second to dimer-dimer association to tetramer. The latter interface requires a heptad repeat of three leucines at the C-terminus of lac repressor that is presumed to form an abbreviated ...
James C. Lee   +3 more
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Beyond the Balance of Activator and Repressor

Science Signaling, 2011
Transcription factor binding site affinity has a counterintuitive effect on the regulation of gene expression in response to Hedgehog.
Arttu Jolma   +4 more
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Repressors of healthy ageing

Nature Reviews Genetics, 2020
RNA interference screening in Caenorhabditis elegans has identified two repressive epigenetic regulators of age-related behavioural performance that are conserved in mammals.
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The Whole Lactose Repressor

Science, 1996
The lactose repressor turns the bacterial genes for lactose metabolism on and off. This system has served as a blueprint for the study of both eukaryotic and prokaryotic gene regulation for decades. In this issue of Science , the crystal structure of the whole lactose repressor in a complex with DNA and its inducer ...
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