Results 31 to 40 of about 360,363 (303)

The trans-activation domain of the sporulation response regulator Spo0A revealed by X-ray crystallography [PDF]

, 2000
Sporulation in Bacillus involves the induction of scores of genes in a temporally and spatially co-ordinated programme of cell development. Its initiation is under the control of an expanded two-component signal transduction system termed a phosphorelay.
Baldus J.M., Brown D.P., Buckner C.M., Buckner C.M., Busby S., Chung J.D., Cowtan K., Ferrari F.A., Fogh R.H., Green B.D., Grimsley J.K., Hatt J.K., Igarashi K., Ireton K., Kenney T.J., Kondo H., Kuldell N., Makino K., Martinez-Hackert E., Muchova K., Murshudov G.N., Olmedo G., Perego M., Satola S.W., Schyns G., Spiegelman G.B., Spiegelman G.B., Strauch M.A., Strauch M.A., Terwilliger T.C., Weir J., Wu H.-M., York K.   +32 more
core   +1 more source

Role of the Two-Component System CiaRH in the Regulation of Efflux Pump SatAB and Its Correlation with Fluoroquinolone Susceptibility

Microbiology Spectrum, 2022
Streptococcus suis is an important pathogen in both pigs and humans. Although the diseases associated with S. suis can typically be treated with antibiotics, such use has resulted in a sustained increase in drug resistance. Bacteria can sense and respond
Xia Yang, Wei Peng, Ningning Wang, Beibei Dou, Fengming Yang, Huanchun Chen, Fangyan Yuan, Weicheng Bei   +7 more
doaj   +1 more source

The Enterococcus faecalis FabT Transcription Factor Regulates Fatty Acid Biosynthesis in Response to Exogeneous Fatty Acids

Frontiers in Microbiology, 2022
The phospholipid acyl chains of Enterococcus faecalis can be derived either by de novo synthesis or by incorporation of exogenous fatty acids through the fatty acid kinase complex (Fak)-phosphate acyltransferase (PlsX) pathway.
Qi Zou, Huijuan Dong, Lei Zhu, John E. Cronan, John E. Cronan   +4 more
doaj   +1 more source

Finding the center reliably: robust patterns of developmental gene expression

, 2005
We investigate a mechanism for the robust identification of the center of a developing biological system. We assume the existence of two morphogen gradients, an activator emanating from the anterior, and a co-repressor from the posterior.
A. Eldar, A. M. Turing, A. V. Spirov, B. Houchmandzadeh, C. Zhao, H. Meinhardt, L. Wolpert, Martin Howard, Pieter Rein ten Wolde, X. Ma   +9 more
core   +1 more source

Functional Mechanism of the Efflux Pumps Transcription Regulators From Pseudomonas aeruginosa Based on 3D Structures

Frontiers in Molecular Biosciences, 2018
Bacterial antibiotic resistance is a worldwide health problem that deserves important research attention in order to develop new therapeutic strategies.
Karim Housseini B Issa, Gilles Phan, Isabelle Broutin   +2 more
doaj   +1 more source

RETRACTED: LacI-Family Transcriptional Regulator DagR Acts as a Repressor of the Agarolytic Pathway Genes in Streptomyces coelicolor A3(2)

Frontiers in Microbiology, 2021
Actinobacteria utilize various polysaccharides in the soil as carbon source by degrading them via extracellular hydrolytic enzymes. Agarose, a marine algal polysaccharide composed of D-galactose and 3,6-anhydro-L-galactose (AHG), is one of the carbon ...
Maral Tsevelkhoroloo, So Heon Shim, Chang-Ro Lee, Soon-Kwang Hong, Young-Soo Hong   +4 more
doaj   +1 more source

Repressors of reprogramming

World Journal of Stem Cells, 2015
Induced pluripotent stem cells (iPSCs) have been the focal point of ever increasing interest and scrutiny as they hold the promise of personalized regenerative medicine. However, creation of iPSCs is an inefficient process that requires forced expression of potentially oncogenic proteins.
Melissa, Popowski, Haley, Tucker
openaire   +2 more sources

Gene regulatory network subcircuit controlling a dynamic spatial pattern of signaling in the sea urchin embryo [PDF]

, 2008
We dissect the transcriptional regulatory relationships coordinating the dynamic expression patterns of two signaling genes, wnt8 and delta, which are central to specification of the sea urchin embryo endomesoderm.
Alifragis, Davidson, Dawson, E. H. Davidson, Fisher, Giagtzoglou, Gyory, Howard-Ashby, Howard-Ashby, J. Smith, Kuo, Lee, Livi, Materna, McClay, Minokawa, Oellers, Oliveri, Osipovich, Peterson, Ransick, Revilla-i-Domingo, Rizzo, Robertson, Sea Urchin Genome Sequencing Consortium, Sherwood, Smith, Smith, Thirunavukkarasu, Tietze, Tu, Walton, Wikramanayake, Yu, Yuh   +34 more
core   +3 more sources

Investigation of the potential regulator proteins associated with the expression of major surface protein and dentilisin in Treponema denticola

Journal of Oral Microbiology, 2020
Objective Treponema denticola is involved in ‘chronic’ periodontitis pathogenesis. The mechanism underlying the regulation of the expression of its virulence factors, such as major surface protein (Msp) and prolyl-phenylalanine specific protease ...
Yuki Arai, Yuichiro Kikuchi, Kazuko Okamoto-Shibayama, Eitoyo Kokubu, Seikou Shintani, Kazuyuki Ishihara   +5 more
doaj   +1 more source

dUTPase based switch controls transfer of virulence genes in order to preserve integrity of the transferred mobile genetic elements [PDF]

, 2013
dUTPases ubiquitously regulate cellular dUTP levels to preserve genome integrity. Recently, several other cellular processes were reported to be controlled by dUTPases including the horizontal transfer of Staphylococcus aureus pathogenicity islands ...
Bendes, A., Besztercei, B., Leveles, I., Liliom, K., Nyíri, K., Németh-Pongrácz, V., Papp-Kádár, V., Pálinkás, H., Róna, G., Szabó, J. E., Tóth, J., Vértessy G., Beáta, Zagyva, I.   +12 more
core   +1 more source