Results 31 to 40 of about 332,235 (353)
Negative feedback control of jasmonate signaling by an alternative splice variant of JAZ10 [PDF]
The plant hormone jasmonate (JA) activates gene expression by promoting ubiquitin-dependent degradation of JAZ transcriptional repressor proteins. A key feature of all JAZ proteins is the highly conserved Jas motif, which mediates both JAZ degradation ...
Campos, Marcelo L.+7 more
core +1 more source
Crystal and cocrystal structures of the LacI and PurR repressors reveal a novel use of hinge alpha helices which bind in the minor groove of the operator and mediate transmission of the allosteric signals that modulate DNA-binding activity.
openaire +3 more sources
The phospholipid acyl chains of Enterococcus faecalis can be derived either by de novo synthesis or by incorporation of exogenous fatty acids through the fatty acid kinase complex (Fak)-phosphate acyltransferase (PlsX) pathway.
Qi Zou+4 more
doaj +1 more source
A factor implicated in autism spectrum disorders can both suppress and activate the expression of genes involved in neurodevelopment.
Michael E. Greenberg+2 more
openaire +2 more sources
Streptococcus suis is an important pathogen in both pigs and humans. Although the diseases associated with S. suis can typically be treated with antibiotics, such use has resulted in a sustained increase in drug resistance. Bacteria can sense and respond
Xia Yang+7 more
doaj +1 more source
Crystallization and preliminary crystallographic analysis of dUTPase from the helper phage Φ11 of Staphylococcus aureus [PDF]
Staphylococcus aureus superantigen-carrying pathogenicity islands (SaPIs) have a determinant role in spreading virulence genes among bacterial populations that constitute a major health hazard.
Bendes, Ábris+5 more
core +1 more source
Allelic expression mapping across cellular lineages to establish impact of non‐coding SNPs
Most complex disease‐associated genetic variants are located in non‐coding regions and are therefore thought to be regulatory in nature. Association mapping of differential allelic expression (AE) is a powerful method to identify SNPs with direct cis ...
Veronique Adoue+16 more
doaj +1 more source
The GbsR Family of Transcriptional Regulators: Functional Characterization of the OpuAR Repressor
Accumulation of compatible solutes is a common stress response of microorganisms challenged by high osmolarity; it can be achieved either through synthesis or import.
Stefanie Ronzheimer+4 more
doaj +1 more source
Conversion of graded to binary response in an activator-repressor system [PDF]
Appropriate regulation of gene expression is essential to ensure that protein synthesis occurs in a selective manner. The control of transcription is the most dominant type of regulation mediated by a complex of molecules such as transcription factors. In general, regulatory molecules are of two types: activator and repressor.
arxiv +1 more source
Because of the long and unpredictable flowering period in bamboo, the molecular mechanism of bamboo flowering is unclear. Recent study showed that Arabidopsis PIN1-type parvulin 1 (Pin1At) is an important floral activator and regulates floral transition ...
Zhigang Zheng+5 more
doaj +1 more source