Results 41 to 50 of about 332,235 (353)
Ten-eleven translocation proteins (TETs): tumor suppressors or tumor enhancers?
Frontiers in Bioscience-Landmark, 2021 The epigenetic memory stored in the dynamic modifications, such as base modifications of cytosine (C) in DNA, including methylation/hydroxymethylation/demethylation, causes heritable phenotypes via regulating gene expression without alteration of DNA ...
Cuili Ma +5 more
doaj +1 more source
Operator Sequence Alters Gene Expression Independently of Transcription Factor Occupancy in Bacteria [PDF]
, 2012 A canonical quantitative view of transcriptional regulation holds that the only role of operator sequence is to set the probability of transcription factor binding, with operator occupancy determining the level of gene expression.
Boedicker, James Q. +6 more
core +4 more sources
Identification of Chimeric Repressors that Confer Salt and Osmotic Stress Tolerance in Arabidopsis
Plants, 2013 We produced transgenic Arabidopsis plants that express chimeric genes for transcription factors converted to dominant repressors, using Chimeric REpressor gene-Silencing Technology (CRES-T), and evaluated the salt tolerance of each line.
Daisuke Kazama +5 more
doaj +1 more source
Effect of promoter architecture on the cell-to-cell variability in gene expression [PDF]
, 2010 According to recent experimental evidence, the architecture of a promoter, defined as the number, strength and regulatory role of the operators that control the promoter, plays a major role in determining the level of cell-to-cell variability in gene ...
A Bar-Even +104 more
core +5 more sources
Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis
Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022 One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen +3 more
wiley +1 more source
Dynamic repression by BCL6 controls the genome-wide liver response to fasting and steatosis
eLife, 2019 Transcription is tightly regulated to maintain energy homeostasis during periods of feeding or fasting, but the molecular factors that control these alternating gene programs are incompletely understood.
Meredith A Sommars +8 more
doaj +1 more source
Frontiers in Microbiology, 2021 Actinobacteria utilize various polysaccharides in the soil as carbon source by degrading them via extracellular hydrolytic enzymes. Agarose, a marine algal polysaccharide composed of D-galactose and 3,6-anhydro-L-galactose (AHG), is one of the carbon ...
Maral Tsevelkhoroloo +4 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2018 Bacterial antibiotic resistance is a worldwide health problem that deserves important research attention in order to develop new therapeutic strategies.
Karim Housseini B Issa +2 more
doaj +1 more source
Journal of Oral Microbiology, 2020 Objective Treponema denticola is involved in ‘chronic’ periodontitis pathogenesis. The mechanism underlying the regulation of the expression of its virulence factors, such as major surface protein (Msp) and prolyl-phenylalanine specific protease ...
Yuki Arai +5 more
doaj +1 more source
An epistatic mini-circuitry between the transcription factors Snail and HNF4a controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs [PDF]
, 2012 Preservation of the epithelial state involves the stable repression of EMT program while maintenance of the stem compartment requires the inhibition of differentiation processes.
AMICONE, Laura +8 more
core +1 more source